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European Journal of Medical Research
Published in: European Journal of Medical Research 1/2017

Open Access 01-12-2017 | Review

Advances in the genome-wide association study of chronic hepatitis B susceptibility in Asian population

Authors: Bing Qiu, Wei Jiang, Mojtaba Olyaee, Kenji Shimura, Akihiro Miyakawa, Huijing Hu, Yongcui Zhu, Lixin Tang

Published in: European Journal of Medical Research | Issue 1/2017

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Abstract

Chronic hepatitis B (CHB) is the most common chronic liver disease resulting from viral infection and has become a serious threat to human health. Each year, about 1.2 million people in the world die from diseases caused by chronic infection of hepatitis B virus. The genetic polymorphism is significantly associated with the susceptibility to chronic hepatitis B. Genome-wide association study was recently developed and has become an important tool to detect susceptibility genes of CHB. To date, a number of CHB-associated susceptibility loci and regions have been identified by scientists over the world. To clearly understand the role of susceptibility loci in the occurrence of CHB is important for the early diagnosis and prevention of CHB.
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Metadata
Title
Advances in the genome-wide association study of chronic hepatitis B susceptibility in Asian population
Authors
Bing Qiu
Wei Jiang
Mojtaba Olyaee
Kenji Shimura
Akihiro Miyakawa
Huijing Hu
Yongcui Zhu
Lixin Tang
Publication date
01-12-2017
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2017
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/s40001-017-0288-3

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