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Open Access 01-12-2019 | Acupuncture | Protocol

Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review

Authors: Ruan Nilton Rodrigues Melo, Stephanie Carolina Francisco, Caroline de Castro Moura, Kirsty Loudon, Namie Okino Sawada, Érika de Cássia Lopes Chaves, Tânia Couto Machado Chianca, Denismar Alves Nogueira, Si Jia Zhu, Ana Cláudia Mesquita Garcia

Published in: Systematic Reviews | Issue 1/2019

Abstract

Background

Due to the worldwide rise in cancer incidence, and therefore the rise in the need for antineoplastic chemotherapy, it is important for both healthcare professionals and patients alike that the side effects of chemotherapy, such as chemotherapy-induced nausea and vomiting (CINV), are treated and prevented. Auriculotherapy is a type of acupuncture and may be a low-cost and safe antiemetic measure to control the side effects of chemotherapy. The goal of this systematic review is to synthesize the available evidence in the literature regarding the auriculotherapy effects to treat CINV in people with cancer.

Methods

The review will only include randomized controlled trials (RCTs) that compare the clinical effects of the auriculotherapy intervention (used alone or as an add-on), with sham auriculotherapy, routine treatment with antiemetic drugs, or other non-pharmacological interventions in patients with cancer with CINV who are undergoing chemotherapy. The outcomes to be evaluated are nausea and vomiting: in acute, delayed, or anticipated stages, when induced by chemotherapy. A comprehensive search for studies will be carried out in these databases: MEDLINE via PubMed, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, ICTRP, LILACS, CUMED, IBECS, BVS MTCI Americas, Web of Science, Scopus, PEDro, CNKI, and CBMdisc up until December 31, 2018. Only articles in English, Portuguese, and Spanish will be selected. Two independent reviewers will evaluate full texts, extract data, and assess the risk of bias of eligible articles. The quality of evidence will be assessed using Grading of Recommendations, Assessment, Development and Evaluation (GRADE). A meta-analysis will be undertaken to assess the interventions and outcomes’ homogeneity, assessing statistical heterogeneity using the Cochran’s Q test and quantified using Higgins’ inconsistency index. If there is insufficient data for a meta-analysis, a narrative synthesis will be presented. This protocol has been prepared according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines.

Discussion

The results of this systematic review will summarize the strength of evidence for the use of auriculotherapy in the control of CINV of patients with cancer and will be used to identify evidence gaps.

Systematic review registration

PROSPERO CRD42018117513

Available only for authorised users

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Title: Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review
Authors: Ruan Nilton Rodrigues Melo
Stephanie Carolina Francisco
Caroline de Castro Moura
Kirsty Loudon
Namie Okino Sawada
Érika de Cássia Lopes Chaves
Tânia Couto Machado Chianca
Denismar Alves Nogueira
Si Jia Zhu
Ana Cláudia Mesquita Garcia
Publication date: 01-12-2019
Publisher: BioMed Central
Keywords: Acupuncture
Nausea
Vomiting
Cytostatic Therapy
Published in: Systematic Reviews / Issue 1/2019
Electronic ISSN: 2046-4053
DOI: https://doi.org/10.1186/s13643-019-1124-3

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review

Abstract

Background

Methods

Discussion

Systematic review registration

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Discussion

Systematic review registration

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