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Published in: Systematic Reviews 1/2019

Open Access 01-12-2019 | Psychotherapy | Protocol

Does stage of illness influence recovery-focused outcomes after psychological treatment in bipolar disorder? A systematic review protocol

Authors: Hailey Tremain, Kathryn Fletcher, Jan Scott, Carla McEnery, Michael Berk, Greg Murray

Published in: Systematic Reviews | Issue 1/2019

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Abstract

Background

There is great interest in the possibility that ‘stage of illness’ moderates treatment outcomes in bipolar disorder (BD). Much remains unknown about the construct of stage of illness, but there is evidence that effectiveness of psychosocial interventions may depend on factors that are plausible proxy measures of stage of illness (e.g., number of episodes). To date, reviews of this data have focused solely on clinical outcomes (particularly symptoms and relapse rates), but a range of recovery-focused outcomes (including functioning, cognitive functioning, and quality of life) have been measured in individuals with established BD. The aim of the proposed systematic review is to synthesise existing evidence for plausible proxy measures of stage of illness as moderators of recovery-focused and functional outcomes in psychosocial treatment studies of BD.

Methods

The proposed review will follow PRISMA guidelines; Scopus, PsychINFO, PubMed and Web of Science will be searched for empirical studies of psychosocial interventions used for established (clinical stages 2–4) BD; and findings will be summarised in a narrative synthesis of clinical stage of illness (operationalised in proxy measures identified in existing staging models) as a moderator of recovery-focused and functional outcomes of psychosocial interventions for established bipolar disorder.

Discussion

This review will contribute to the literature by expanding upon previous reviews and potentially inform the psychosocial treatment of established BD. Implications include assisting clinicians, consumers and researchers to identify and select interventions most appropriate to recovery-focused goals based on individuals’ clinical status.

Systematic review registration

PROSPERO CRD42016037868
Appendix
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Footnotes
1
We use the qualifier ‘plausible’ to remind the reader (and ourselves) that ‘staging’ remains a hypothetical construct in psychiatry. Any proxies are at best consistent with one or more of the various provisional conceptualisations of staging.
 
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Metadata
Title
Does stage of illness influence recovery-focused outcomes after psychological treatment in bipolar disorder? A systematic review protocol
Authors
Hailey Tremain
Kathryn Fletcher
Jan Scott
Carla McEnery
Michael Berk
Greg Murray
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Psychotherapy
Published in
Systematic Reviews / Issue 1/2019
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-019-1042-4

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