Skip to main content
Top
Published in: Systematic Reviews 1/2019

Open Access 01-12-2019 | Research

Effectiveness of architectural separation of septic and aseptic operating theatres for improving process quality and patient outcomes: a systematic review

Authors: Romy Scholz, Alexander Hönning, Julia Seifert, Nikolai Spranger, Dirk Stengel

Published in: Systematic Reviews | Issue 1/2019

Login to get access

Abstract

Background

Architectural division of aseptic and septic operating theatres is a distinct structural feature of surgical departments in Germany. Internationally, hygienists and microbiologists mainly recommend functional separation (i.e. aseptic procedures first) without calling for separate operating floors and rooms. However, patients with severe musculoskeletal infections (e.g. joint empyema, spondylodiscitis, deep implant-associated infections) may benefit from the permanent availability of septic operating capacities without delay caused by an ongoing aseptic surgical program. A systematic literature review on the influence of a structural separation of septic and aseptic operating theatres on process and/or outcome quality has not yet been conducted.

Methods

Systematic literature search in PubMed MEDLINE, Ovid Embase, CINAHL and the Cochrane Library, screening of referenced citations, and assessment of grey literature.

Results

A total of 572 articles were found through the systematic literature search. No head-to-head studies (neither randomised, quasi-randomised nor observational) were identified which examined the impact of structural separation of septic and aseptic operating theatres on process and/or outcome quality.

Conclusions

This review did not identify evidence in favour nor against architectural separation of septic or aseptic operating theatre. Specifically, there is no evidence of a harmful effect of architectural separation. Unless prospective studies, ideally randomised trials, will be available, it is unjustified to call for abolishing established hospital structures. Future investigations must address patient-centered endpoints, surgical site infections, process quality and hospital economy.

Systematic review registration

PROSPERO (International prospective register of systematic reviews): CRD42018086568.
Appendix
Available only for authorised users
Literature
1.
go back to reference Harnoss JC, Assadian O, Diener MK, Muller T, Baguhl R, Dettenkofer M, et al. Microbial load in septic and aseptic procedure rooms. Dtsch Arztebl Int. 2017;114(27–28):465–75.PubMedPubMedCentral Harnoss JC, Assadian O, Diener MK, Muller T, Baguhl R, Dettenkofer M, et al. Microbial load in septic and aseptic procedure rooms. Dtsch Arztebl Int. 2017;114(27–28):465–75.PubMedPubMedCentral
2.
go back to reference Bischoff P, Gastmeier P. The separation of septic and aseptic surgical areas is obsolete. Dtsch Arztebl Int. 2017;114(27–28):463–4.PubMedPubMedCentral Bischoff P, Gastmeier P. The separation of septic and aseptic surgical areas is obsolete. Dtsch Arztebl Int. 2017;114(27–28):463–4.PubMedPubMedCentral
3.
go back to reference Waeschle RM, Sliwa B, Jipp M, Putz H, Hinz J, Bauer M. Performance development of a university operating room after implementation of a central operating room management. Anaesthesist. 2016;65(8):615–28.CrossRef Waeschle RM, Sliwa B, Jipp M, Putz H, Hinz J, Bauer M. Performance development of a university operating room after implementation of a central operating room management. Anaesthesist. 2016;65(8):615–28.CrossRef
4.
go back to reference Attarian DE, Wahl JE, Wellman SS, Bolognesi MP. Developing a high-efficiency operating room for total joint arthroplasty in an academic setting. Clin Orthop Relat Res. 2013;471(6):1832–6.CrossRef Attarian DE, Wahl JE, Wellman SS, Bolognesi MP. Developing a high-efficiency operating room for total joint arthroplasty in an academic setting. Clin Orthop Relat Res. 2013;471(6):1832–6.CrossRef
5.
go back to reference Weiss G, von Baer R, Riedl S. Influence of the space layout of a surgical department on use efficiency. Chirurg. 2002;73(2):174–9.CrossRef Weiss G, von Baer R, Riedl S. Influence of the space layout of a surgical department on use efficiency. Chirurg. 2002;73(2):174–9.CrossRef
6.
go back to reference Hawkins HR, Gover RE. The design of today's operating rooms. Todays Surg Nurse. 1998;20(1):11–5. quiz 45-6PubMed Hawkins HR, Gover RE. The design of today's operating rooms. Todays Surg Nurse. 1998;20(1):11–5. quiz 45-6PubMed
7.
go back to reference Birgand G, Saliou P, Lucet JC. Influence of staff behavior on infectious risk in operating rooms: what is the evidence? Infect Control Hosp Epidemiol. 2015;36(1):93–106.CrossRef Birgand G, Saliou P, Lucet JC. Influence of staff behavior on infectious risk in operating rooms: what is the evidence? Infect Control Hosp Epidemiol. 2015;36(1):93–106.CrossRef
8.
go back to reference Attri JP, Khetarpal R, Chatrath V, Kaur J. Concerns about usage of smartphones in operating room and critical care scenario. Saudi J Anaesth. 2016;10(1):87–94.CrossRef Attri JP, Khetarpal R, Chatrath V, Kaur J. Concerns about usage of smartphones in operating room and critical care scenario. Saudi J Anaesth. 2016;10(1):87–94.CrossRef
9.
go back to reference Blood AG, Sandoval MF, Burger E, Halverson-Carpenter K. Risk and protective factors associated with surgical infections among spine patients. Surg Infect. 2017;18(3):234–49.CrossRef Blood AG, Sandoval MF, Burger E, Halverson-Carpenter K. Risk and protective factors associated with surgical infections among spine patients. Surg Infect. 2017;18(3):234–49.CrossRef
10.
go back to reference Chauveaux D. Preventing surgical-site infections: measures other than antibiotics. Orthop Traumatol Surg Res. 2015;101(1 Suppl):S77–83.CrossRef Chauveaux D. Preventing surgical-site infections: measures other than antibiotics. Orthop Traumatol Surg Res. 2015;101(1 Suppl):S77–83.CrossRef
11.
go back to reference Cristina ML, Sartini M, Schinca E, Ottria G, Spagnolo AM. Operating room environment and surgical site infections in arthroplasty procedures. J Prev Med Hyg. 2016;57(3):E142–E8.PubMedPubMedCentral Cristina ML, Sartini M, Schinca E, Ottria G, Spagnolo AM. Operating room environment and surgical site infections in arthroplasty procedures. J Prev Med Hyg. 2016;57(3):E142–E8.PubMedPubMedCentral
12.
go back to reference Dellinger EP. Teamwork and collaboration for prevention of surgical site infections. Surg Infect. 2016;17(2):198–202.CrossRef Dellinger EP. Teamwork and collaboration for prevention of surgical site infections. Surg Infect. 2016;17(2):198–202.CrossRef
13.
go back to reference Graves N, Wloch C, Wilson J, Barnett A, Sutton A, Cooper N, et al. A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review. Health Technol Assess. 2016;20(54):1–144.CrossRef Graves N, Wloch C, Wilson J, Barnett A, Sutton A, Cooper N, et al. A cost-effectiveness modelling study of strategies to reduce risk of infection following primary hip replacement based on a systematic review. Health Technol Assess. 2016;20(54):1–144.CrossRef
14.
go back to reference Kucukdurmaz F, Parvizi J. The prevention of periprosthetic joint infections. Open Orthop J. 2016;10:589–99.CrossRef Kucukdurmaz F, Parvizi J. The prevention of periprosthetic joint infections. Open Orthop J. 2016;10:589–99.CrossRef
15.
go back to reference Loftus RW. Infection control in the operating room: is it more than a clean dish? Curr Opin Anaesthesiol. 2016;29(2):192–7.CrossRef Loftus RW. Infection control in the operating room: is it more than a clean dish? Curr Opin Anaesthesiol. 2016;29(2):192–7.CrossRef
16.
go back to reference Markatos K, Kaseta M, Nikolaou VS. Perioperative skin preparation and draping in modern Total joint arthroplasty: current evidence. Surg Infect. 2015;16(3):221–5.CrossRef Markatos K, Kaseta M, Nikolaou VS. Perioperative skin preparation and draping in modern Total joint arthroplasty: current evidence. Surg Infect. 2015;16(3):221–5.CrossRef
17.
go back to reference Olmsted RN. Prevention by design: construction and renovation of health care facilities for patient safety and infection prevention. Infect Dis Clin N Am. 2016;30(3):713–28.CrossRef Olmsted RN. Prevention by design: construction and renovation of health care facilities for patient safety and infection prevention. Infect Dis Clin N Am. 2016;30(3):713–28.CrossRef
18.
go back to reference O'Neal JB, Shaw AD. Goal-directed therapy in the operating room: is there any benefit? Curr Opin Anaesthesiol. 2016;29(1):80–4.CrossRef O'Neal JB, Shaw AD. Goal-directed therapy in the operating room: is there any benefit? Curr Opin Anaesthesiol. 2016;29(1):80–4.CrossRef
19.
go back to reference Pada S, Perl TM. Operating room myths: what is the evidence for common practices. Curr Opin Infect Dis. 2015;28(4):369–74.CrossRef Pada S, Perl TM. Operating room myths: what is the evidence for common practices. Curr Opin Infect Dis. 2015;28(4):369–74.CrossRef
20.
go back to reference Prabhakar A, Wyche MQ, 3rd, Ehrhardt KP, Jr., Ma JG, Elhassan AO, Urman RD, et al. Novel improvements in perioperative sterility. J Med Pract Manage. 2015;30(6 Spec No):48–50. Prabhakar A, Wyche MQ, 3rd, Ehrhardt KP, Jr., Ma JG, Elhassan AO, Urman RD, et al. Novel improvements in perioperative sterility. J Med Pract Manage. 2015;30(6 Spec No):48–50.
21.
go back to reference Dumville JC, McFarlane E, Edwards P, Lipp A, Holmes A, Liu Z. Preoperative skin antiseptics for preventing surgical wound infections after clean surgery. Cochrane Database Syst Rev. 2015;4:CD003949. Dumville JC, McFarlane E, Edwards P, Lipp A, Holmes A, Liu Z. Preoperative skin antiseptics for preventing surgical wound infections after clean surgery. Cochrane Database Syst Rev. 2015;4:CD003949.
22.
go back to reference Reichel M, Heisig P, Kohlmann T, Kampf G. Alcohols for skin antisepsis at clinically relevant skin sites. Antimicrob Agents Chemother. 2009;53(11):4778–82.CrossRef Reichel M, Heisig P, Kohlmann T, Kampf G. Alcohols for skin antisepsis at clinically relevant skin sites. Antimicrob Agents Chemother. 2009;53(11):4778–82.CrossRef
23.
go back to reference Tanner J, Woodings D, Moncaster K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev. 2006;3:CD004122. Tanner J, Woodings D, Moncaster K. Preoperative hair removal to reduce surgical site infection. Cochrane Database Syst Rev. 2006;3:CD004122.
24.
go back to reference Harnoss JC, Partecke LI, Heidecke CD, Hubner NO, Kramer A, Assadian O. Concentration of bacteria passing through puncture holes in surgical gloves. Am J Infect Control. 2010;38(2):154–8.CrossRef Harnoss JC, Partecke LI, Heidecke CD, Hubner NO, Kramer A, Assadian O. Concentration of bacteria passing through puncture holes in surgical gloves. Am J Infect Control. 2010;38(2):154–8.CrossRef
25.
go back to reference Lehtinen SJ, Onicescu G, Kuhn KM, Cole DJ, Esnaola NF. Normothermia to prevent surgical site infections after gastrointestinal surgery: holy grail or false idol? Ann Surg. 2010;252(4):696–704.PubMedPubMedCentral Lehtinen SJ, Onicescu G, Kuhn KM, Cole DJ, Esnaola NF. Normothermia to prevent surgical site infections after gastrointestinal surgery: holy grail or false idol? Ann Surg. 2010;252(4):696–704.PubMedPubMedCentral
26.
go back to reference Anderson DJ, Podgorny K, Berrios-Torres SI, Bratzler DW, Dellinger EP, Greene L, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014;35(Suppl 2):S66–88.CrossRef Anderson DJ, Podgorny K, Berrios-Torres SI, Bratzler DW, Dellinger EP, Greene L, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014;35(Suppl 2):S66–88.CrossRef
27.
go back to reference Young SW, Zhu M, Shirley OC, Wu Q, Spangehl MJ. Do ‘Surgical helmet Systems’ or ‘Body exhaust Suits’ affect contamination and deep infection rates in arthroplasty? A systematic review. J Arthroplast. 2016;31(1):225–33.CrossRef Young SW, Zhu M, Shirley OC, Wu Q, Spangehl MJ. Do ‘Surgical helmet Systems’ or ‘Body exhaust Suits’ affect contamination and deep infection rates in arthroplasty? A systematic review. J Arthroplast. 2016;31(1):225–33.CrossRef
28.
go back to reference Tanner J, Dumville JC, Norman G, Fortnam M. Surgical hand antisepsis to reduce surgical site infection. Cochrane Database Syst Rev. 2016;1:CD004288. Tanner J, Dumville JC, Norman G, Fortnam M. Surgical hand antisepsis to reduce surgical site infection. Cochrane Database Syst Rev. 2016;1:CD004288.
29.
go back to reference Kao LS, Meeks D, Moyer VA, Lally KP. Peri-operative glycaemic control regimens for preventing surgical site infections in adults. Cochrane Database Syst Rev. 2009;3:CD006806. Kao LS, Meeks D, Moyer VA, Lally KP. Peri-operative glycaemic control regimens for preventing surgical site infections in adults. Cochrane Database Syst Rev. 2009;3:CD006806.
30.
go back to reference Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919.CrossRef Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919.CrossRef
31.
go back to reference Daschner FBM, Bönig G, Langmaack H, Brobmann G. Luft- und Bodenkeimspektren in einer septischen und aseptischen Operationseinheit. Akt Chir. 1984;19:17–20. Daschner FBM, Bönig G, Langmaack H, Brobmann G. Luft- und Bodenkeimspektren in einer septischen und aseptischen Operationseinheit. Akt Chir. 1984;19:17–20.
Metadata
Title
Effectiveness of architectural separation of septic and aseptic operating theatres for improving process quality and patient outcomes: a systematic review
Authors
Romy Scholz
Alexander Hönning
Julia Seifert
Nikolai Spranger
Dirk Stengel
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2019
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/s13643-018-0937-9

Other articles of this Issue 1/2019

Systematic Reviews 1/2019 Go to the issue