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Open Access 01-12-2018 | Protocol

Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews

Authors: Alemu S. Melka, Catherine L. Chojenta, Elizabeth G. Holliday, Deborah J. Loxton

Published in: Systematic Reviews | Issue 1/2018

Abstract

Background

In the long term, smoking cessation can decrease the risk of cancer, stroke, and heart attacks and improve overall survival. The aim of the proposed umbrella review is to summarize existing systematic reviews that assessed the effects of pharmacological interventions for smoking cessation and to evaluate the methodological quality of previously conducted systematic reviews.

Methods

Databases such as the Cochrane Library, PubMed, MEDLINE, EMBASE, CINAHIL PsychINFO Web of Science, Conference Papers Index, Scopus, and Google Scholar will be used to retrieve reviews. Systematic reviews which included only randomized control trials will be considered in this review. The primary outcome will be prolonged abstinence from smoking for a minimum of 6 months follow-up, and the secondary outcome will be point abstinence rate from smoking of less than 6 months follow-up but more than 7 days. Methodological quality of the included reviews will be assessed using the Assessment of Multiple Systematic Reviews 2 (AMSTAR 2) tool, which contains 16 domains. Two authors will screen the titles and abstracts of all reviews obtained by the search strategy, assess the full text of selected articles for inclusion, and extract data independently. The quality appraisal will be also assessed by two authors (AM, CC) independently, and Cohen’s Kappa statistic will be used to assess inter-ratter agreement. The findings of the study will be narrated qualitatively to describe the effect of different pharmacotherapy on smoking cessation.

Discussion

The World Health Organization recommends treatment of tobacco dependence as one approach in its comprehensive tobacco control policy. To date, many trials and systematic reviews have been conducted to assess the effectiveness of pharmacotherapy for smoking cessation. Therefore, the findings of the umbrella review will improve clinical decision-making and be used as a baseline for future studies.

Systematic review registration

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Ng M, Freeman MK, Fleming TD, Robinson M, Dwyer-Lindgren L, Thomson B, et al. Smoking prevalence and cigarette consumption in 187 countries, 1980–2012. Jama. 2014;311(2):183–92 https://doi.org/10.1001/jama.2013.284692.CrossRef

National Institute on Drug Abuse. Cigarettes and other tobacco products. 2017. https://www.drugabuse.gov/publications/drugfacts/cigarettes-other-tobacco-products. Accessed 9 Jan 2017.

US Department of Health and Human service. Are there effective treatments for tobacco addiction? National Institute of Health; 2016.

World Health Organization. WHO global report on trends in prevalence of tobacco smoking 2015: World Health Organization; 2015. http://apps.who.int/iris/bitstream/10665/156262/1/9789241564922_eng.pdf. Accessed 18 Jan 2017.

Office of the Surgeon General. How tobacco smoke causes disease: the biology and behavioural basis for smoking-attributable disease. Washington DC: US Department of Health and Human Services; 2010. https://www.ncbi.nlm.nih.gov/books/NBK53017/. Accessed 8 Jan 2017.

US Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General; 2006. https://www.barnesandnoble.com/w/the-health-consequences-of-involuntary-exposure-to-tobacco-smoke-department-of-human-services/1112109451. Accessed 12 Feb 2018.

Öberg M, Jaakkola MS, Woodward A, Peruga A, Prüss-Ustün A. Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries. The Lancet. 2011;377(9760):139–46 https://doi.org/10.1016/S0140-6736(10)61388-8.CrossRef

Rehm J, Rehm J, Taylor B, Rehm J, Taylor B, Room R, et al. Global burden of disease from alcohol, illicit drugs and tobacco. Drug and alcohol review. 2006;25(6):503–13 https://doi.org/10.1080/09595230600944453.CrossRef

Jiloha R. Pharmacotherapy of smoking cessation. Indian journal of psychiatry. 2014;56(1):87 https://doi.org/10.4103/0019-5545.124726.CrossRef

10.

Taylor DH Jr, Hasselblad V, Henley SJ, Thun MJ, Sloan FA. Benefits of smoking cessation for longevity. American journal of public health. 2002;92(6):990–6 https://doi.org/10.2105/AJPH.92.6.990.CrossRef

11.

U.S. Department of Health and Human Services. Reducing Tobacco Use: A Report of the Surgeon General.Atlanta, Georgia: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2000. https://www.cdc.gov/tobacco/data_statistics/sgr/2000/complete_report/pdfs/fullreport.pdf. Accessed 12 Dec 2017.

12.

Kahler CW, Spillane NS, Metrik J, Leventhal AM, Monti PM. Sensation seeking as a predictor of treatment compliance and smoking cessation treatment outcomes in heavy social drinkers. Pharmacology Biochemistry and Behavior. 2009;93(3):285–90 https://doi.org/10.1016/j.pbb.2009.01.003.CrossRef

13.

Eddy DM, Peskin B, Shcheprov A, Pawlson G, Shih S, Schaaf D. Effect of smoking cessation advice on cardiovascular disease. American Journal of Medical Quality. 2009;24(3):241–9 https://doi.org/10.1177/1062860609332509.CrossRef

14.

Tomioka H, Sekiya R, Nishio C, Ishimoto G. Impact of smoking cessation therapy on health-related quality of life. BMJ open respiratory research. 2014;1(1):e000047 https://doi.org/10.1136/bmjresp-2014-000047.CrossRef

15.

Costa e Silva Vd. Tools for advancing tobacco control in the XXIst century: policy recommendations for smoking cessation and treatment of tobacco dependence: tools for public health: World Health Organization; 2003. http://www.who.int/tobacco/resources/publications/en/intro_chapter3.pdf. Accessed 9 June 2018.

16.

Damaj MI, Slemmer J, Carroll F, Martin B. Pharmacological characterization of nicotine’s interaction with cocaine and cocaine analogs. Journal of Pharmacology and Experimental Therapeutics. 1999;289(3):1229–36. http://jpet.aspetjournals.org/content/jpet/289/3/1229.full.pdf.

17.

Covey LS, Sullivan MA, Johnston JA, Glassman AH, Robinson MD, Adams DP. Advances in non-nicotine pharmacotherapy for smoking cessation. Drugs. 2000;59(1):17–31 https://doi.org/10.2165/00003495-200059010-00003.CrossRef

18.

Roddy E. ABC of smoking cessation: bupropion and other non-nicotine pharmacotherapies. BMJ: British Medical Journal. 2004;328(7438):509 https://doi.org/10.1136/bmj.328.7438.509.CrossRef

19.

Mihalak KB, Carroll FI, Luetje CW. Varenicline is a partial agonist at α4β2 and a full agonist at α7 neuronal nicotinic receptors. Molecular pharmacology. 2006;70(3):801–5 https://doi.org/10.1124/mol.106.025130.CrossRef

20.

Ayo-Yusuf OA, Szymanski B. Factors associated with smoking cessation in South Africa. South African Medical Journal. http://www.samj.org.za/index.php/samj/article/view/3842/2714.

21.

Klein EG, Forster JL, Erickson DJ. Longitudinal predictors of stopping smoking in young adulthood. Journal of Adolescent Health. 2013;53(3):363–7 https://doi.org/10.1016/j.jadohealth.2013.04.012.CrossRef

22.

Hays JT, Ebbert JO. Adverse effects and tolerability of medications for the treatment of tobacco use and dependence. Drugs. 2010;70(18):2357–72 https://doi.org/10.2165/11538190-000000000-00000.CrossRef

23.

Dhippayom T, Chaiyakunapruk N, Jongchansittho T. Safety of nortriptyline at equivalent therapeutic doses for smoking cessation: a systematic review and meta-analysis. Drug safety. 2011;34(3):199–210 https://doi.org/10.2165/11585950-000000000-00000.CrossRef

24.

Tian J, Venn A, Otahal P, Gall S. The association between quitting smoking and weight gain: a systemic review and meta-analysis of prospective cohort studies. Obes Rev. 2015;16(10):883–901 https://doi.org/10.1111/obr.12448.CrossRef

25.

Dare S, Mackay DF, Pell JP. Relationship between smoking and obesity: a cross-sectional study of 499,504 middle-aged adults in the UK general population. PloS one. 2015;10(4):e0123579 https://doi.org/10.1371/journal.pone.0123579.CrossRef

26.

Lowe EJ, Ackman ML. Impact of tobacco smoking cessation on stable clozapine or olanzapine treatment. Annals of Pharmacotherapy. 2010;44(4):727–32 https://doi.org/10.1345/aph.1M398.CrossRef

27.

Mottillo S, Filion KB, Belisle P, Joseph L, Gervais A, O'Loughlin J, et al. Behavioural interventions for smoking cessation: a meta-analysis of randomized controlled trials. European heart journal. 2008;30(6):718–30 https://doi.org/10.1093/eurheartj/ehn552.CrossRef

28.

Lancaster T, Stead LF. Individual behavioural counselling for smoking cessation. Cochrane database of systematic reviews. 2017;3:CD001292 https://doi.org/10.1002/14651858.CD001292.pub3.PubMed

29.

Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ (Clinical research ed). 2015;349:g7647 https://doi.org/10.1136/bmj.g7647.

30.

Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS med. 2009;6(7):e1000097 https://doi.org/10.1371/journal.pmed.1000097.CrossRef

31.

Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, et al. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. bmj. 2017;358:j4008 https://doi.org/10.1136/bmj.j4008.CrossRef

32.

Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC medical research methodology. 2007;7(1):10 https://doi.org/10.1186/1471-2288-7-10.CrossRef

33.

McHugh ML. Interrater reliability: the kappa statistic. Biochemia medica. 2012;22(3):276–82. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900052/.

34.

Aromataris E, Fernandez R, Godfrey CM, Holly C, Khalil H, Tungpunkom P. Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach. International journal of evidence-based healthcare. 2015;13(3):132–40 https://doi.org/10.1097/XEB.0000000000000055.CrossRef

35.

Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration; 2011. Available from http://handbook.cochrane.org.

36.

Pieper D, Antoine S-L, Mathes T, Neugebauer EA, Eikermann M. Systematic review finds overlapping reviews were not mentioned in every other overview. Journal of clinical epidemiology. 2014;67(4):368–75 https://doi.org/10.1016/j.jclinepi.2013.11.007.CrossRef

37.

Abbas Z, Raza S, Ejaz K. Systematic reviews and their role in evidence--informed health care. JPMA The Journal of the Pakistan Medical Association. 2008;58(10):561. http://jpma.org.pk/PdfDownload/1514.pdf.

38.

Garg AX, Hackam D, Tonelli M. Systematic review and meta-analysis: when one study is just not enough. Clinical Journal of the American Society of Nephrology. 2008;3(1):253–60 https://doi.org/10.2215/CJN.01430307.CrossRef

39.

Pieper D, Buechter RB, Li L, Prediger B, Eikermann M. Systematic review found AMSTAR, but not R (evised)-AMSTAR. to have good measurement properties. Journal of clinical epidemiology. 2015;68(5):574–83 https://doi.org/10.1016/j.jclinepi.2014.12.009.PubMed

40.

Baker PR, Costello JT, Dobbins M, Waters EB. The benefits and challenges of conducting an overview of systematic reviews in public health: a focus on physical activity. Journal of Public Health. 2014;36(3):517–21 https://doi.org/10.1093/pubmed/fdu050.CrossRef

Title: Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews
Authors: Alemu S. Melka
Catherine L. Chojenta
Elizabeth G. Holliday
Deborah J. Loxton
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Systematic Reviews / Issue 1/2018
Electronic ISSN: 2046-4053
DOI: https://doi.org/10.1186/s13643-018-0878-3

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews

Abstract

Background

Methods

Discussion

Systematic review registration

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Methods

Discussion

Systematic review registration

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