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Open Access 01-12-2022 | Aplastic Anemia | Case report

Aplastic anemia: a new complication in the recent mysterious hepatitis outbreak among children worldwide: two case reports

Authors: Ali Ghanei-Shahmirzadi, Hamid Reihani, Ali Abbasi-Kashkooli, Fereshteh Karbasian, Seyyed Bozorgmehr Hedayati, Mohammadreza Bordbar, Maryam Ataollahi, Seyed Mohsen Dehghani, Bita Geramizadeh

Published in: Journal of Medical Case Reports | Issue 1/2022

Abstract

Background

Recently, an unknown hepatitis outbreak among children has concerned many individuals worldwide. These cases are frequently reported, mainly from Europe and other countries. In this study, we present two similar patients, who, to the best of our knowledge, are the first cases reported in the Middle East (Shiraz, Fars Province, Iran). Unlike in similar cases reported up until 30 April 2022, our patients’ hepatitis eventually resulted in aplastic anemia.

Case presentation

In this study, we present cases of two Iranian boys aged 13 and 8 years with hepatitis of unknown origin who developed aplastic anemia in the course of hospitalization.

Conclusions

Hepatitis-associated aplastic anemia is a well-known immune-mediated form of aplastic anemia that we detected in our patients and treated with immunosuppressive therapy. One patient established a satisfactory response to the treatment, but unfortunately, the other was declared brain dead.

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Title: Aplastic anemia: a new complication in the recent mysterious hepatitis outbreak among children worldwide: two case reports
Authors: Ali Ghanei-Shahmirzadi
Hamid Reihani
Ali Abbasi-Kashkooli
Fereshteh Karbasian
Seyyed Bozorgmehr Hedayati
Mohammadreza Bordbar
Maryam Ataollahi
Seyed Mohsen Dehghani
Bita Geramizadeh
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Aplastic Anemia
Hepatitis
Published in: Journal of Medical Case Reports / Issue 1/2022
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-022-03542-0

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Aplastic anemia: a new complication in the recent mysterious hepatitis outbreak among children worldwide: two case reports

Abstract

Background

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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