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Journal of Medical Case Reports

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Open Access 01-12-2022 | Anticoagulant | Case report

Cerebral vein thrombosis in a woman using oral contraceptive pills for a short period of time: a case report

Authors: Somayeh Moeindarbari, Nazanin Beheshtian, Shima Hashemi

Published in: Journal of Medical Case Reports | Issue 1/2022

Abstract

Background

Cerebral vein thrombosis is increasing in young adults. Although oral contraceptive pills increase the risk of cerebral vein thrombosis, relatively high brain venous involvement is rare when oral contraceptive pills are consumed for a short duration.

Case presentation

A 31-year-old Asian woman was referred to Imam Reza Hospital with a headache complaint on 11 November 2020. The woman, who had a headache for the previous 11 days, went to the hospital. Owing to endometriosis involvement, she consumed Diane tablets. According to the imaging findings, three vein involvements were diagnosed. Anticoagulant therapy was started, and the symptoms disappeared.

Conclusions

All cerebral vein thrombosis symptoms are variable, but new presentation of headache could be an early symptom of cerebral vein thrombosis.

Khomand P, Hassanzadeh K. A case-series study of cerebral venous thrombosis in women using short course oral contraceptive. Iran J Neurol. 2016;15(2):92.PubMedPubMedCentral

Ferro JM, Canhão P, de Sousa DA. Cerebral venous thrombosis. La Presse Médicale. 2016;45(12):e429–50.CrossRef

Ferro JM, Bousser M-G, Canhão P, Coutinho JM, Crassard I, Dentali F, et al. European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis–endorsed by the European Academy of Neurology. Eur Stroke J. 2017;2(3):195–221.CrossRef

Uemura M, Tsukamoto Y, Akaiwa Y, Watanabe M, Tazawa A, Kasahara S, et al. Cerebral venous sinus thrombosis due to oral contraceptive use: postmortem 3 T-MRI and autopsy findings. Hum Pathol Case Rep. 2016;6:32–6.CrossRef

Merz M, Kroll R, Lynen R, Bangerter K. Bleeding pattern and cycle control of a low-dose transdermal contraceptive patch compared with a combined oral contraceptive: a randomized study. Contraception. 2015;91(2):113–20.CrossRef

Pakgohar M, Malekian S. Impact of oral contraceptive pills (LDs) and condoms on women’s sexual function: a prospective study in Iran. Nurs Health. 2015. https://doi.org/10.13189/nh.2015.030203.CrossRef

Matsushima T, Akira S, Asakura H, Takeshita T. Low-dose gonadotropin-releasing hormone agonist therapy (draw-back therapy) for successful long-term management of adenomyosis associated with cerebral venous and sinus thrombosis from low-dose oral contraceptive use. Clin Exp Obstet Gynecol. 2017;44(1):143–5.CrossRef

Silvis S, Hiltunen S, Lindgren E, Jood K, Zuurbier S, Middeldorp S, et al. Cancer and risk of cerebral venous thrombosis: a case–control study. J Thromb Haemost. 2018;16(1):90–5.CrossRef

Nothnick W, Alali Z. Recent advances in the understanding of endometriosis: the role of inflammatory mediators in disease pathogenesis and treatment. F1000Research. 2016;5:186.CrossRef

10.

Vinogradova Y, Coupland C, Hippisley-Cox J. Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases. BMJ. 2015;350:h2135.CrossRef

11.

Saadatnia M, Tajmirriahi M. Hormonal contraceptives as a risk factor for cerebral venous and sinus thrombosis. Acta Neurol Scand. 2007;115(5):295–300.CrossRef

12.

Bhupathiraju SN, Grodstein F, Stampfer MJ, Willett WC, Hu FB, Manson JE. Exogenous hormone use: oral contraceptives, postmenopausal hormone therapy, and health outcomes in the Nurses’ Health Study. Am J Public Health. 2016;106(9):1631–7.CrossRef

13.

Roethlisberger M, Gut L, Zumofen DW, Fisch U, Boss O, Maldaner N, et al. Cerebral venous thrombosis requiring invasive treatment for elevated intracranial pressure in women with combined hormonal contraceptive intake: risk factors, anatomical distribution, and clinical presentation. Neurosurg Focus. 2018;45(1):E12.CrossRef

14.

Dunselman G, Vermeulen N, Becker C, Calhaz-Jorge C, D’Hooghe T, De Bie B, et al. ESHRE guideline: management of women with endometriosis. Hum Reprod. 2014;29(3):400–12.CrossRef

15.

Panos GD, Panos LD, Digklia A, Hafezi F, Gatzioufas Z. Unusual presentation of cerebral venous sinus thrombosis associated with contraceptive usage. J Ophthalmic Vis Res. 2014;9(2):281.PubMedPubMedCentral

Title: Cerebral vein thrombosis in a woman using oral contraceptive pills for a short period of time: a case report
Authors: Somayeh Moeindarbari
Nazanin Beheshtian
Shima Hashemi
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Anticoagulant
Endometriosis
Thrombosis
Headache
Published in: Journal of Medical Case Reports / Issue 1/2022
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-022-03473-w

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Cerebral vein thrombosis in a woman using oral contraceptive pills for a short period of time: a case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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