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Published in: Journal of Medical Case Reports 1/2021

Open Access 01-12-2021 | Coronavirus | Case report

Extensive bilateral diffuse infiltrates and deterioration of lung following infection with severe acute respiratory syndrome coronavirus 2 in a pregnant woman: a case report

Authors: Somayeh Moeindarbary, Salmeh Dadgar, Parvaneh Layegh, Zahra Shahriari, Faezeh Fayyaz, Sina Danesteh, Mahdi Rafiee, Milad Bahrami

Published in: Journal of Medical Case Reports | Issue 1/2021

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Abstract

Introduction

Severe acute respiratory syndrome coronavirus 2 is the third member of the coronavirus family to cause global concern in the twenty-first century. Pregnant women are particularly at higher risk of developing severe viral pneumonia, possibly because of a partial immune suppression during their pregnancy. Under such critical and rapidly evolving circumstances, these poor findings might be helpful for the treatment of infected pregnant women with the 2019 novel coronavirus.

Case presentation

In this study, we report the case of a 33-year-old Asian pregnant woman at 25 gestational weeks with coronavirus disease 2019 who developed severe complications, including hypoxemia, acute respiratory distress syndrome, pulmonary infiltration, and bilateral pleural effusion. She died 1 month after admission to the hospital.

Conclusion

Pregnant populations are especially at higher risk of viral pneumonia development caused by severe acute respiratory syndrome coronavirus 2. Further research on the prevention and treatment of the new coronavirus is necessary.
Literature
1.
go back to reference Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–33.CrossRef Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727–33.CrossRef
3.
go back to reference Zhong K, Wang RX, Qian XD, Yu P, Zhu XY, Zhang Q, et al. Neuroprotective effects of saffron on the late cerebral ischemia injury through inhibiting astrogliosis and glial scar formation in rats. Biomed Pharmacother. 2020;126:110041.CrossRef Zhong K, Wang RX, Qian XD, Yu P, Zhu XY, Zhang Q, et al. Neuroprotective effects of saffron on the late cerebral ischemia injury through inhibiting astrogliosis and glial scar formation in rats. Biomed Pharmacother. 2020;126:110041.CrossRef
4.
go back to reference Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.CrossRef Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.CrossRef
5.
go back to reference Nie S, Han S, Ouyang H, Zhang Z. Coronavirus disease 2019-related dyspnea cases difficult to interpret using chest computed tomography. Respir Med. 2020;167:105951.CrossRef Nie S, Han S, Ouyang H, Zhang Z. Coronavirus disease 2019-related dyspnea cases difficult to interpret using chest computed tomography. Respir Med. 2020;167:105951.CrossRef
6.
go back to reference Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 2020;222:521.CrossRef Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A, et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 2020;222:521.CrossRef
7.
go back to reference Kareva I. Immune suppression in pregnancy and cancer: parallels and insights. Transl Oncol. 2020;13(7):100759.CrossRef Kareva I. Immune suppression in pregnancy and cancer: parallels and insights. Transl Oncol. 2020;13(7):100759.CrossRef
8.
go back to reference Visscher HC, Visscher RD. Indirect obstetric deaths in the state of Michigan 1960–1968. Am J Obstet Gynecol. 1971;109(8):1187–96.CrossRef Visscher HC, Visscher RD. Indirect obstetric deaths in the state of Michigan 1960–1968. Am J Obstet Gynecol. 1971;109(8):1187–96.CrossRef
9.
go back to reference Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12(2):194.CrossRef Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12(2):194.CrossRef
10.
go back to reference Gottfredsson M. [The Spanish flu in Iceland 1918. Lessons in medicine and history]. Laeknabladid. 2008;94(11):737–45.PubMed Gottfredsson M. [The Spanish flu in Iceland 1918. Lessons in medicine and history]. Laeknabladid. 2008;94(11):737–45.PubMed
11.
go back to reference Schwartz DA, Graham AL. Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12(2):194.CrossRef Schwartz DA, Graham AL. Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses. 2020;12(2):194.CrossRef
12.
go back to reference Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(5):559–64.CrossRef Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X, et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis. 2020;20(5):559–64.CrossRef
13.
go back to reference Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–15.CrossRef Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809–15.CrossRef
14.
go back to reference Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020;223:111.CrossRef Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 in pregnant women: a report based on 116 cases. Am J Obstet Gynecol. 2020;223:111.CrossRef
15.
go back to reference Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, et al. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis. AJR Am J Roentgenol. 2020;215(1):127–32.CrossRef Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, et al. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis. AJR Am J Roentgenol. 2020;215(1):127–32.CrossRef
16.
go back to reference Devasenapathy N, Ye Z, Loeb M, Fang F, Najafabadi BT, Xiao Y, et al. Efficacy and safety of convalescent plasma for severe COVID-19 based on evidence in other severe respiratory viral infections: a systematic review and meta-analysis. CMAJ. 2020;197:E745–55.CrossRef Devasenapathy N, Ye Z, Loeb M, Fang F, Najafabadi BT, Xiao Y, et al. Efficacy and safety of convalescent plasma for severe COVID-19 based on evidence in other severe respiratory viral infections: a systematic review and meta-analysis. CMAJ. 2020;197:E745–55.CrossRef
17.
go back to reference Sadeghnia HR, Shaterzadeh H, Forouzanfar F, Hosseinzadeh H. Neuroprotective effect of safranal, an active ingredient of Crocus sativus, in a rat model of transient cerebral ischemia. Folia Neuropathol. 2017;55(3):206–13.CrossRef Sadeghnia HR, Shaterzadeh H, Forouzanfar F, Hosseinzadeh H. Neuroprotective effect of safranal, an active ingredient of Crocus sativus, in a rat model of transient cerebral ischemia. Folia Neuropathol. 2017;55(3):206–13.CrossRef
18.
go back to reference Alzamora MC, Paredes T, Caceres D, Webb CM, Valdez LM, La Rosa M. Severe COVID-19 during pregnancy and possible vertical transmission. Am J Perinatol. 2020;37:861–5.CrossRef Alzamora MC, Paredes T, Caceres D, Webb CM, Valdez LM, La Rosa M. Severe COVID-19 during pregnancy and possible vertical transmission. Am J Perinatol. 2020;37:861–5.CrossRef
19.
go back to reference Baud D, Greub G, Favre G, Gengler C, Jaton K, Dubruc E, et al. Second-trimester miscarriage in a pregnant woman with SARS-CoV-2 infection. JAMA. 2020;323:2198.CrossRef Baud D, Greub G, Favre G, Gengler C, Jaton K, Dubruc E, et al. Second-trimester miscarriage in a pregnant woman with SARS-CoV-2 infection. JAMA. 2020;323:2198.CrossRef
20.
go back to reference Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, et al. Maternal death due to COVID-19 disease. Am J Obstet Gynecol. 2020;223:109.e1.CrossRef Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, et al. Maternal death due to COVID-19 disease. Am J Obstet Gynecol. 2020;223:109.e1.CrossRef
22.
go back to reference Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020;99:823–9.CrossRef Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020;99:823–9.CrossRef
23.
go back to reference Castro P, Matos AP, Werner H, Lopes FP, Tonni G, Araujo JE. Covid-19 and pregnancy: an overview. Rev Bras Ginecol Obstet. 2020;42(7):420–6.CrossRef Castro P, Matos AP, Werner H, Lopes FP, Tonni G, Araujo JE. Covid-19 and pregnancy: an overview. Rev Bras Ginecol Obstet. 2020;42(7):420–6.CrossRef
Metadata
Title
Extensive bilateral diffuse infiltrates and deterioration of lung following infection with severe acute respiratory syndrome coronavirus 2 in a pregnant woman: a case report
Authors
Somayeh Moeindarbary
Salmeh Dadgar
Parvaneh Layegh
Zahra Shahriari
Faezeh Fayyaz
Sina Danesteh
Mahdi Rafiee
Milad Bahrami
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2021
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-021-03156-y

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