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Published in: Journal of Medical Case Reports 1/2021

Open Access 01-12-2021 | Suicide | Case report

Suicidal attempt with caffeine overdose treated with dexmedetomidine: a case report

Authors: Teppei Kitano, Masaki Okajima, Koji Sato, Toru Noda, Takumi Taniguchi

Published in: Journal of Medical Case Reports | Issue 1/2021

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Abstract

Background

Caffeine is a widely used dietary stimulant, and cases of caffeine overdoses, sometimes leading to death, are increasing. We encountered a case of caffeine intoxication resolved with administration of the sedative agent dexmedetomidine.

Case presentation

We administered dexmedetomidine for sedation and to suppress sympathetic nerve stimulation in the case of an 18-year-old Japanese male who ingested a massive dose of caffeine with the intention of committing suicide. The patient was in an excited state and had hypertension, sinus tachycardia, and hypokalemia with prominent QT prolongation. After dexmedetomidine administration, the patient’s mental state, hemodynamics, and electrolyte levels were improved immediately. He was discharged without any sequelae 3 days later.

Conclusion

Cases of acute caffeine intoxication with agitation, sympathetic overactivity and adverse cardiac events would benefit with dexmedetomidine treatment.
Literature
1.
go back to reference Kamijo Y, Takai M, Fujita Y, Usui K. A retrospective study on the epidemiological and clinical features of emergency patients with large or massive consumption of caffeinated supplements or energy drinks in Japan. Intern Med. 2018;57(15):2141–6.CrossRef Kamijo Y, Takai M, Fujita Y, Usui K. A retrospective study on the epidemiological and clinical features of emergency patients with large or massive consumption of caffeinated supplements or energy drinks in Japan. Intern Med. 2018;57(15):2141–6.CrossRef
2.
go back to reference Ishikawa T, Yuasa I, Endoh M. Non specific drug distribution in an autopsy case report of fatal caffeine intoxication. Leg Med (Tokyo). 2015;17(6):535–8.CrossRef Ishikawa T, Yuasa I, Endoh M. Non specific drug distribution in an autopsy case report of fatal caffeine intoxication. Leg Med (Tokyo). 2015;17(6):535–8.CrossRef
3.
go back to reference Panzer O, Moitra V, Sladen RN. Pharmacology of sedative-analgesic agents: Dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists. Anesthesiology clinics, vol 29. Elsevier; 2011. p. 587–605. Panzer O, Moitra V, Sladen RN. Pharmacology of sedative-analgesic agents: Dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists. Anesthesiology clinics, vol 29. Elsevier; 2011. p. 587–605.
5.
go back to reference Echeverri D, Montes FR, Cabrera M, Galán A, Prieto A. Caffeine’s vascular mechanisms of action. Int J Vasc Med. 2010;2010:1–10.CrossRef Echeverri D, Montes FR, Cabrera M, Galán A, Prieto A. Caffeine’s vascular mechanisms of action. Int J Vasc Med. 2010;2010:1–10.CrossRef
9.
go back to reference Higdon JV, Frei B. Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr. 2006;46(2):101–23.CrossRef Higdon JV, Frei B. Coffee and health: a review of recent human research. Crit Rev Food Sci Nutr. 2006;46(2):101–23.CrossRef
10.
go back to reference Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev. 2019;17(2):139–70.CrossRef Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev. 2019;17(2):139–70.CrossRef
Metadata
Title
Suicidal attempt with caffeine overdose treated with dexmedetomidine: a case report
Authors
Teppei Kitano
Masaki Okajima
Koji Sato
Toru Noda
Takumi Taniguchi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2021
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-020-02611-6

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