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Published in: Journal of Medical Case Reports 1/2018

Open Access 01-12-2018 | Case report

En bloc corpectomy for late gastrointestinal stromal tumor metastasis: a case report and review of the literature

Authors: Takaki Shimizu, Hideki Murakami, Apiruk Sangsin, Satoru Demura, Satoshi Kato, Kazuya Shinmura, Noriaki Yokogawa, Norihiro Oku, Ryo Kitagawa, Hiroyuki Tsuchiya

Published in: Journal of Medical Case Reports | Issue 1/2018

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Abstract

Background

Spinal metastases of gastrointestinal stromal tumors are rare; however, the incidence has been increasing since the introduction of tyrosine kinase inhibitors, which have improved overall survival. Due to the rarity of cases, there are no treatment guidelines for spinal metastases of gastrointestinal stromal tumors. We describe a patient who underwent spinal metastasectomy for a rectal gastrointestinal stromal tumor; we further provide a review of all cases of gastrointestinal stromal tumors with spinal metastases.

Case presentation

A 51-year-old Japanese man who had undergone resection for a rectal gastrointestinal stromal tumor was diagnosed with L3 vertebral metastasis 10 years after surgery. As there were no metastases to vital organs, an en bloc corpectomy of the L3 vertebral body, using bilateral retroperitoneal approaches, was performed to achieve local cure and to prevent neural compression. A 3-year follow-up showed no local recurrence or new metastases; he had full neurological function.

Conclusions

Spinal metastasectomy can be an effective treatment for solitary spinal metastases of gastrointestinal stromal tumors.
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Metadata
Title
En bloc corpectomy for late gastrointestinal stromal tumor metastasis: a case report and review of the literature
Authors
Takaki Shimizu
Hideki Murakami
Apiruk Sangsin
Satoru Demura
Satoshi Kato
Kazuya Shinmura
Noriaki Yokogawa
Norihiro Oku
Ryo Kitagawa
Hiroyuki Tsuchiya
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2018
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-018-1844-3

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