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Open Access 01-12-2018 | Case report

Multiple myeloma concealed by adrenal Cushing syndrome: a case report and review of the literature

Authors: Taweesak Wannachalee, Nuttagarn Jantanapornchai, Kittima Suphadirekkul, Sirinart Sirinvaravong, Weerapat Owattanapanich

Published in: Journal of Medical Case Reports | Issue 1/2018

Abstract

Background

Cushing syndrome coexisting with multiple myeloma has been previously described in a few reports. Overlapping clinical manifestations can lead to misdiagnoses.

Case presentation

We presented an extremely rare case of a 33-year-old Thai woman with concomitant kappa light chain myeloma with adrenal Cushing syndrome, both of which were related to skeletal manifestations. A precedence report indicated that treatment of the Cushing syndrome could exacerbate the myeloma symptoms. Therefore, we were faced with the dilemma of which disease should be addressed first. We decided to treat our patient with a combination chemotherapy followed by an autologous stem cell transplant. Subsequently, a left laparoscopic adrenalectomy was successfully undertaken.

Conclusion

We have reported the first association between adrenocorticotropic hormone-independent Cushing syndrome resulting from a left autonomous cortisol-secreting adrenal adenoma, and multiple myeloma.

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Title: Multiple myeloma concealed by adrenal Cushing syndrome: a case report and review of the literature
Authors: Taweesak Wannachalee
Nuttagarn Jantanapornchai
Kittima Suphadirekkul
Sirinart Sirinvaravong
Weerapat Owattanapanich
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2018
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-018-1731-y

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Multiple myeloma concealed by adrenal Cushing syndrome: a case report and review of the literature

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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