Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2018

Open Access 01-12-2018 | Case report

Giant congenital melanocytic nevus in a Cameroonian child: a case report

Authors: Francky Teddy Endomba, Charlie Romain Mbega, Joel Noutakdie Tochie, Saint-Just N. Petnga

Published in: Journal of Medical Case Reports | Issue 1/2018

Login to get access

Abstract

Background

Giant congenital melanocytic nevus is a very rare condition characterized by a large skin lesion and an increased risk of complications like neurocutaneous melanosis and malignant transformation. Reports of giant congenital melanocytic nevus are scarce in the sub-Saharan African literature and here we present a case of this disease in a Cameroonian adolescent.

Case presentation

A 12-year-old Cameroonian girl from the "Baka" ethnic group, with no relevant family and medical histories presented with a progressively extensive brownish-black nodular hypertrophic skin lesion of approximately 45 cm, which she had had since she was 2-days old. The lesion covered her entire back giving an appearance of “turtle child”, which was highly suggestive of a giant congenital melanocytic nevus. She was booked in for a surgical intervention organized by a health campaign within her community. Meanwhile she was provided with psychological support and her family was counseled on warning signs of complications which would warrant an urgent consultation.

Conclusions

Here we presented a case of giant congenital melanocytic nevus, apparently the first in the Cameroonian literature. In view of the potential severe complications as well as psychological trauma of this pathology, we draw clinicians’ attention to this extremely rare but real pathology in our country, for a timely diagnosis and management.
Literature
1.
go back to reference Grichnik JM, Rhodes AR, Sober AJ. Benign neoplasias and hyperplasias of melanocytes. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Lefell DJ, editors. Fitzpatrick’s Dermatology in General Medicine. 7th ed. New York: McGraw-Hill; 2008. p. 1099–122. Grichnik JM, Rhodes AR, Sober AJ. Benign neoplasias and hyperplasias of melanocytes. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Lefell DJ, editors. Fitzpatrick’s Dermatology in General Medicine. 7th ed. New York: McGraw-Hill; 2008. p. 1099–122.
3.
go back to reference Kopf A, Bart R, Hennessey P. Congenital nevocytic nevi and malignant melanomas. J Am Acad Dermatol. 1979;1:123–30.CrossRefPubMed Kopf A, Bart R, Hennessey P. Congenital nevocytic nevi and malignant melanomas. J Am Acad Dermatol. 1979;1:123–30.CrossRefPubMed
5.
go back to reference Slutsky JB, Barr JM, Femia AN, Marghoob AA. Large congenital melanocytic nevi: associated risks and management considerations. Semin Cutan Med Surg. 2010;29(2):79–84.CrossRefPubMed Slutsky JB, Barr JM, Femia AN, Marghoob AA. Large congenital melanocytic nevi: associated risks and management considerations. Semin Cutan Med Surg. 2010;29(2):79–84.CrossRefPubMed
6.
go back to reference Koot HM, de Waard-van der Spek F, Peer CD, Mulder PG, Oranje AP. Psychosocial sequelae in 29 children with giant congenital melanocytic naevi. Clin Exp Dermatol. 2000;25:589–93.CrossRefPubMed Koot HM, de Waard-van der Spek F, Peer CD, Mulder PG, Oranje AP. Psychosocial sequelae in 29 children with giant congenital melanocytic naevi. Clin Exp Dermatol. 2000;25:589–93.CrossRefPubMed
7.
go back to reference Imchen S, Ghosh S, Dayal S, Marwah N, Jindal N, Sangal S. Giant Congenital Melanocytic Nevus with Developmental Dysplasia of Bilateral Hip: A Rare Association. Indian J Dermatol. 2013;58(6):475–7.CrossRefPubMedPubMedCentral Imchen S, Ghosh S, Dayal S, Marwah N, Jindal N, Sangal S. Giant Congenital Melanocytic Nevus with Developmental Dysplasia of Bilateral Hip: A Rare Association. Indian J Dermatol. 2013;58(6):475–7.CrossRefPubMedPubMedCentral
8.
go back to reference Krengel S, Hauschild A, Schäfer T. Melanoma risk in congenital melanocytic naevi: a systematic review. Br J Dermatol. 2006;155(1):1–8.CrossRefPubMed Krengel S, Hauschild A, Schäfer T. Melanoma risk in congenital melanocytic naevi: a systematic review. Br J Dermatol. 2006;155(1):1–8.CrossRefPubMed
9.
go back to reference Kinsler VA, Birley J, Atherton DJ. Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1- epidemiology, phenotype and outcomes. Br J Dermatol. 2009;160:143–50.CrossRefPubMed Kinsler VA, Birley J, Atherton DJ. Great Ormond Street Hospital for Children Registry for congenital melanocytic naevi: prospective study 1988-2007. Part 1- epidemiology, phenotype and outcomes. Br J Dermatol. 2009;160:143–50.CrossRefPubMed
11.
go back to reference Charbel C, Fontaine RH, Malouf GG, Picard A, Kadlub N, El-Murr N, et al. NRAS Mutation Is the Sole Recurrent Somatic Mutation in Large Congenital Melanocytic Nevi. J Invest Dermatol. 2014;134(4):1067–74.CrossRefPubMed Charbel C, Fontaine RH, Malouf GG, Picard A, Kadlub N, El-Murr N, et al. NRAS Mutation Is the Sole Recurrent Somatic Mutation in Large Congenital Melanocytic Nevi. J Invest Dermatol. 2014;134(4):1067–74.CrossRefPubMed
12.
go back to reference Gowda VK, Basude A, Srinivas SM, Bhat M. Giant melanocytic nevi with neurocutaneous melanosis masquerading as neurofibromas. J Pediatr Neurosci. 2016;11(3):258–60.CrossRefPubMedPubMedCentral Gowda VK, Basude A, Srinivas SM, Bhat M. Giant melanocytic nevi with neurocutaneous melanosis masquerading as neurofibromas. J Pediatr Neurosci. 2016;11(3):258–60.CrossRefPubMedPubMedCentral
13.
go back to reference Newton Bishop JA. Lentigos, melanocytic naevi and melanoma. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook’s Textbook of Dermatology. 8th ed. London: Blackwell Science; 2010. Chapter 54, p. 1–57. Newton Bishop JA. Lentigos, melanocytic naevi and melanoma. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook’s Textbook of Dermatology. 8th ed. London: Blackwell Science; 2010. Chapter 54, p. 1–57.
14.
go back to reference Simons EA, Huang JT, Schmidt B. Congenital melanocytic nevi in young children: Histopathologic features and clinical outcomes. J Am Acad Dermatol. 2017;76(5):941–7.CrossRefPubMed Simons EA, Huang JT, Schmidt B. Congenital melanocytic nevi in young children: Histopathologic features and clinical outcomes. J Am Acad Dermatol. 2017;76(5):941–7.CrossRefPubMed
15.
go back to reference Price HN. Congenital melanocytic nevi: update in genetics and management. Curr Opin Pediatr. 2016;28(4):476–82.CrossRefPubMed Price HN. Congenital melanocytic nevi: update in genetics and management. Curr Opin Pediatr. 2016;28(4):476–82.CrossRefPubMed
Metadata
Title
Giant congenital melanocytic nevus in a Cameroonian child: a case report
Authors
Francky Teddy Endomba
Charlie Romain Mbega
Joel Noutakdie Tochie
Saint-Just N. Petnga
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2018
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-018-1707-y

Other articles of this Issue 1/2018

Journal of Medical Case Reports 1/2018 Go to the issue