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Open Access 01-12-2018 | Editorial

Methotrexate: who would have predicted its importance in rheumatoid arthritis?

Author: Michael E. Weinblatt

Published in: Arthritis Research & Therapy | Issue 1/2018

Excerpt

Forty years ago, the US Food and Drug Administration approved low dose methotrexate (MTX) for the treatment of active rheumatoid arthritis (RA). MTX was previously approved for a variety of malignancies at high doses and at low doses for psoriasis. Little did one anticipate in 1988 that MTX would change the course of RA. I had the pleasure of being directly involved in the development of MTX in RA and it has been extremely gratifying to see the impact of MTX in RA. …

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Title: Methotrexate: who would have predicted its importance in rheumatoid arthritis?
Author: Michael E. Weinblatt
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Arthritis Research & Therapy / Issue 1/2018
Electronic ISSN: 1478-6362
DOI: https://doi.org/10.1186/s13075-018-1599-7

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