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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2016

Open Access 01-12-2016 | Letter

Response to: ‘A dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine’

Authors: Kaj S. Emanuel, Idsart Kingma, Marco N. Helder, Theodoor H. Smit

Published in: Arthritis Research & Therapy | Issue 1/2016

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Excerpt

With much interest we read the recent paper by Teichtahl et al. [1], who gave novel insight into the association between disc degeneration and intervertebral disc height. The current golden standard, the Pfirrmann Score, has a good internal validity. However, its subjective nature, low discriminative power, and moderate relation to physiological and clinical parameters have inspired many investigators to search for a better alternative. We support this enthusiastically, as there is a great need for a measure with higher clinical relevance. …
Literature
1.
Teichtahl AJ, Urquhart DM, Wang Y, Wluka AE, Heritier S, Cicuttini FM. A dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine. Arthritis Res Ther. 2015;17:297.PubMedCentralCrossRefPubMed
2.
Emanuel KS, Vergroesen PA, Peeters M, Holewijn RM, Kingma I, Smit TH. Poroelastic behaviour of the degenerating human intervertebral disc: a ten-day study in a loaded disc culture system. Eur Cell Mater. 2015;29:330–41.PubMed
3.
Botsford DJ, Esses SI, Ogilvie-Harris DJ. In vivo diurnal variation in intervertebral disc volume and morphology. Spine (Phila Pa 1976). 1994;19:935–40.CrossRef
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Videman T, Battié M, Gibbons L. Associations between back pain history and lumbar MRI findings. Spine (Phila Pa 1976). 2003;28:582–8.
5.
Johannessen W, Auerbach JD, Wheaton AJ, Kurji A, Borthakur A, Reddy R, et al. Assessment of human disc degeneration and proteoglycan content using T1rho-weighted magnetic resonance imaging. Spine (Phila Pa 1976). 2006;31:1253–7.CrossRef
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Welsch GH, Trattnig S, Paternostro-Sluga T, Bohndorf K, Goed S, Stelzeneder D, et al. Parametric T2 and T2* mapping techniques to visualize intervertebral disc degeneration in patients with low back pain: initial results on the clinical use of 3.0 Tesla MRI. Skeletal Radiol. 2011;40:543–51.CrossRefPubMed
Metadata
Title
Response to: ‘A dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine’
Authors
Kaj S. Emanuel
Idsart Kingma
Marco N. Helder
Theodoor H. Smit
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue 1/2016
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/s13075-016-0944-y

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