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Published in: Trials 1/2019

Open Access 01-12-2019 | Contraception | Research

A randomized controlled trial of an intervention delivered by mobile phone text message to increase the acceptability of effective contraception among young women in Palestine

Authors: Ona L. McCarthy, Hanadi Zghayyer, Amina Stavridis, Samia Adada, Irrfan Ahamed, Baptiste Leurent, Phil Edwards, Melissa Palmer, Caroline Free

Published in: Trials | Issue 1/2019

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Abstract

Background

Research has shown that mobile phone contraceptive behavioral interventions can increase knowledge and use of contraception, but other studies have failed to demonstrate a beneficial effect. The objective of this trial was to estimate the effect of a contraceptive behavioral intervention delivered by mobile phone text message on young Palestinian women’s attitudes towards effective contraception.

Methods

We conducted a randomized controlled trial among women aged 18–24 years living in the West Bank, who were not using an effective method of contraception. The intervention group received zero to three messages per day (113 messages for female-not married and 120 messages for female-married) for 120 days. The control group received 16 messages over 120 days about trial participation. The primary outcome was acceptability of at least one method of effective contraception at 4 months. Secondary outcomes were use of effective contraception at 4 months and any use during the study, acceptability of individual methods, service uptake, unintended pregnancy and abortion. Process outcomes included knowledge, perceived norms, personal agency and intention. All outcomes were self-reported. We analyzed the outcomes using logistic and linear regression.

Results

A total of 578 participants were enrolled and 464 (80%) completed follow up at 4 months. Intervention group participants were more likely to find at least one method of effective contraception acceptable (31% in the intervention group versus 17% in the control group, adjusted OR 2.34, 95% CI 1.48–3.68, p < 0.001). They had a higher mean knowledge score, were more likely to find the intrauterine device, injection, implant and patch acceptable, to agree that their friends would use an effective method and to intend to use an effective method, compared to participants in the control group. While in the direction of intervention benefit, there were no differences between the groups in the use of effective contraception at 4 months and any use during the study, pill acceptability, service uptake, unintended pregnancy and induced abortion.

Conclusions

The intervention can improve attitudes, knowledge-perceived norms and intention to use effective contraception among young women in Palestine. Research is needed to evaluate the efficacy of the intervention for contraceptive behavioral outcomes in Palestine.

Trial registration

ClinicalTrials.gov, NCT02905461. Registered on 14 September 2016.
Appendix
Available only for authorised users
Literature
1.
Sedgh G, Singh S, Hussain R. Intended and unintended pregnancies worldwide in 2012 and recent trends. Stud Fam Plan. 2014;45(3):301–14.CrossRef
2.
Darroch JE, et al. Adding it up: Investing in Contraception and Maternal and Newborn Health. New York: Guttmacher Institute; 2017.
3.
Singh S, Darroch J, Ashford L. Adding it up: the costs and benefits of investing in sexual and reproductive health 2014. New York: Guttmacher Institute; 2014.
4.
Sedgh G, Ashford L, Hussain R. Unmet need for contraception in developing countries: examining women’s reasons for not using a method. New York: Guttmacher Institute; 2016.
5.
Bosmans M, Nasser D, Khammash U, Claeys P, Temmerman M. Palestinian women’s sexual and reproductive health rights in a longstanding humanitarian crisis. Reprod Health Matters. 2008;16(31):103–11.CrossRefPubMedCentral
6.
Giacaman R, Abu-Rmeileh NME, Mataria A, Wick L. Palestinian women’s pregnancy intentions: analysis and critique of the Demographic and Health Survey 2004. Health Policy. 2008;85(1):83–93.CrossRef
7.
Roudi-Fahimi F, Abdul Monem A. Unintended pregnancies in the Middle East and North Africa. WashingtonDC: Population Reference Bureau; 2010.
8.
Palestinian Central Bureau of Statistics. Palestinian Multiple Indicator Cluster Survey, 2014, Final Report. Ramallah: PCBS; 2015.
9.
Courbage Y, Abu Hamad B, Zagha A. Palestine 2030- Demographic change: opportunities for development. State of Palestine: State of Palestine & United Nations Population Fund; 2016.
10.
Palestinian Central Bureau of Statistics. Final report of the Palestinian Family Survey 2010. Ramallah: PCBS; 2013.
11.
Hammoudeh W. Addressing family planning delivery gaps in the Palestinian Territory. Washington, DC: Population Reference Bureau; 2014.
12.
Orr JA, King RJ. Mobile phone SMS messages can enhance healthy behaviour: a meta-analysis of randomised controlled trials. Health Psychol Rev. 2015;9(4):397–416.CrossRef
13.
Hall CS, Fottrell E, Wilkinson S, Byass P. Assessing the impact of mHealth interventions in low- and middle-income countries–what has been shown to work? Glob Health Action. 2014;7:25606.CrossRef
14.
Aranda-Jan CB, Mohutsiwa-Dibe N, Loukanova S. Systematic review on what works, what does not work and why of implementation of mobile health (mHealth) projects in Africa. BMC Public Health. 2014;14:188.CrossRefPubMedCentral
15.
Free C, Phillips G, Galli L, Watson L, Felix L, Edwards P, et al. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review. PLoS Med. 2013;10(1):e1001362.CrossRefPubMedCentral
16.
Head KJ, Noar SM, Iannarino NT, Grant Harrington N. Efficacy of text messaging-based interventions for health promotion: a meta-analysis. Soc Sci Med. 2013;97:41–8.CrossRef
17.
Hall AK, Cole-Lewis H, Bernhardt JM. Mobile text messaging for health: a systematic review of reviews. Annu Rev Public Health. 2015;36:393–415.CrossRefPubMedCentral
18.
L’Engle KL, Mangone ER, Parcesepe AM, Agarwal S, Ippoliti NB. Mobile phone interventions for adolescent sexual and reproductive health: a systematic review. Pediatrics. 2016;138(3):e20160884.CrossRef
19.
Sayej S, Kokian V. Increasing access of the underserved areas in Palestine to SRH services; 2014.
20.
Castaño PM, Bynum JY, Andres R, Lara M, Westhoff C. Effect of daily text messages on oral contraceptive continuation: a randomized controlled trial. Obstet Gynecol. 2012;119(1):14–20.CrossRefPubMedCentral
21.
Harrington E. Evaluation of an mHealth SMS dialogue strategy to meet women’s and couples’ postpartum contraceptive needs in Kenya (Mobile WACh XY): a randomized controlled trial; 2018.
22.
Smith C, Ngo TD, Gold J, Edwards P, Vannak U, Sokhey L, et al. Effect of a mobile phone-based intervention on post-abortion contraception: a randomized controlled trial in Cambodia. Bull World Health Organ. 2015;93:842–850A.CrossRefPubMedCentral
23.
Hebert LE, Hill BJ, Quinn M, Holl JL, Whitaker AK, Gilliam ML. Mobile contraceptive application use in a clinical setting in addition to standard contraceptive counseling: a randomized controlled trial. Contraception. 2018;98:281–7.CrossRefPubMedCentral
24.
Johnson D, Juras R, Riley P, Chatterji M, Sloane P, Choi SK, et al. A randomized controlled trial of the impact of a family planning mHealth service on knowledge and use of contraception. Contraception. 2017;95(1):90–7.CrossRefPubMedCentral
25.
Rokicki S, Cohen J, Salomon JA, Fink G. Impact of a text-messaging program on adolescent reproductive health: a cluster-randomized trial in Ghana. Am J Public Health. 2017;107(2):298–305.CrossRefPubMedCentral
26.
Bull S, Devine S, Schmiege SJ, Pickard L, Campbell J, Shlay JC. Text messaging, teen outreach program, and sexual health behavior: a cluster randomized trial. Am J Public Health. 2016;106(S1):S117–S24.CrossRefPubMedCentral
27.
Hou MY, Hurwitz S, Kavanagh E, Fortin J, Goldberg AB. Using daily text-message reminders to improve adherence with oral contraceptives: a randomized controlled trial. [Erratum appears in Obstet Gynecol. 2010 Nov;116(5):1224]. Obstet Gynecol. 2010;116(3):633–40.CrossRefPubMedCentral
28.
Trent M, Thompson C, Tomaszewski K. Text messaging support for urban adolescents and Young adults using injectable contraception: outcomes of the DepoText pilot trial. J Adolescent Health. 2015;57(1):100–6.CrossRef
29.
Tsur L, Kozer E, Berkovitch M. The effect of drug consultation center guidance on contraceptive use among women using isotretinoin: a randomized, controlled study. J Womens Health. 2008;17(4):579–84.CrossRef
30.
Sridhar A, Chen A, Forbes ER, Glik D. Mobile application for information on reversible contraception: a randomized controlled trial. Am J Obstet Gynecol. 2015;212(6):774 e1–7.CrossRef
31.
McCarthy OL, Wazwaz O, Osorio Calderon V, Jado I, Saibov S, Stavridis A, et al. Development of an intervention delivered by mobile phone aimed at decreasing unintended pregnancy among young people in three lower middle income countries. BMC Public Health. 2018;18(1):576.CrossRefPubMedCentral
32.
McCarthy OL, Wazwaz O, Jado I, Leurent B, Edwards P, Adada S, et al. An intervention delivered by text message to increase the acceptability of effective contraception among young women in Palestine: study protocol for a randomised controlled trial. Trials. 2017;18(1):454.CrossRefPubMedCentral
33.
34.
Cleland J, Ali MM. Reproductive consequences of contraceptive failure in 19 developing countries. Obstet Gynecol. 2004;104(2):314–20.CrossRef
35.
Trussell J. Contraceptive efficacy. In: Hatcher R, Trussell J, Nelson A, Cates W, Kowal D, Policar M, editors. Contraceptive technology: twentieth revised edition. 20th ed. New York: Ardent Media; 2011.
36.
37.
Montaño D, Kasprzyk D. Theory of reasoned action, theory of planned behavior, and the integrated behavioral model. In: Glanz K, Rimer BK, Viswanath K, editors. Health behaviour: theory, research and practice. 5 ed. San Francisco: Jossey-Bass; 2015. p. 168–222.
38.
Kok G, Gottlieb N, Peters G, Mullen P, Parcel G, Ruiter R, et al. A taxonomy of behavior Change methods; an intervention mapping approach. Health Psychol Rev. 2016;10(3):297–312.CrossRef
39.
Kent DM, Rothwell PM, Ioannidis JPA, Altman DG, Hayward RA. Assessing and reporting heterogeneity in treatment effects in clinical trials: a proposal. Trials. 2010;11:85.CrossRefPubMedCentral
40.
Brookes ST, Whitely E, Egger M, Smith GD, Mulheran PA, Peters TJ. Subgroup analyses in randomized trials: risks of subgroup-specific analyses; power and sample size for the interaction test. J Clin Epidemiol. 2004;57(3):229–36.CrossRefPubMedCentral
41.
Smith C, Gold J, Ngo TD, Sumpter C, Free C. Mobile phone-based interventions for improving contraception use. Cochrane Database Syst Rev. 2015; Issue 6. Art. No.: CD011159.
42.
McCarthy O, Ahamed I, Kulaeva F, Tokhirov R, Saibov S, Vandewiele M, et al. A randomized controlled trial of an intervention delivered by mobile phone app instant messaging to increase the acceptability of effective contraception among young people in Tajikistan. Reprod Health. 2018;15(1):28.CrossRefPubMedCentral
Metadata
Title
A randomized controlled trial of an intervention delivered by mobile phone text message to increase the acceptability of effective contraception among young women in Palestine
Authors
Ona L. McCarthy
Hanadi Zghayyer
Amina Stavridis
Samia Adada
Irrfan Ahamed
Baptiste Leurent
Phil Edwards
Melissa Palmer
Caroline Free
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Contraception
Published in
Trials / Issue 1/2019
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-019-3297-4

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