Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Critical Care
Published in: Critical Care 1/2021

01-12-2021 | Acute Respiratory Distress-Syndrome | Research Letter

Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic

Authors: Christian Karagiannidis, Arthur S. Slutsky, Thomas Bein, Wolfram Windisch, Steffen Weber-Carstens, Daniel Brodie

Published in: Critical Care | Issue 1/2021

Login to get access

Excerpt

Extracorporeal membrane-oxygenation (ECMO) has been widely used for COVID-19-related acute respiratory distress syndrome (ARDS), with a mortality rate of 37.1% based on the largest published series [1]. This rate is comparable to ECMO-supported patients with non-COVID-19-related ARDS [1]. However, some reports suggest that the real-life mortality is higher than that reported above [2], including a cohort of 768 COVID-19 patients in Germany with an in-hospital mortality rate of 73% [3], and a surprising finding is given that health care resources in Germany were not notably under strain during the pandemic. To better characterize this discrepancy, we evaluated in-hospital mortality for all COVID-19 patients in Germany supported with venovenous ECMO (VV-ECMO). …
Literature
1.
Ramanathan K, Shekar K, Ling RR, et al. Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis. Crit Care. 2021;25(1):211.CrossRef
2.
Lebreton G, Schmidt M, Ponnaiah M, et al. Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study. Lancet Respir Med 2021.
3.
Karagiannidis C, Strassmann S, Merten M, et al. High in-hospital mortality in COVID patients receiving ECMO in Germany - A critical analysis. Am J Respir Crit Care Med 2021.
4.
Broman LM, Eksborg S, Coco VL, et al. Extracorporeal membrane oxygenation for COVID-19 during first and second waves. Lancet Respir Med 2021.
5.
Barbaro RP MG, Boonstra PS, Combes A, Agerstrand CL, Annich G, Diaz R, Fan E, Hryniewicz K, Lorusso R, Paden ML, Stead CM, Swol J, Iwashyna TJ, Slutsky AS, Brodie D; for the Extracorporeal Life Support Organization. Extracorporeal membrane oxygenation for COVID-19: Evolving outcomes from the international Extracorporeal Life Support Organization Registry. Lancet 2021; (in press August 19).
6.
Friedrichson B, Mutlak H, Zacharowski K, Piekarski F. Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs. Crit Care. 2021;25(1):38.CrossRef
Metadata
Title
Complete countrywide mortality in COVID patients receiving ECMO in Germany throughout the first three waves of the pandemic
Authors
Christian Karagiannidis
Arthur S. Slutsky
Thomas Bein
Wolfram Windisch
Steffen Weber-Carstens
Daniel Brodie
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2021
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-021-03831-y

Other articles of this Issue 1/2021

Critical Care 1/2021 Go to the issue

Review

Dangers of hyperoxia

Research

High-flow nasal oxygen in patients with COVID-19-associated acute respiratory failure

Research

Monocyte distribution width (MDW) performance as an early sepsis indicator in the emergency department: comparison with CRP and procalcitonin in a multicenter international European prospective study

Research

Association of inflammatory biomarkers with subsequent clinical course in suspected late onset sepsis in preterm neonates

Research Letter

Elevated HbA1c remains a predominant finding in severe COVID-19 and may be associated with increased mortality in patients requiring mechanical ventilation

Letter

Proportional assist ventilation versus pressure support ventilation for weaning from mechanical ventilation in adults: weaning success and mortality