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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Ultrasound | Review

Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus

Authors: Arif Hussain, Gabriele Via, Lawrence Melniker, Alberto Goffi, Guido Tavazzi, Luca Neri, Tomas Villen, Richard Hoppmann, Francesco Mojoli, Vicki Noble, Laurent Zieleskiewicz, Pablo Blanco, Irene W. Y. Ma, Mahathar Abd. Wahab, Abdulmohsen Alsaawi, Majid Al Salamah, Martin Balik, Diego Barca, Karim Bendjelid, Belaid Bouhemad, Pablo Bravo-Figueroa, Raoul Breitkreutz, Juan Calderon, Jim Connolly, Roberto Copetti, Francesco Corradi, Anthony J. Dean, André Denault, Deepak Govil, Carmela Graci, Young-Rock Ha, Laura Hurtado, Toru Kameda, Michael Lanspa, Christian B. Laursen, Francis Lee, Rachel Liu, Massimiliano Meineri, Miguel Montorfano, Peiman Nazerian, Bret P. Nelson, Aleksandar N. Neskovic, Ramon Nogue, Adi Osman, José Pazeli, Elmo Pereira-Junior, Tomislav Petrovic, Emanuele Pivetta, Jan Poelaert, Susanna Price, Gregor Prosen, Shalim Rodriguez, Philippe Rola, Colin Royse, Yale Tung Chen, Mike Wells, Adrian Wong, Wang Xiaoting, Wang Zhen, Yaseen Arabi

Published in: Critical Care | Issue 1/2020

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Abstract

COVID-19 has caused great devastation in the past year. Multi-organ point-of-care ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound (FoCUS) as a clinical adjunct has played a significant role in triaging, diagnosis and medical management of COVID-19 patients. The expert panel from 27 countries and 6 continents with considerable experience of direct application of PoCUS on COVID-19 patients presents evidence-based consensus using GRADE methodology for the quality of evidence and an expedited, modified-Delphi process for the strength of expert consensus. The use of ultrasound is suggested in many clinical situations related to respiratory, cardiovascular and thromboembolic aspects of COVID-19, comparing well with other imaging modalities. The limitations due to insufficient data are highlighted as opportunities for future research.
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Literature
1.
2.
Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020.
3.
Mojoli F, Mongodi S, Orlando A, Arisi E, Pozzi M, Civardi L, Tavazzi G, Baldanti F, Bruno R, Iotti GA, et al. Our recommendations for acute management of COVID-19. Crit Care. 2020;24(1):207.PubMedPubMedCentralCrossRef
4.
Alhazzani W, Moller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A et al. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med 2020.
5.
6.
7.
Grasselli G, Pesenti A, Cecconi M. Critical care utilization for the COVID-19 outbreak in lombardy. Italy: Early Experience and Forecast During an Emergency Response. JAMA; 2020.
8.
Chen X, Tang Y, Mo Y, Li S, Lin D, Yang Z, Yang Z, Sun H, Qiu J, Liao Y et al. A diagnostic model for coronavirus disease 2019 (COVID-19) based on radiological semantic and clinical features: a multi-center study. Eur Radiol 2020.
9.
Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, Cereda D, Coluccello A, Foti G, Fumagalli R et al. Baseline characteristics and outcomes of 1591 patients infected With SARS-CoV-2 admitted to ICUs of the lombardy region, Italy. JAMA 2020.
10.
Li Y, Yao L, Li J, Chen L, Song Y, Cai Z, Yang C. Stability issues of RT-PCR testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19. J Med Virol 2020.
11.
Abrams ER, Rose G, Fields JM, Esener D. Point-of-Care Ultrasound in the Evaluation of COVID-19. J Emerg Med 2020.
12.
13.
Antunez-Montes OY, Buonsenso D. Routine use of Point-of-Care lung ultrasound during the COVID-19 pandemic. Med Intensiva 2020.
14.
Bhoi S, Sahu AK, Mathew R, Sinha TP. Point-of-care ultrasound in COVID-19 pandemic. Postgrad Med J 2020.
15.
Dong D, Tang Z, Wang S, Hui H, Gong L, Lu Y, Xue Z, Liao H, Chen F, Yang F et al. The role of imaging in the detection and management of COVID-19: a review. IEEE Rev Biomed Eng 2020, PP.
16.
Duggan N, Liteplo AS, Shokoohi A, Goldsmith AJ. Using lung point-of-care ultrasound in suspected COVID-19: case series and proposed triage algorithm. Clin Pract Cases Emerg Med 2020:289–294.
17.
Guarracino F, Vetrugno L, Forfori F, Corradi F, Orso D, Bertini P, Ortalda A, Federici N, Copetti R, Bove T. Lung, heart, vascular, and diaphragm ultrasound examination of COVID-19 patients: a comprehensive approach. J Cardiothorac Vasc Anesth 2020.
18.
Piliego C, Strumia A, Stone MB, Pascarella G. The ultrasound guided triage: a new tool for prehospital management of COVID-19 pandemic. Anesth Analg 2020.
19.
Erika P, Andrea V, Cillis MG, Ioannilli E, Iannicelli T, Andrea M. Triage decision-making at the time of COVID-19 infection: the Piacenza strategy. Intern Emerg Med. 2020;15(5):879–82.PubMedCrossRefPubMedCentral
20.
Smargiassi A, Soldati G, Borghetti A, Scoppettuolo G, Tamburrini E, Testa AC, Moro F, Natale L, Larici AR, Buonsenso D et al. Lung ultrasonography for early management of patients with respiratory symptoms during COVID-19 pandemic. J Ultrasound 2020.
21.
Tierney DM, Huelster JS, Overgaard JD, Plunkett MB, Boland LL, St Hill CA, Agboto VK, Smith CS, Mikel BF, Weise BE, et al. Comparative performance of pulmonary ultrasound, chest radiograph, and CT among patients with acute respiratory failure. Crit Care Med. 2020;48(2):151–7.PubMedCrossRef
22.
Volpicelli G, Elbarbary M, Blaivas M, Lichtenstein DA, Mathis G, Kirkpatrick AW, Melniker L, Gargani L, Noble VE, Via G, et al. International evidence-based recommendations for point-of-care lung ultrasound. Intensive Care Med. 2012;38(4):577–91.PubMedCrossRef
23.
Ye X, Xiao H, Chen B, Zhang S. Accuracy of lung ultrasonography versus chest radiography for the diagnosis of adult community-acquired pneumonia: review of the literature and meta-analysis. PLoS ONE. 2015;10(6):e0130066.PubMedPubMedCentralCrossRef
24.
Pare JR, Camelo I, Mayo KC, Leo MM, Dugas JN, Nelson KP, Baker WE, Shareef F, Mitchell PM, Schechter-Perkins EM. Point-of-care Lung Ultrasound Is More Sensitive than Chest Radiograph for Evaluation of COVID-19. West J Emerg Med. 2020;21(4):771–8.PubMedPubMedCentralCrossRef
25.
Pivetta E, Goffi A, Lupia E, Tizzani M, Porrino G, Ferreri E, Volpicelli G, Balzaretti P, Banderali A, Iacobucci A, et al. Lung ultrasound-implemented diagnosis of acute decompensated heart failure in the ED: A SIMEU multicenter study. Chest. 2015;148(1):202–10.PubMedCrossRef
26.
Laursen CB, Sloth E, Lassen AT, Christensen R, Lambrechtsen J, Madsen PH, Henriksen DP, Davidsen JR, Rasmussen F. Point-of-care ultrasonography in patients admitted with respiratory symptoms: a single-blind, randomised controlled trial. Lancet Respir Med. 2014;2(8):638–46.PubMedCrossRef
27.
Hankins A, Bang H, Walsh P. Point of care lung ultrasound is useful when screening for CoVid-19 in Emergency Department patients. medRxiv 2020.
28.
Tan G, Lian X, Zhu Z, Wang Z, Huang F, Zhang Y, Zhao Y, He S, Wang X, Shen H et al. Use of Lung Ultrasound to Differentiate Coronavirus Disease 2019 (COVID-19) Pneumonia From Community-Acquired Pneumonia. Ultrasound Med Biol 2020.
29.
Peng QY, Wang XT, Zhang LN, Chinese Critical Care Ultrasound Study G. Findings of lung ultrasonography of novel corona virus pneumonia during the 2019–2020 epidemic. Intensive Care Med 2020.
30.
Soldati G, Smargiassi A, Inchingolo R, Buonsenso D, Perrone T, Briganti DF, Perlini S, Torri E, Mariani A, Mossolani EE et al. Proposal for international standardization of the use of lung ultrasound for COVID-19 patients; a simple, quantitative, reproducible method. J Ultrasound Med 2020.
31.
32.
Soldati G, Smargiassi A, Inchingolo R, Buonsenso D, Perrone T, Briganti DF, Perlini S, Torri E, Mariani A, Mossolani EE et al. Is there a role for lung ultrasound during the COVID-19 pandemic? J Ultrasound Med 2020.
33.
Nouvenne A, Zani MD, Milanese G, Parise A, Baciarello M, Bignami EG, Odone A, Sverzellati N, Meschi T, Ticinesi A. Lung ultrasound in COVID-19 pneumonia: correlations with chest CT on hospital admission. Respiration 2020:1–8.
34.
Zieleskiewicz L, Markarian T, Lopez A, Taguet C, Mohammedi N, Boucekine M, Baumstarck K, Besch G, Mathon G, Duclos G et al. Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia. Intensive Care Med 2020.
35.
Bonadia NC, Piano A, Buonsenso D, Gilardi E, Kadhim C, Torelli E, Petrucci M, Di Maurizio L, Biasucci DG, Fuorlo M, Forte E, Zaccaria R, Franceschi F. Lung ultrasound findings are associated with mortality and need of intensive care admission in COVID-19 patients evaluated in the Emergency Department. Ultrasound Med Biol 2020.
36.
Lichter Y, Topilsky Y, Taieb P, Banai A, Hochstadt A, Merdler I, Gal Oz A, Vine J, Goren O, Cohen B et al. Lung ultrasound predicts clinical course and outcomes in COVID-19 patients. Intensive Care Med 2020.
37.
Bar S, Lecourtois A, Diouf M, Goldberg E, Bourbon C, Arnaud E, Domisse L, Dupont H, Gosset P. The association of lung ultrasound images with COVID-19 infection in an emergency room cohort. Anaesthesia 2020.
38.
Benchoufi MBJ, Chauvin A, Dion E, Baranne ML, Levan F, Vicaut E, Bourrier P. Lung injury in patients with or suspected COVID-19 : a comparison between lung ultrasound and chest CT-scanner severity assessments, an observational study. In: medRxiv preprint. 2020.
39.
Peyrony O, Marbeuf-Gueye C, Truong V, Giroud M, Riviere C, Khenissi K, Legay L, Simonetta M, Elezi A, Principe A et al. Accuracy of Emergency Department Clinical Findings for Diagnosis of Coronavirus Disease 2019. Ann Emerg Med 2020.
40.
Tung Chen YLFR, Rodriguez Fuertes P. The role of point-of care ultrasonography in the initial characterization of COVID-19 patients: Results from a prospective multicentric study. medRxiv 2020.
41.
Llamas-Alvarez AM, Tenza-Lozano EM, Latour-Perez J. Accuracy of lung ultrasonography in the diagnosis of pneumonia in adults: systematic review and meta-analysis. Chest. 2017;151(2):374–82.PubMedCrossRef
42.
Bataille B, Riu B, Ferre F, Moussot PE, Mari A, Brunel E, Ruiz J, Mora M, Fourcade O, Genestal M, et al. Integrated use of bedside lung ultrasound and echocardiography in acute respiratory failure: a prospective observational study in ICU. Chest. 2014;146(6):1586–93.PubMedCrossRef
43.
Kajimoto K, Madeen K, Nakayama T, Tsudo H, Kuroda T, Abe T. Rapid evaluation by lung-cardiac-inferior vena cava (LCI) integrated ultrasound for differentiating heart failure from pulmonary disease as the cause of acute dyspnea in the emergency setting. Cardiovasc Ultrasound. 2012;10(1):49.PubMedPubMedCentralCrossRef
44.
Nazerian P, Vanni S, Volpicelli G, Gigli C, Zanobetti M, Bartolucci M, Ciavattone A, Lamorte A, Veltri A, Fabbri A, et al. Accuracy of point-of-care multiorgan ultrasonography for the diagnosis of pulmonary embolism. Chest. 2014;145(5):950–7.PubMedCrossRef
45.
Zanobetti M, Scorpiniti M, Gigli C, Nazerian P, Vanni S, Innocenti F, Stefanone VT, Savinelli C, Coppa A, Bigiarini S, et al. Point-of-care ultrasonography for evaluation of acute dyspnea in the ED. Chest. 2017;151(6):1295–301.PubMedCrossRef
46.
Volpicelli G, Lamorte A, Tullio M, Cardinale L, Giraudo M, Stefanone V, Boero E, Nazerian P, Pozzi R, Frascisco MF. Point-of-care multiorgan ultrasonography for the evaluation of undifferentiated hypotension in the emergency department. Intensive Care Med. 2013;39(7):1290–8.PubMedCrossRef
47.
Via G, Hussain A, Wells M, Reardon R, ElBarbary M, Noble VE, Tsung JW, Neskovic AN, Price S, Oren-Grinberg A et al: International evidence-based recommendations for focused cardiac ultrasound. J Am Soc Echocardiogr 2014, 27(7):683 e681–683 e633.
48.
McInnes MDF, Leeflang MMG, Salameh JP, McGrath TA, van der Pol CB, Frank RA, Prager R, Hare SS. Dennie C. Imaging tests for the diagnosis of COVID-19 (Protocol). In: Cochrane Library. Wiley; 2020.
49.
Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system. Nat Rev Cardiol 2020.
50.
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD. Executive group on behalf of the joint european society of cardiology/American college of cardiology/American heart association/world heart federation task force for the universal definition of myocardial i: fourth universal definition of myocardial infarction (2018). Circulation. 2018;138(20):e618–51.CrossRefPubMed
51.
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020.
52.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan China. Lancet. 2020;395(10223):497–506.PubMedPubMedCentralCrossRef
53.
Shi S, Qin M, Shen B, Cai Y, Liu T, Yang F, Gong W, Liu X, Liang J, Zhao Q et al. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. JAMA Cardiol 2020
54.
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD, Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237–69.CrossRefPubMed
55.
Kociol RD, Cooper LT, Fang JC, Moslehi JJ, Pang PS, Sabe MA, Shah RV, Sims DB, Thiene G, Vardeny O, et al. Recognition and initial management of fulminant myocarditis: a scientific statement from the american heart association. Circulation. 2020;141(6):e69–92.PubMedCrossRef
56.
McCarthy CP, Raber I, Chapman AR, Sandoval Y, Apple FS, Mills NL, Januzzi JL, Jr. Myocardial injury in the era of high-sensitivity cardiac troponin assays: a practical approach for clinicians. JAMA Cardiol 2019.
57.
Churchill TW, Bertrand PB, Bernard S, Namasivayam M, Churchill J, Crousillat D, Davis EF, Hung J, Picard MH. Echocardiographic features of COVID-19 illness and association with cardiac biomarkers. J Am Soc Echocardiogr. 2020;33(8):1053–4.PubMedPubMedCentralCrossRef
58.
Dweck MR, Bularga A, Hahn RT, Bing R, Lee KK, Chapman AR, White A, Salvo GD, Sade LE, Pearce K et al. Global evaluation of echocardiography in patients with COVID-19. Eur Heart J Cardiovasc Imaging 2020.
59.
Fried JA, Ramasubbu K, Bhatt R, Topkara VK, Clerkin KJ, Horn E, Rabbani L, Brodie D, Jain SS, Kirtane A et al. The variety of cardiovascular presentations of COVID-19. Circulation 2020.
60.
Price LC, McAuley DF, Marino PS, Finney SJ, Griffiths MJ, Wort SJ. Pathophysiology of pulmonary hypertension in acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2012;302(9):L803-815.PubMedPubMedCentralCrossRef
61.
Repesse X, Charron C, Vieillard-Baron A. Acute cor pulmonale in ARDS: rationale for protecting the right ventricle. Chest. 2015;147(1):259–65.PubMedCrossRef
62.
Clerkin KJ, Fried JA, Raikhelkar J, Sayer G, Griffin JM, Masoumi A, Jain SS, Burkhoff D, Kumaraiah D, Rabbani L, et al. COVID-19 and cardiovascular disease. Circulation. 2020;141(20):1648–55.PubMedCrossRef
63.
Cecconi M, De Backer D, Antonelli M, Beale R, Bakker J, Hofer C, Jaeschke R, Mebazaa A, Pinsky MR, Teboul JL et al: Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. Intensive Care Med 2014, 40(12):1795–1815.
64.
Price S, Platz E, Cullen L, Tavazzi G, Christ M, Cowie MR, Maisel AS, Masip J, Miro O, McMurray JJ, et al. Expert consensus document: Echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nat Rev Cardiol. 2017;14(7):427–40.PubMedPubMedCentralCrossRef
65.
Jain SS LQ, Raikhelkar J, Fried J, Elias P, Poterucha TJ, DeFilippis EM, Rosenblum H, Wang EY, Redfors B, Clerkin K, Griffin JM, Wan EY, Abdalla M, Bello NA, Hahn RT, Shimbo D, Weiner SD, Kirtane AJ, Kodali SK, Burkhoff D, Rabbani LE, Schwartz A, Leon MB, Homma S, Di Tullio MR, Sayer G, Uriel N, Anstey DE. Indications for and findings on transthoracic echocardiography in COVID-19. J Am Soc Echocardigr 2020.
66.
Johry AGB, Kirkpatrick JN, Lanspa M, Mulvagh S, Thamman R. ASE Statement on point-of-care ultrasound (PoCUS) during the 2019 novel coronavirus pandemic. J Am Soc Echocardigr 2020, in press.
67.
Cosyns B, Lochy S, Luchian ML, Gimelli A, Pontone G, Allard SD, de Mey J, Rosseel P, Dweck M, Petersen SE, et al. The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients. Eur Heart J Cardiovasc Imaging. 2020;21(7):709–14.PubMedCrossRef
68.
Zeng J, Huang J, Pan L. How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People's Hospital. Intensive Care Med 2020.
69.
Vignon P, Begot E, Mari A, Silva S, Chimot L, Delour P, Vargas F, Filloux B, Vandroux D, Jabot J, et al. Hemodynamic assessment of patients with septic shock using transpulmonary thermodilution and critical care echocardiography: a comparative study. Chest. 2018;153(1):55–64.PubMedCrossRef
70.
van Diepen S, Katz JN, Albert NM, Henry TD, Jacobs AK, Kapur NK, Kilic A, Menon V, Ohman EM, Sweitzer NK, et al. Contemporary management of cardiogenic shock: a scientific statement from the american heart association. Circulation. 2017;136(16):e232–68.PubMed
71.
Skouri HN, Dec GW, Friedrich MG, Cooper LT. Noninvasive imaging in myocarditis. J Am Coll Cardiol. 2006;48(10):2085–93.PubMedCrossRef
72.
Szekely Y, Lichter Y, Taieb P, Banai A, Hochstadt A, Merdler I, Gal Oz A, Rothschild E, Baruch G, Peri Y, et al. Spectrum of cardiac manifestations in COVID-19: a systematic echocardiographic study. Circulation. 2020;142(4):342–53.PubMedPubMedCentralCrossRef
73.
Tavazzi GCL, Caneva L, Mongodi S, Mojoli F. Thrombotic events in SARS-Cov 2 patients: an urgent call for ultrasound screening. Intensive Care Med 2020.
74.
Ren B, Yan F, Deng Z, Zhang S, Xiao L, Wu M, Cai L. Extremely high incidence of lower extremity deep venous thrombosis in 48 patients with severe COVID-19 in Wuhan. Circulation. 2020;142(2):181–3.PubMedCrossRef
75.
Helms J, Tacquard J, Severac F, Lorant J, Ohana M, Delabranche X, AL. E, Sepsis) aftCTGCRiICaSTGfGEaRi: High risk of thrombosis in patients in severe SARS-CoV-2 infection: a multicenter prospective cohort study. Intensive Care Med 2020, in press.
76.
Klok FA, Kruip M, van der Meer NJM, Arbous MS, Gommers D, Kant KM, Kaptein FHJ, van Paassen J, Stals MAM, Huisman MV et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19. Thromb Res 2020.
77.
Frantzeskaki F, Armaganidis A, Orfanos SE. Immunothrombosis in acute respiratory distress syndrome: cross talks between inflammation and coagulation. Respiration. 2017;93(3):212–25.PubMedCrossRef
78.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, Xiang J, Wang Y, Song B, Gu X, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.PubMedPubMedCentralCrossRef
79.
Tang N, Bai H, Chen X, Gong J, Li D, Sun Z. Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy. J Thromb Haemost 2020.
80.
Thachil J TN, Gando S, Falanga A, Cattaneo M, Levi M, Clark C, Iba T. ISTH interim guidance on recognition and management of coagulopathy in COVID-19. Thromb Haemosth 2020, in press.
81.
Demelo-Rodriguez P, Cervilla-Munoz E, Ordieres-Ortega L, Parra-Virto A, Toledano-Macias M, Toledo-Samaniego N, Garcia-Garcia A, Garcia-Fernandez-Bravo I, Ji Z, de-Miguel-Diez J et al. Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels. Thromb Res 2020, 192:23–26.
82.
Trimaille A, Curtiaud A, Marchandot B, Matsushita K, Sato C, Leonard-Lorant I, Sattler L, Grunebaum L, Ohana M, Von Hunolstein JJ, et al. Venous thromboembolism in non-critically ill patients with COVID-19 infection. Thromb Res. 2020;193:166–9.PubMedPubMedCentralCrossRef
83.
Blaivas M. Ultrasound in the detection of venous thromboembolism. Crit Care Med. 2007;35(5 Suppl):S224-234.PubMedCrossRef
84.
Marietta M, Ageno W, Artoni A, De Candia E, Gresele P, Marchetti M, Marcucci R, Tripodi A. COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET). Blood Transfus 2020.
85.
Obi AT, Barnes GD, Wakefield TW, Brown Rvt S, Eliason JL, Arndt E, Henke PK. Practical diagnosis and treatment of suspected venous thromboembolism during COVID-19 Pandemic. J Vasc Surg Venous Lymphat Disord 2020.
86.
Moores LK, Tritschler T, Brosnahan S, Carrier M, Collen JF, Doerschug K, Holley AB, Jimenez D, Le Gal G, Rali P et al. Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019: CHEST Guideline and Expert Panel Report. Chest 2020.
87.
Arabi YM, Burns KEA, Alsolamy SJ, Alshahrani MS, Al-Hameed FM, Arshad Z, Almaani M, Hawa H, Mandourah Y, Almekhlafi GA, et al. Surveillance or no surveillance ultrasonography for deep vein thrombosis and outcomes of critically ill patients: a pre-planned sub-study of the PREVENT trial. Intensive Care Med. 2020;46(4):737–46.PubMedCrossRef
88.
Marini JJ, Dellinger RP, Brodie D. Integrating the evidence: confronting the COVID-19 elephant. Intensive Care Med 2020.
89.
Gattinoni LCD, Caironi P, Busana M, Romitti F, Brazzi L, Camporota L. COVID-19 pneumonia: different respiratory treatment for different phenotypes? Intensive Care Med 2020.
90.
Gattinoni L, Caironi P, Pelosi P, Goodman LR. What has computed tomography taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med. 2001;164(9):1701–11.PubMedCrossRef
91.
Wang Y, Dong C, Hu Y, Li C, Ren Q, Zhang X, Shi H, Zhou M. Temporal Changes of CT Findings in 90 Patients with COVID-19 Pneumonia: A Longitudinal Study. Radiology 2020:200843.
92.
Rouby JJ, Puybasset L, Nieszkowska A, Lu Q. Acute respiratory distress syndrome: lessons from computed tomography of the whole lung. Crit Care Med. 2003;31(4 Suppl):S285-295.PubMedCrossRef
93.
Elharrar X, Trigui Y, Dols AM, Touchon F, Martinez S, Prud'homme E, Papazian L: Use of Prone Positioning in Nonintubated Patients With COVID-19 and Hypoxemic Acute Respiratory Failure. JAMA 2020.
94.
Coppo A, Bellani G, Winterton D, Di Pierro M, Soria A, Faverio P, Cairo M, Mori S, Messinesi G, Contro E, et al. Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study. Lancet Respir Med. 2020;8(8):765–74.PubMedPubMedCentralCrossRef
95.
Chiumello D, Umbrello M, Sferrazza Papa GF, Angileri A, Gurgitano M, Formenti P, Coppola S, Froio S, Cammaroto A, Carrafiello G. Global and Regional Diagnostic Accuracy of Lung Ultrasound Compared to CT in Patients With Acute Respiratory Distress Syndrome. Crit Care Med. 2019;47(11):1599–606.PubMedCrossRef
96.
Denault AY, Delisle S, Canty D, Royse A, Royse C, Serra XC, Gebhard CE, Couture EJ, Girard M, Cavayas YA et al. A proposed lung ultrasound and phenotypic algorithm for the care of COVID-19 patients with acute respiratory failure. Can J Anaesth 2020.
97.
Chiumello D, Mongodi S, Algieri I, Vergani GL, Orlando A, Via G, Crimella F, Cressoni M, Mojoli F. Assessment of lung aeration and recruitment by CT scan and ultrasound in acute respiratory distress syndrome patients. Crit Care Med. 2018;46(11):1761–8.PubMedCrossRef
98.
Bouhemad B, Mongodi S, Via G, Rouquette I. Ultrasound for “lung monitoring” of ventilated patients. Anesthesiology. 2015;122(2):437–47.PubMedCrossRef
99.
Bouhemad B, Brisson H, Le-Guen M, Arbelot C, Lu Q, Rouby JJ. Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med. 2011;183(3):341–7.PubMedCrossRef
100.
Haddam M, Zieleskiewicz L, Perbet S, Baldovini A, Guervilly C, Arbelot C, Noel A, Vigne C, Hammad E, Antonini F, et al. Lung ultrasonography for assessment of oxygenation response to prone position ventilation in ARDS. Intensive Care Med. 2016;42(10):1546–56.PubMedCrossRef
101.
Zhao Z, Jiang L, Xi X, Jiang Q, Zhu B, Wang M, Xing J, Zhang D. Prognostic value of extravascular lung water assessed with lung ultrasound score by chest sonography in patients with acute respiratory distress syndrome. BMC Pulm Med. 2015;15:98.PubMedPubMedCentralCrossRef
102.
Bataille B, Rao G, Cocquet P, Mora M, Masson B, Ginot J, Silva S, Moussot PE. Accuracy of ultrasound B-lines score and E/Ea ratio to estimate extravascular lung water and its variations in patients with acute respiratory distress syndrome. J Clin Monit Comput. 2015;29(1):169–76.PubMedCrossRef
103.
Via G, Lichtenstein D, Mojoli F, Rodi G, Neri L, Storti E, Klersy C, Iotti G, Braschi A. Whole lung lavage: a unique model for ultrasound assessment of lung aeration changes. Intensive Care Med. 2010;36(6):999–1007.PubMedCrossRef
104.
Dargent A, Chatelain E, Kreitmann L, Quenot JP, Cour M, Argaud L. group C-Ls. Lung ultrasound score to monitor COVID-19 pneumonia progression in patients with ARDS. PLoS ONE. 2020;15(7):e0236312.PubMedPubMedCentralCrossRef
105.
Deng Q, Zhang Y, Wang H, Chen L, Yang Z, Peng Z, Liu Y, Feng C, Huang X, Jiang N et al. Semiquantitative lung ultrasound scores in the evaluation and follow-up of critically ill patients with COVID-19: a single-center study. Acad Radiol 2020.
106.
Moller-Sorensen H, Gjedsted J, Lind Jorgensen V, Lindskov Hansen K. COVID-19 Assessment with Bedside Lung Ultrasound in a Population of Intensive Care Patients Treated with Mechanical Ventilation and ECMO. Diagnostics (Basel) 2020, 10(7).
107.
Marik PE, Linde-Zwirble WT, Bittner EA, Sahatjian J, Hansell D. Fluid administration in severe sepsis and septic shock, patterns and outcomes: an analysis of a large national database. Intensive Care Med. 2017;43(5):625–32.PubMedCrossRef
108.
Michard FM, Martin GS, Fumeaux T, Lobo S, Gonzalez F, Pinho-Oliveira V, Constantin JM. Haemodynamic Monitoring and Management in COVID-19 Intensive Care Patients/ An International Survey. Anaesthesia Critical Care & Pain Medicine 2020.
109.
Via G, Tavazzi G, Price S. Ten situations where inferior vena cava ultrasound may fail to accurately predict fluid responsiveness: a physiologically based point of view. Intensive Care Med. 2016;42(7):1164–7.PubMedCrossRef
110.
111.
112.
113.
Nair S, Sauthoff H: Assessing extravascular lung water with ultrasound: a tool to individualize fluid management? J Intensive Care Med 2019:885066619855000.
114.
Caltabeloti F, Monsel A, Arbelot C, Brisson H, Lu Q, Gu WJ, Zhou GJ, Auler JO, Rouby JJ. Early fluid loading in acute respiratory distress syndrome with septic shock deteriorates lung aeration without impairing arterial oxygenation: a lung ultrasound observational study. Crit Care. 2014;18(3):R91.PubMedPubMedCentralCrossRef
115.
Trezzi M, Torzillo D, Ceriani E, Costantino G, Caruso S, Damavandi PT, Genderini A, Cicardi M, Montano N, Cogliati C. Lung ultrasonography for the assessment of rapid extravascular water variation: evidence from hemodialysis patients. Intern Emerg Med. 2013;8(5):409–15.PubMedCrossRef
116.
Reisinger N, Koratala A. Lung ultrasound: a valuable tool for the assessment of dialysis patients with COVID-19. Clin Exp Nephrol 2020.
117.
Vieira ALS, Pazeli Junior JM, Bastos MG. Role of point-of-care ultrasound during the COVID-19 pandemic: our recommendations in the management of dialytic patients. Ultrasound J. 2020;12(1):30.PubMedPubMedCentralCrossRef
118.
Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020.
119.
Xie J, Tong Z, Guan X, Du B, Qiu H, Slutsky AS. Critical care crisis and some recommendations during the COVID-19 epidemic in China. Intensive Care Med 2020.
120.
Bouadma L, Lescure FX, Lucet JC, Yazdanpanah Y, Timsit JF. Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists. Intensive Care Med 2020.
121.
Mongodi S, Pozzi M, Orlando A, Bouhemad B, Stella A, Tavazzi G, Via G, Iotti GA, Mojoli F. Lung ultrasound for daily monitoring of ARDS patients on extracorporeal membrane oxygenation: preliminary experience. Intensive Care Med. 2018;44(1):123–4.PubMedCrossRef
122.
Enghard P, Rademacher S, Nee J, Hasper D, Engert U, Jorres A, Kruse JM. Simplified lung ultrasound protocol shows excellent prediction of extravascular lung water in ventilated intensive care patients. Crit Care. 2015;19:36.PubMedPubMedCentralCrossRef
123.
Heldeweg MM, Haaksma ME, Smit JM, Kraemer CVE, Tuinman PR. Lung ultrasound and computed tomography to monitor COVID-19 pneumonia in critically ill patients/ a two-center prospective cohort study. In: RES SQUARE preprint. 2020.
124.
Palmese F, Caroli B, Graziani A, Zanframundo G, Del Toro R, Sagrini E, Cataleta P, Domenicali M. Daily Evaluation of COVID-19 Patients Primarily Based on Lung Ultrasound: In Times of Emergency, It's Time to Change Some Paradigms. Am J Trop Med Hyg 2020, 103(2):922–923.
125.
Shokoohi H, Duggan NM, Garcia-de-Casasola Sanchez G, Torres-Arrese M, Tung-Chen Y. Lung ultrasound monitoring in patients with COVID-19 on home isolation. Am J Emerg Med 2020.
126.
Tung-Chen Y. Lung ultrasound in the monitoring of COVID-19 infection. Clin Med (Lond). 2020;20(4):e62–5.CrossRef
127.
Mongodi S, Via G, Girard M, Rouquette I, Misset B, Braschi A, Mojoli F, Bouhemad B. Lung ultrasound for early diagnosis of ventilator-associated pneumonia. Chest. 2016;149(4):969–80.PubMedCrossRef
128.
Bouhemad B, Liu ZH, Arbelot C, Zhang M, Ferarri F, Le-Guen M, Girard M, Lu Q, Rouby JJ. Ultrasound assessment of antibiotic-induced pulmonary reaeration in ventilator-associated pneumonia. Crit Care Med. 2010;38(1):84–92.PubMedCrossRef
129.
Peris A, Tutino L, Zagli G, Batacchi S, Cianchi G, Spina R, Bonizzoli M, Migliaccio L, Perretta L, Bartolini M, et al. The use of point-of-care bedside lung ultrasound significantly reduces the number of radiographs and computed tomography scans in critically ill patients. Anesth Analg. 2010;111(3):687–92.PubMedCrossRef
130.
Mongodi S, Orlando A, Arisi E, Tavazzi G, Santangelo E, Caneva L, Pozzi M, Pariani E, Bettini G, Maggio G, et al. Lung ultrasound in patients with acute respiratory failure reduces conventional imaging and health care provider exposure to COVID-19. Ultrasound Med Biol. 2020;46(8):2090–3.PubMedPubMedCentralCrossRef
131.
Alrajab S, Youssef AM, Akkus NI, Caldito G. Pleural ultrasonography versus chest radiography for the diagnosis of pneumothorax: review of the literature and meta-analysis. Crit Care. 2013;17(5):R208.PubMedPubMedCentralCrossRef
132.
133.
Mongodi S, Bouhmad B, Orlando A, Stella A, Via G, Iotti G, Mojoli F. Lung ultrasound before and after fiberbronchoscopy - modifications may improve ventilator associated pneumonia diagnosis - in: Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 15–18 March 2016. Crit Care 2016, 20:347.
134.
Zagli G, Cozzolino M, Terreni A, Biagioli T, Caldini AL, Peris A. Diagnosis of ventilator-associated pneumonia: a pilot, exploratory analysis of a new score based on procalcitonin and chest echography. Chest. 2014;146(6):1578–85.PubMedCrossRef
135.
Dres M, Goligher EC, Heunks LMA, Brochard LJ. Critical illness-associated diaphragm weakness. Intensive Care Med. 2017;43(10):1441–52.PubMedCrossRef
136.
Soummer A, Perbet S, Brisson H, Arbelot C, Constantin JM, Lu Q, Rouby JJ. Lung Ultrasound Study G: Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress*. Crit Care Med. 2012;40(7):2064–72.PubMedCrossRef
137.
Bouhemad B, Mojoli F, Nowobilski N, Hussain A, Rouquette I, Guinot PG, Mongodi S. Use of combined cardiac and lung ultrasound to predict weaning failure in elderly, high-risk cardiac patients: a pilot study. Intensive Care Med. 2020;46(3):475–84.PubMedCrossRef
138.
Li C, Li X, Han H, Cui H, Wang G, Wang Z. Diaphragmatic ultrasonography for predicting ventilator weaning: A meta-analysis. Medicine (Baltimore). 2018;97(22):e10968.CrossRef
139.
Silva S, Ait Aissa D, Cocquet P, Hoarau L, Ruiz J, Ferre F, Rousset D, Mora M, Mari A, Fourcade O, et al. Combined Thoracic Ultrasound Assessment during a Successful Weaning Trial Predicts Postextubation Distress. Anesthesiology. 2017;127(4):666–74.PubMedCrossRef
140.
Dres M, Dube BP, Goligher E, Vorona S, Demiri S, Morawiec E, Mayaux J, Brochard L, Similowski T, Demoule A. Usefulness of Parasternal Intercostal Muscle Ultrasound during Weaning from Mechanical Ventilation. Anesthesiology 2020.
141.
Razazi K, Boissier F, Neuville M, Jochmans S, Tchir M, May F, de Prost N, Brun-Buisson C, Carteaux G, Mekontso Dessap A. Pleural effusion during weaning from mechanical ventilation: a prospective observational multicenter study. Ann Intensive Care. 2018;8(1):103.PubMedPubMedCentralCrossRef
142.
Mekontso Dessap A, Roche-Campo F, Kouatchet A, Tomicic V, Beduneau G, Sonneville R, Cabello B, Jaber S, Azoulay E, Castanares-Zapatero D, et al. Natriuretic peptide-driven fluid management during ventilator weaning: a randomized controlled trial. Am J Respir Crit Care Med. 2012;186(12):1256–63.PubMedCrossRef
143.
Gernoth C, Wagner G, Pelosi P, Luecke T. Respiratory and haemodynamic changes during decremental open lung positive end-expiratory pressure titration in patients with acute respiratory distress syndrome. Crit Care. 2009;13(2):R59.PubMedPubMedCentralCrossRef
144.
Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020.
145.
Pan XW, Xu D, Zhang H, Zhou W, Wang LH, Cui XG. Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis. Intensive Care Med 2020.
146.
Chougar L, Shor N, Weiss N, Galanaud D, Leclercq D, Mathon B, Belkacem S, Stroer S, Burrel S, Boutolleau D et al. Retrospective Observational Study of Brain Magnetic Resonance Imaging Findings in Patients with Acute SARS-CoV-2 Infection and Neurological Manifestations. Radiology 2020:202422.
147.
Barozzi L, Valentino M, Santoro A, Mancini E, Pavlica P. Renal ultrasonography in critically ill patients. Crit Care Med. 2007;35(5 Suppl):S198-205.PubMedCrossRef
148.
Beaubien-Souligny W RP, Haycock K, Bouchard J, Lamarche Y, Spiegel R, Denault AY. Quantifying systemic congestion with Point-Of-Care ultrasound: Development of the Venous Excess Ultrasound grading system. The Ultrasound Journal 2020, in press.
149.
Perez-Calatayud AA, Carrillo-Esper R, Anica-Malagon ED, Briones-Garduno JC, Arch-Tirado E, Wise R, Malbrain M. Point-of-care gastrointestinal and urinary tract sonography in daily evaluation of gastrointestinal dysfunction in critically ill patients (GUTS Protocol). Anaesthesiol Intensive Ther. 2018;50(1):40–8.PubMedCrossRef
150.
Hoffmann B, Nurnberg D, Westergaard MC. Focus on abnormal air: diagnostic ultrasonography for the acute abdomen. Eur J Emerg Med. 2012;19(5):284–91.PubMedCrossRef
151.
Bhayana R, Som A, Li MD, Carey DE, Anderson MA, Blake MA, Catalano O, Gee MS, Hahn PF, Harisinghani M et al: Abdominal Imaging Findings in COVID-19: Preliminary Observations. Radiology 2020:201908.
152.
Robba C, Goffi A, Geeraerts T, Cardim D, Via G, Czosnyka M, Park S, Sarwal A, Padayachy L, Rasulo F, et al. Brain ultrasonography: methodology, basic and advanced principles and clinical applications A narrative review. Intensive Care Med. 2019;45(7):913–27.PubMedCrossRef
153.
McMahon SR, De Francis G, Schwartz S, Duvall WL, Arora B, Silverman DI. Tablet-based limited echocardiography to reduce sonographer scan and decontamination time during the COVID-19 Pandemic. J Am Soc Echocardiogr. 2020;33(7):895–9.PubMedPubMedCentralCrossRef
154.
Bobbia X, Chabannon M, Chevallier T, de La Coussaye JE, Lefrant JY, Pujol S, Claret PG, Zieleskiewicz L, Roger C, Muller L. Assessment of five different probes for lung ultrasound in critically ill patients: A pilot study. Am J Emerg Med. 2018;36(7):1265–9.PubMedCrossRef
155.
Ye R, Zhou X, Shao F, Xiong L, Hong J, Huang H, Tong W, Wang J, Chen S, Cui A et al. Feasibility of a 5G-based robot-assisted remote ultrasound system for cardiopulmonary assessment of COVID-19 patients. Chest 2020.
156.
Levine AR, McCurdy MT, Zubrow MT, Papali A, Mallemat HA, Verceles AC. Tele-intensivists can instruct non-physicians to acquire high-quality ultrasound images. J Crit Care. 2015;30(5):871–5.PubMedCrossRef
157.
Britton N, Miller MA, Safadi S, Siegel A, Levine AR, McCurdy MT. Tele-ultrasound in resource-limited settings: a systematic review. Front Public Health. 2019;7:244.PubMedPubMedCentralCrossRef
158.
Ma IW, Somayaji R, Rennert-May E, Minardi J, Walsh MH, Wiskar K, Smyth LM, Burgoyne S, Chan B, Haroon BA, Desy J. Canadian Internal Medicine Ultrasound (CIMUS) Recommendations Regarding Internal Medicine Point- of-Care Ultrasound (PoCUS) use during Coronavirus (COVID-19) pandemic. Canadian Journal of General Internal Medicine. 2020;15(2):8–11.CrossRef
159.
160.
van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med 2020.
Metadata
Title
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus
Authors
Arif Hussain
Gabriele Via
Lawrence Melniker
Alberto Goffi
Guido Tavazzi
Luca Neri
Tomas Villen
Richard Hoppmann
Francesco Mojoli
Vicki Noble
Laurent Zieleskiewicz
Pablo Blanco
Irene W. Y. Ma
Mahathar Abd. Wahab
Abdulmohsen Alsaawi
Majid Al Salamah
Martin Balik
Diego Barca
Karim Bendjelid
Belaid Bouhemad
Pablo Bravo-Figueroa
Raoul Breitkreutz
Juan Calderon
Jim Connolly
Roberto Copetti
Francesco Corradi
Anthony J. Dean
André Denault
Deepak Govil
Carmela Graci
Young-Rock Ha
Laura Hurtado
Toru Kameda
Michael Lanspa
Christian B. Laursen
Francis Lee
Rachel Liu
Massimiliano Meineri
Miguel Montorfano
Peiman Nazerian
Bret P. Nelson
Aleksandar N. Neskovic
Ramon Nogue
Adi Osman
José Pazeli
Elmo Pereira-Junior
Tomislav Petrovic
Emanuele Pivetta
Jan Poelaert
Susanna Price
Gregor Prosen
Shalim Rodriguez
Philippe Rola
Colin Royse
Yale Tung Chen
Mike Wells
Adrian Wong
Wang Xiaoting
Wang Zhen
Yaseen Arabi
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03369-5

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