Skip to main content
Top
Published in: Critical Care 1/2020

01-12-2020 | Nutrition | Research Letter

Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19

Authors: John Whittle, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, for the LEEP-COVID Study Group

Published in: Critical Care | Issue 1/2020

Login to get access

Excerpt

COVID-19 infection results in respiratory failure requiring ICU care in a small, yet significant, number of patients [1]. The longitudinal metabolic phenotype and energy expenditure of this novel pandemic disease has yet to be described. As a marked and often prolonged, systemic inflammatory response (SIRS) has been suggested to be a hallmark of severe COVID-19 infection [1], we hypothesized a prolonged hypermetabolic state would evolve over ICU stay that would persist beyond the 7–10 day hypermetabolic phase described previously in other ICU conditions [2]. …
Literature
2.
go back to reference Uehara M, Plank LD, Hill GL. Components of energy expenditure in patients with severe sepsis and major trauma: a basis for clinical care. Crit Care Med. 1999;27(7):1295–302.CrossRef Uehara M, Plank LD, Hill GL. Components of energy expenditure in patients with severe sepsis and major trauma: a basis for clinical care. Crit Care Med. 1999;27(7):1295–302.CrossRef
3.
go back to reference Singer P, Blaser AR, Berger MM, Alhazzani W, Calder PC, Casaer MP, Hiesmayr M, Mayer K, Montejo JC, Pichard C, et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019;38(1):48–79.CrossRef Singer P, Blaser AR, Berger MM, Alhazzani W, Calder PC, Casaer MP, Hiesmayr M, Mayer K, Montejo JC, Pichard C, et al. ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019;38(1):48–79.CrossRef
4.
go back to reference McClave SA, Taylor BE, Martindale RG, Warren MM, Johnson DR, Braunschweig C, McCarthy MS, Davanos E, Rice TW, Cresci GA, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2016;40(2):159–211.CrossRef McClave SA, Taylor BE, Martindale RG, Warren MM, Johnson DR, Braunschweig C, McCarthy MS, Davanos E, Rice TW, Cresci GA, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2016;40(2):159–211.CrossRef
5.
go back to reference Oshima T, Delsoglio M, Dupertuis YM, Singer P, De Waele E, Veraar C, Heidegger CP, Wernermann J, Wischmeyer PE, Berger MM et al: The clinical evaluation of the new indirect calorimeter developed by the ICALIC project. Clin Nutr. 2020:S0261-5614(20)30040-6. Doi: https://doi.org/10.1016/j.clnu.2020.01.017. Online ahead of print. Oshima T, Delsoglio M, Dupertuis YM, Singer P, De Waele E, Veraar C, Heidegger CP, Wernermann J, Wischmeyer PE, Berger MM et al: The clinical evaluation of the new indirect calorimeter developed by the ICALIC project. Clin Nutr. 2020:S0261-5614(20)30040-6. Doi: https://​doi.​org/​10.​1016/​j.​clnu.​2020.​01.​017. Online ahead of print.
6.
go back to reference Koekkoek WAC, Menger YA, van Zanten FJL, van Dijk D, van Zanten ARH. The effect of cisatracurium infusion on the energy expenditure of critically ill patients: an observational cohort study. Crit Care. 2020;24(1):32.CrossRef Koekkoek WAC, Menger YA, van Zanten FJL, van Dijk D, van Zanten ARH. The effect of cisatracurium infusion on the energy expenditure of critically ill patients: an observational cohort study. Crit Care. 2020;24(1):32.CrossRef
Metadata
Title
Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19
Authors
John Whittle
Jeroen Molinger
David MacLeod
Krista Haines
Paul E. Wischmeyer
for the LEEP-COVID Study Group
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03286-7

Other articles of this Issue 1/2020

Critical Care 1/2020 Go to the issue