Published in:
01-12-2020 | Nutrition | Research Letter
Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19
Authors:
John Whittle, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, for the LEEP-COVID Study Group
Published in:
Critical Care
|
Issue 1/2020
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Excerpt
COVID-19 infection results in respiratory failure requiring ICU care in a small, yet significant, number of patients [
1]. The longitudinal metabolic phenotype and energy expenditure of this novel pandemic disease has yet to be described. As a marked and often prolonged, systemic inflammatory response (SIRS) has been suggested to be a hallmark of severe COVID-19 infection [
1], we hypothesized a prolonged hypermetabolic state would evolve over ICU stay that would persist beyond the 7–10 day hypermetabolic phase described previously in other ICU conditions [
2]. …