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Critical Care
Published in: Critical Care 1/2020

Open Access 01-12-2020 | Acute Respiratory Distress-Syndrome | Letter

Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19

Authors: Alexander Supady, Daniel Duerschmied, Christoph Bode, Marina Rieder, Achim Lother

Published in: Critical Care | Issue 1/2020

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Excerpt

With great interest we read the article by Convertino et al. discussing potential treatment targets for pharmacological immunomodulation in coronavirus disease 2019 (COVID-19) with acute respiratory distress syndrome (ARDS) [1]. We would like to add to the debate some thoughts about cytokine adsorption, which was mentioned only in passing in this discussion. …
Literature
1.
Convertino I, Tuccori M, Ferraro S, Valdiserra G, Cappello E, Focosi D, Blandizzi C. Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients. Crit Care. 2020;24(1):331.CrossRef
2.
Rieder M, Wengenmayer T, Staudacher D, Duerschmied D, Supady A. Cytokine adsorption in patients with severe COVID-19 pneumonia requiring extracorporeal membrane oxygenation. Crit Care. 2020;24(1):435.CrossRef
3.
4.
Hadjadj J, Yatim N, Barnabei L, Corneau A, Boussier J, Smith N, Pere H, Charbit B, Bondet V, Chenevier-Gobeaux C, et al. Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients. Science. 2020;369(6504):718–24.
5.
Poli EC, Alberio L, Bauer-Doerries A, Marcucci C, Roumy A, Kirsch M, De Stefano E, Liaudet L, Schneider AG. Cytokine clearance with CytoSorb(R) during cardiac surgery: a pilot randomized controlled trial. Crit Care. 2019;23(1):108.CrossRef
Metadata
Title
Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19
Authors
Alexander Supady
Daniel Duerschmied
Christoph Bode
Marina Rieder
Achim Lother
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-03238-1

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