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Published in: Critical Care 1/2020

01-12-2020 | Stroke | Letter

Mechanical ventilation in patients with acute ischemic stroke: from pathophysiology to clinical practice

Authors: Jiguo Gao, Chunkui Zhou, Hongliang Zhang

Published in: Critical Care | Issue 1/2020

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Excerpt

Robba and colleagues are to be commended for exploring the pathophysiology of brain-lung interactions after acute ischemic stroke and the management of mechanical ventilation in these patients via a narrative review [1]. Pulmonary complications are common in patients with acute ischemic stroke and are associated with a high risk of mortality. The mechanism of lung damage after brain injury is described as a “double-hit model,” which appears adequate to explain some pathophysiological phenomena in the lung secondary to stroke [1]. However, pulmonary complications after acute ischemic stroke may occur with more complex mechanism. …
Literature
1.
go back to reference Robba C, Bonatti G, Battaglini D, Rocco PRM, Pelosi P. Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice. Crit Care. 2019;23:388.CrossRef Robba C, Bonatti G, Battaglini D, Rocco PRM, Pelosi P. Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice. Crit Care. 2019;23:388.CrossRef
2.
go back to reference Emsley HC, Hopkins SJ. Acute ischaemic stroke and infection: recent and emerging concepts. Lancet Neurol. 2008;7:341–53.CrossRef Emsley HC, Hopkins SJ. Acute ischaemic stroke and infection: recent and emerging concepts. Lancet Neurol. 2008;7:341–53.CrossRef
3.
go back to reference Hoffmann S, Harms H, Ulm L, Nabavi DG, Mackert BM, Schmehl I, et al. Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia – The PREDICT study. J Cereb Blood Flow Metab. 2017;37:3671–82.CrossRef Hoffmann S, Harms H, Ulm L, Nabavi DG, Mackert BM, Schmehl I, et al. Stroke-induced immunodepression and dysphagia independently predict stroke-associated pneumonia – The PREDICT study. J Cereb Blood Flow Metab. 2017;37:3671–82.CrossRef
4.
go back to reference Liu Q, Jin WN, Liu Y, Shi K, Sun H, Zhang F, et al. Brain ischemia suppresses immunity in the periphery and brain via different neurogenic innervations. Immunity. 2017;46:474–87.CrossRef Liu Q, Jin WN, Liu Y, Shi K, Sun H, Zhang F, et al. Brain ischemia suppresses immunity in the periphery and brain via different neurogenic innervations. Immunity. 2017;46:474–87.CrossRef
5.
go back to reference Austin V, Ku JM, Miller AA, Vlahos R. Ischaemic stroke in mice induces lung inflammation but not acute lung injury. Sci Rep. 2019;9:3622.CrossRef Austin V, Ku JM, Miller AA, Vlahos R. Ischaemic stroke in mice induces lung inflammation but not acute lung injury. Sci Rep. 2019;9:3622.CrossRef
6.
go back to reference Samary CS, Ramos AB, Maia LA, Rocha NN, Santos CL, Magalhães RF, et al. Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats. Crit Care. 2018;22:249.CrossRef Samary CS, Ramos AB, Maia LA, Rocha NN, Santos CL, Magalhães RF, et al. Focal ischemic stroke leads to lung injury and reduces alveolar macrophage phagocytic capability in rats. Crit Care. 2018;22:249.CrossRef
7.
go back to reference Samary CS, Pelosi P, Leme Silva P, Rocco PRM. Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy. Crit Care. 2016;20:391.CrossRef Samary CS, Pelosi P, Leme Silva P, Rocco PRM. Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy. Crit Care. 2016;20:391.CrossRef
8.
go back to reference Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke. 2012;43:3063–70.CrossRef Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, et al. Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke. 2012;43:3063–70.CrossRef
Metadata
Title
Mechanical ventilation in patients with acute ischemic stroke: from pathophysiology to clinical practice
Authors
Jiguo Gao
Chunkui Zhou
Hongliang Zhang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-2806-x

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