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Critical Care
Published in: Critical Care 1/2020

01-12-2020 | Acute Kidney Injury | Research Letter

The value of plasma pro-enkephalin and adrenomedullin for the prediction of sepsis-associated acute kidney injury in critically ill patients

Authors: Ruijin Liu, Xiaoya Zheng, Hongliang Wang, Sicong Wang, Kaijiang Yu, Changsong Wang

Published in: Critical Care | Issue 1/2020

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Excerpt

Kidney function is commonly affected by sepsis, which is one of the most prominent causes of acute kidney injury (AKI) [1]. Seeking early, reliable biomarkers for the detection of AKI in critically ill patients with sepsis, it is of great importance to conduct successful interventions and reduce adverse outcomes. …
Literature
1.
Murugan R, Karajala-Subramanyam V, Lee M, Yende S, Kong L, Carter M, et al. Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int. 2010;77(6):527–35.CrossRef
2.
Arbit B, Marston N, Shah K, Lee EL, Aramin H, Clopton P, et al. Prognostic usefulness of proenkephalin in stable ambulatory patients with heart failure. Am J Cardiol. 2016;117(8):1310–4.CrossRef
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Bernal-Morell E, García-Villalba E, Vera MDC, Medina B, Martinez M, Callejo V, et al. Usefulness of midregional pro-adrenomedullin as a marker of organ damage and predictor of mortality in patients with sepsis. J Inf Secur. 2018;76(3):249–57.
4.
Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10.CrossRef
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Kellum JA, Lameire N, KDIGO AKI Guideline Work Group. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care. 2013;17(1):204.CrossRef
Metadata
Title
The value of plasma pro-enkephalin and adrenomedullin for the prediction of sepsis-associated acute kidney injury in critically ill patients
Authors
Ruijin Liu
Xiaoya Zheng
Hongliang Wang
Sicong Wang
Kaijiang Yu
Changsong Wang
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-02887-6

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