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Critical Care
Published in: Critical Care 1/2019

Open Access 01-12-2019 | Letter

Inducible metabolic pathway for citrate metabolism in case of major liver dysfunction: fact or fiction?

Authors: Patrick M. Honore, David De Bels, Sebastien Redant, Rachid Attou, Luc Kugener, Willem Boer

Published in: Critical Care | Issue 1/2019

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Excerpt

With interest, we read the paper published by Klingele et al. [1] in a recent issue of critical care. …
Literature
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Klingele M, Stadler T, Fliser D, Speer T, Groesdonk HV, Raddatz A. Long-term continuous renal replacement therapy and anticoagulation with citrate in critically ill patients with severe liver dysfunction. Crit Care. 2017;21:294.CrossRef
2.
Holmes RD, Moore KH, Ofenstein JP, Tsatsos P, Kiechle FL. Lactic acidosis and mitochondrial dysfunction in two children with peroxisomal disorders. J Inherit Metab Dis. 1993;16(2):368–80.CrossRef
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Kusaka M, Ui M. Activation of the Cori cycle by epinephrine. Am J Phys. 1977;232:E145–55.
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Schneider AG, Journois D, Rimmelé T. Complications of regional citrate anticoagulation: accumulation or overload? Crit Care. 2017;21:281.CrossRef
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Slowinski T, Morgera S, Joannidis M, Henneberg T, Stocker R, Helset E, et al. Safety and efficacy of regional citrate anticoagulation in continuous veno-venous hemodialysis in the presence of liver failure: the liver citrate anticoagulation threshold (L-CAT) observational study. Crit Care. 2015;19:349.CrossRef
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Zhang W, Bai M, Yu Y, Li L, Zhao L, Sun S, Chen X. Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis. Crit Care. 2019;23(1):22.CrossRef
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Khadzhynov D, Dahlinger A, Schelter C, Peters H, Kindgen-Milles D, Budde K, Lehner LJ, Halleck F, Staeck O, Slowinski T. Hyperlactatemia, lactate kinetics and prediction of citrate accumulation in critically ill patients undergoing continuous renal replacement therapy with regional citrate anticoagulation. Crit Care Med. 2017;45(9):e941–6.CrossRef
Metadata
Title
Inducible metabolic pathway for citrate metabolism in case of major liver dysfunction: fact or fiction?
Authors
Patrick M. Honore
David De Bels
Sebastien Redant
Rachid Attou
Luc Kugener
Willem Boer
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2019
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-019-2432-7

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