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Critical Care
Published in: Critical Care 1/2019

Open Access 01-12-2019 | Hypotension | Letter

Weaning order of vasoactive drugs

Authors: Vilto Michels Jr, Daisson José Trevisol

Published in: Critical Care | Issue 1/2019

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Excerpt

In the interesting paper by Jeon et al. [1] the incidence of hypotension while tapering vasopressors in patients recovering from septic shock on concomitant norepinephrine (NE) and vasopressin (AVP) was evaluated. Differing from other studies [2], the authors concluded that the incidence of hypotension was not related to the discontinuation order of the vasopressors, but was related to NE discontinuation. The authors suggested that AVP should be tapered before NE rather than the reverse. …
Literature
1.
Jeon K, Song JU, Chung CR, Yang JH, Suh GY. Incidence of hypotension according to the discontinuation order of vasopressors in the management of septic shock: a prospective randomized trial (DOVSS). Crit Care. 2018;22:131–42.CrossRef
2.
Musallam N, Altshuler D, Merchan C, Zakhary B, Aberle C, Papadopoulos J. Evaluating vasopressor discontinuation strategies in patients with septic shock on concomitant norepinephrine and vasopressin infusions. Ann Pharmacother. 2018;52(8):733–9.CrossRef
3.
Arellano DL, Hanneman SK. Vasopressor weaning in patients with septic shock. Crit Care Nurs Clin North Am. 2014;26(3):413–25.CrossRef
4.
Pang CCY, Tabrizchi R. The effects of noradrenaline, B-HT 920, methoxamine, angiotensin II and vasopressin on mean circulatory filling pressure in conscious rats. Br J Pharmac. 1986;89(2):389–94.CrossRef
Metadata
Title
Weaning order of vasoactive drugs
Authors
Vilto Michels Jr
Daisson José Trevisol
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2019
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-018-2218-3

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