Published in:
Open Access
01-12-2017 | Letter
The forgotten value of the clinical examination to individualize and guide fluid resuscitation in patients with sepsis
Authors:
Gentle Sunder Shrestha, Martin Dünser, Mervyn Mer
Published in:
Critical Care
|
Issue 1/2017
Login to get access
Excerpt
Andrews et al. reported that protocol-driven fluid resuscitation was associated with enhanced lactate clearance but offset by more respiratory distress and substantially higher mortality in patients with sepsis in the sub-Saharan African setting with limited access to mechanical ventilators [
1]. Lack of access to oxygen and ventilation facilities is a frequent and widespread challenge in hospitals in low- and middle-income countries (LMICs), where approximately three-quarters of the world’s population reside. This needs to be considered while using contemporary international guidelines on the management of sepsis, which are largely based on scientific evidence originating from high-income settings [
2,
3]. …
