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Open Access 01-12-2018 | Letter

Use of a meta-analysis to assess the preventive effect of dexmedetomidine on cardiac surgery-associated acute kidney injury

Authors: Gui-Zhen Yang, Fu-Shan Xue, Ya-Yang Liu

Published in: Critical Care | Issue 1/2018

Excerpt

Shi and Tie [1] concluded in their meta-analysis that dexmedetomidine might be a promising prevention strategy for cardiac surgery-associated acute kidney injury (CSA-AKI). In a meta-analysis, the results from many studies are synthesized mathematically by complex statistical methods to assess the diversity among results and to estimate a common pooled effect with increased precision. Thus, the results of a meta-analysis are only as good as the quality of the collected data. We noted that some defects of the studies included in this meta-analysis would have made interpretation of their conclusions questionable. …

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Title: Use of a meta-analysis to assess the preventive effect of dexmedetomidine on cardiac surgery-associated acute kidney injury
Authors: Gui-Zhen Yang
Fu-Shan Xue
Ya-Yang Liu
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Critical Care / Issue 1/2018
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/s13054-017-1853-4

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Use of a meta-analysis to assess the preventive effect of dexmedetomidine on cardiac surgery-associated acute kidney injury

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