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Critical Care
Published in: Critical Care 1/2017

Open Access 01-12-2017 | Letter

Hydrolysed protein enteral nutrition is not superior to polymeric whole protein feeding with regard to gastrointestinal feeding tolerance and feeding adequacy

Authors: Arthur R. H. van Zanten, Gunnar Elke

Published in: Critical Care | Issue 1/2017

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Excerpt

We would like to comment on the SPIRIT trial by Jakob and co-workers comparing the effects of hydrolysed protein enteral nutrition (EN; Peptamen AF®) and isocaloric control polymeric whole protein feed (Isosource® Energy) on gastrointestinal feeding tolerance, including diarrhoea and feeding adequacy [1]. No differences in diarrhoea-free days and number of diarrhoea events were observed. …
Literature
1.
Jakob SM, Bütikofer L, Berger D, Coslovsky M, Takala J. A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient-the SPIRIT trial. Crit Care. 2017;21:140.CrossRefPubMedPubMedCentral
2.
3.
Reintam Blaser A, Malbrain ML, Starkopf J, et al. Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems. Intensive Care Med. 2012;38:384–94.CrossRefPubMedPubMedCentral
4.
McClave SA, Taylor BE, Martindale RG, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). J Parenter Enteral Nutr. 2016;40:159–211.CrossRef
Metadata
Title
Hydrolysed protein enteral nutrition is not superior to polymeric whole protein feeding with regard to gastrointestinal feeding tolerance and feeding adequacy
Authors
Arthur R. H. van Zanten
Gunnar Elke
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2017
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-017-1817-8

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