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Critical Care
Published in: Critical Care 1/2016

Open Access 01-12-2016 | Letter

Real-life use of vasopressors and inotropes in cardiogenic shock—observation is necessarily ‘theory-laden’

Published in: Critical Care | Issue 1/2016

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Excerpt

We commend the attempt of Tarvasmäki et al. [1] to identify the mortality risk associated with individual vaso-active agents used in cardiogenic shock. However, despite their rigorous statistical analysis, we recommend caution in interpreting these results. Propensity score matching accounts for prior bias in the choice of vaso-active agents, but this choice of agent is often deeply engrained in individual clinician dogma which even propensity score matching may not uncover. …
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Literature
1.
Tarvasmäki T, Lassus J, Varpula M, Sionis A, Sund R, Køber L, Spinar J, Parissis J, Banaszewski M, Silva Cardoso J, Carubelli V, Di Somma S, Mebazaa A, Harjola VP, CardShock study investigators. Current real-life use of vasopressors and inotropes in cardiogenic shock—adrenaline use is associated with excess organ injury and mortality. Crit Care. 2016;20(1):208.CrossRefPubMedPubMedCentral
2.
Ventura AM, Shieh HH, Bousso A, Góes PF, de Cássia FO, Fernandes I, de Souza DC, Paulo RL, Chagas F, Gilio AE. Double-blind prospective randomized controlled trial of dopamine versus epinephrine as first-line vasoactive drugs in pediatric septic shock. Crit Care Med. 2015;43(11):2292–302.CrossRefPubMed
3.
Metadata
Title
Real-life use of vasopressors and inotropes in cardiogenic shock—observation is necessarily ‘theory-laden’
Publication date
01-12-2016
Published in
Critical Care / Issue 1/2016
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-016-1473-4

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