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Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 1/2020

01-12-2020 | Gestational Diabetes | Research

Association between parity and macrosomia in Shaanxi Province of Northwest China

Authors: Fangliang Lei, Lili Zhang, Yuan Shen, Yaling Zhao, Yijun Kang, Pengfei Qu, Baibing Mi, Shaonong Dang, Hong Yan

Published in: Italian Journal of Pediatrics | Issue 1/2020

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Abstract

Objective

To explore the relationship between parity and macrosomia and provide the necessary reference for the maternal and children health service.

Method

A cross-sectional epidemiological survey with the purpose to assess the birth outcomes was conducted in Shaanxi province, China.

Results

The incidence of macrosomia in multiparas was higher than that in primiparas. Univariate analysis showed that maternal age < 25 years, peasant/housework, living in rural areas and female infants were the protective factors of macrosomia. The possibility of having a macrosomic infant also increased with gestational age, maternal education level, household wealth index, living in Central Shaanxi and gestational diabetes. The generalized linear mixed models represented the association between parity and macrosomia. After adjusting for statistically significant factors in univariate analysis from model 1 to model 3, the risk of being born macrosomia was 1.26 times higher for a multipara compared to that for a primipara.

Conclusions

Present study indicated parity of two children was associated with increased risk for macrosomic births compared with parity of one child. Compared to primiparas, multiparas should far strengthen the pre-pregnancy education and the guidance during pregnancy to control pre-pregnancy body mass index and pregnancy weight, and keep the appropriate exercise and balanced diet.
Literature
1.
Gage TB, Fang F, O'Neill E, Dirienzo G. Maternal education, birth weight, and infant mortality in the United States. Demography. 2013;50(2):615–35.CrossRef
2.
Lu Y, Zhang J, Lu X, Xi W, Li Z. Secular trends of macrosomia in Southeast China, 1994-2005. BMC Public Health. 2011;11:818.CrossRef
3.
Koyanagi A, Zhang J, Dagvadorj A, Hirayama F, Shibuya K, Souza JP, et al. Macrosomia in 23 developing countries: an analysis of a multicountry, facility-based, cross-sectional survey. Lancet. 2013;381(9865):476–83.CrossRef
4.
Ye J, Torloni MR, Ota E, Jayaratne K, Pileggi-Castro C, Ortiz-Panozo E, et al. Searching for the definition of macrosomia through an outcome-based approach in low- and middle-income countries: a secondary analysis of the WHO global survey in Africa, Asia and Latin America. BMC Pregnancy Childbirth. 2015;15:324.CrossRef
5.
Center for Health Statistics and Information, MOH, China (2004) An analysis report of National Health Services Survey in China, 2003 (in Chinese). Centre for Health Statistics and Information of Ministry of Health of People’s Republic of China, Beijing, China.
6.
Asplund CA, Seehusen DA, Callahan TL, Olsen C. Percentage change in antenatal body mass index as a predictor of neonatal macrosomia. Ann Fam Med. 2008;6(6):550–4.CrossRef
7.
Boulet SL, Alexander GR, Salihu HM, Pass M. Macrosomic births in the United States: determinants, outcomes, and proposed grades of risk. Am J Obstet Gynecol. 2003;188(5):1372–8.CrossRef
8.
Chatfield J. ACOG issues guidelines on fetal macrosomia. American College of Obstetricians and Gynecologists. Am Fam Physician. 2001;64(1):169–70.PubMed
9.
Hermann GM, Dallas LM, Haskell SE, Roghair RD. Neonatal macrosomia is an independent risk factor for adult metabolic syndrome. Neonatology. 2010;98(3):238–44.CrossRef
10.
Boney CM, Verma A, Tucker R, Vohr BR. Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus. Pediatrics. 2005;115(3):e290–6.CrossRef
11.
Oken E, Gillman MW. Fetal origins of obesity. Obes Res. 2003;11(4):496–506.CrossRef
12.
Lawn JE, Mwansa-Kambafwile J, Horta BL, Barros FC, Cousens S. ‘Kangaroo mother care’ to prevent neonatal deaths due to preterm birth complications. Int J Epidemiol. 2010;39(Suppl 1):i144–54.CrossRef
13.
Halileh S, Abu-Rmeileh N, Watt G, Spencer N, Gordon N. Determinants of birthweight: gender based analysis. Matern Child Health J. 2008;12(5):606–12.CrossRef
14.
Mohammad K, Kassab M, Gamble J, Creedy DK, Foster J. Factors associated with birth weight inequalities in Jordan. Int Nurs Rev. 2014;61(3):435–40.CrossRef
15.
Shah PS. Parity and low birth weight and preterm birth: a systematic review and meta-analyses. Acta Obstet Gynecol Scand. 2010;89(7):862–75.CrossRef
16.
Beaty TH, Skjaerven R, Breazeale DR, Liang KY. Analyzing sibship correlations in birth weight using large sibships from Norway. Genet Epidemiol. 1997;14(4):423–33.CrossRef
17.
Melve KK, Skjaerven R, Oyen N. Families with a perinatal death: is there an association between the loss and the birthweight of surviving siblings? Paediatr Perinat Epidemiol. 2002;16(1):23–32.CrossRef
18.
Oyen N, Haglund B, Skjaerven R, Irgens LM. Maternal smoking, birthweight and gestational age in sudden infant death syndrome (SIDS) babies and their surviving siblings. Paediatr Perinat Epidemiol. 1997;11(Suppl 1):84–95.CrossRef
19.
Skjaerven R, Gjessing HK, Bakketeig LS. New standards for birth weight by gestational age using family data. Am J Obstet Gynecol. 2000;183(3):689–96.CrossRef
20.
Pedersen CB, Sun Y, Vestergaard M, Olsen J, Basso O. Assessing fetal growth impairments based on family data as a tool for identifying high-risk babies. An example with neonatal mortality. BMC Pregnancy Childbirth. 2007;7:28.CrossRef
21.
Wilcox MA, Chang AM, Johnson IR. The effects of parity on birthweight using successive pregnancies. Acta Obstet Gynecol Scand. 1996;75(5):459–3.CrossRef
22.
Hinkle SN, Albert PS, Mendola P, Sjaarda LA, Yeung E, Boghossian NS, et al. The association between parity and birthweight in a longitudinal consecutive pregnancy cohort. Paediatr Perinat Epidemiol. 2014;28(2):106–15.CrossRef
23.
Dor N, Mosberg H, Stern W, Jagani N, Schulman H. Complications in fetal macrosomia. N Y State J Med. 1984;84(6):302–5.PubMed
24.
Sack RA. The large infant. A study of maternal, obstetric, fetal, and newborn characteristics; including a long-term pediatric follow-up. Am J Obstet Gynecol. 1969;104(2):195–204.CrossRef
25.
Okun N, Verma A, Mitchell BF, Flowerdew G. Relative importance of maternal constitutional factors and glucose intolerance of pregnancy in the development of newborn macrosomia. J Matern Fetal Med. 1997;6(5):285–90.PubMed
26.
American College of Obstetricians and Gynecologists. Practice Bulletin No. 173: Fetal Macrosomia. Obstet Gynecol. 2016;128(5):e195–209.
27.
Zamorski MA, Biggs WS. Management of suspected fetal macrosomia. Am Fam Physician. 2001;63(2):302–6.PubMed
28.
Agbozo F, Abubakari A, Der J, Jahn A. Prevalence of low birth weight, macrosomia and stillbirth and their relationship to associated maternal risk factors in Hohoe municipality, Ghana. Midwifery. 2016;40:200–6.CrossRef
29.
Pei L, Kang Y, Zhao Y, Cheng Y, Yan H. Changes in socioeconomic inequality of low birth weight and Macrosomia in Shaanxi Province of Northwest China, 2010-2013: a cross-sectional study. Medicine (Baltimore). 2016;95(5):e2471.CrossRef
30.
Mohammadbeigi A, Farhadifar F, Soufi Zadeh N, Mohammadsalehi N, Rezaiee M, Aghaei M. Fetal macrosomia: risk factors, maternal, and perinatal outcome. Ann Med Health Sci Res. 2013;3(4):546–50.CrossRef
31.
Usta A, Usta CS, Yildiz A, Ozcaglayan R, Dalkiran ES, Savkli A, et al. Frequency of fetal macrosomia and the associated risk factors in pregnancies without gestational diabetes mellitus. Pan Afr Med J. 2017;26:62.CrossRef
Metadata
Title
Association between parity and macrosomia in Shaanxi Province of Northwest China
Authors
Fangliang Lei
Lili Zhang
Yuan Shen
Yaling Zhao
Yijun Kang
Pengfei Qu
Baibing Mi
Shaonong Dang
Hong Yan
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2020
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/s13052-020-0784-x

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