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Open Access 01-12-2019 | Endometriosis | Research

Risk factors for postoperative recurrence of ovarian endometriosis: long-term follow-up of 358 women

Authors: Xiao-Yan Li, Xiao-Pei Chao, Jin-Hua Leng, Wen Zhang, Jun-Ji Zhang, Yi Dai, Jing-Hua Shi, Shuang-Zheng Jia, Xiao-Xuan Xu, Si-Kai Chen, Yu-Shi Wu

Published in: Journal of Ovarian Research | Issue 1/2019

Abstract

Objective

To explore the risk factors for the recurrence of endometrioma and the risk factors for the recurrence of endometriosis-related pain after long-term follow-up.

Methods

This study retrospectively analyzed 358 women with endometriomas who had a minimum of 5-years follow up after laparoscopic endometrioma excision, which was performed at Peking Union Medical College Hospital from January 2009 to April 2013. All women were divided into recurrence group and nonrecurrence group. Analysis was performed with regard to preoperative history, laboratory analysis, findings during surgery, and symptoms during follow-up, including improvement and recurrence.

Results

The cumulative incidence rates of recurrence from 5 to 10 years after surgery were 15.4, 16.8, 19.3, 22.5, 22.5, and 22.5%, respectively. Significant differences were found between two groups in terms of age at surgery (RR: 0.764, 95% CI: 0.615–0.949, p = 0.015), duration of dysmenorrhea (RR: 1.120, 95% CI: 1.054–1.190, p < 0.001), presence of adenomyosis (RR: 1.629, 95% CI: 1.008–2.630, p = 0.046), CA125 level (RR: 1.856, 95% CI: 1.072–3.214, p = 0.021) and severity of dysmenorrhea. The severity of dysmenorrhea (RR: 1.711, 95% CI: 1.175–2.493, p = 0.005) and postoperative pregnancy (RR: 0.649, 95% CI: 0.460–0.914, p = 0.013) were significantly correlated with endometrioma recurrence in the multivariate analysis. No significant associations were found between the recurrence rate and gravida, parity, body mass index, infertility, leiomyoma presence, the size of ovarian endometrioma, the presence of deep infiltrating endometriosis, disease stage or postoperative medication.

Conclusions

The severity of dysmenorrhea and postoperative pregnancy were independent risk factors for the recurrence of ovarian endometriomas after surgery during the long-time follow up.

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Title: Risk factors for postoperative recurrence of ovarian endometriosis: long-term follow-up of 358 women
Authors: Xiao-Yan Li
Xiao-Pei Chao
Jin-Hua Leng
Wen Zhang
Jun-Ji Zhang
Yi Dai
Jing-Hua Shi
Shuang-Zheng Jia
Xiao-Xuan Xu
Si-Kai Chen
Yu-Shi Wu
Publication date: 01-12-2019
Publisher: BioMed Central
Keyword: Endometriosis
Published in: Journal of Ovarian Research / Issue 1/2019
Electronic ISSN: 1757-2215
DOI: https://doi.org/10.1186/s13048-019-0552-y

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Risk factors for postoperative recurrence of ovarian endometriosis: long-term follow-up of 358 women

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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