Published in:
Open Access
01-12-2019 | Conventional Pacemaker | Letter to the Editor
Negative screening of Fabry disease in patients with conduction disorders requiring a pacemaker
Authors:
Ángela López-Sainz, Vicente Climent, Tomas Ripoll-Vera, Maria Angeles Espinosa, Roberto Barriales-Villa, Marina Navarro, Javier Limeres, Diana Domingo, David C. Kasper, Pablo Garcia-Pavia
Published in:
Orphanet Journal of Rare Diseases
|
Issue 1/2019
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Abstract
Identification of Fabry disease (FD) in cardiac patients has been restricted so far to patients with left ventricular hypertrophy. Conduction problems are frequent in FD and could precede other manifestations, offering a possible earlier diagnosis.
We studied the prevalence of FD in 188 patients < 70 years with conduction problems requiring pacemaker implantation. Although classical manifestations of FD were not rare, no patient with FD was identified. Screening efforts should not be conducted in this population.