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Journal of Orthopaedic Surgery and Research
Published in: Journal of Orthopaedic Surgery and Research 1/2021

Open Access 01-12-2021 | Osteoporosis | Systematic review

Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis

Authors: Nader Salari, Niloofar Darvishi, Yalda Bartina, Mojdeh Larti, Aliakbar Kiaei, Mahvan Hemmati, Shamarina Shohaimi, Masoud Mohammadi

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2021

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Abstract

Background

Osteoporosis is one of the most common bone system diseases that is associated with an increased risk of bone fractures and causes many complications for patients. With age, the prevalence of this disease increases so that it has become a serious problem among the elders. In this study, the prevalence of osteoporosis among elders around the world is examined to gain an understanding of its prevalence pattern.

Methods

In this systematic review and meta-analysis, articles that have focused on prevalence of osteoporosis in the world’s elders were searched with these key words, such as Prevalence, Osteoporosis, Elders, Older adult in the Science Direct, Embase, Scopus, PubMed, Web of Science (WoS) databases and Google Scholar search engine, and extracted without time limit until March 2020 and transferred to information management software (EndNote). Then, duplicate studies were eliminated and the remaining studies were evaluated in terms of screening, competence and qualitative evaluation based on inclusion and exclusion criteria. Data analysis was performed with Comprehensive Meta-Analysis software (Version 2) and Begg and Mazumdar test was used to check the publication bias and I2 test was used to check the heterogeneity.

Results

In a review of 40 studies (31 studies related to Asia, 5 studies related to Europe and 4 studies related to America) with a total sample size of 79,127 people, the prevalence of osteoporosis in the elders of the world; 21.7% (95% confidence interval: 18.8–25%) and the overall prevalence of osteoporosis in older men and women in the world, 35.3% (95% confidence interval: 27.9–43.4%), 12.5% (95% confidence interval: 9.3–16.7%) was reported. Also, the highest prevalence of osteoporosis in the elders was reported in Asia with; 24.3% (95% confidence interval: 20.9–28.1%).

Conclusion

The results of the present study showed that the prevalence of osteoporosis in the elders and especially elders' women is very high. Osteoporosis was once thought to be an inseparable part of elders’ lives. Nowadays, Osteoporosis can be prevented due to significant scientific advances in its causes, diagnosis, and treatment. Regarding the growing number of elderly people in the world, it is necessary for health policy-makers to think of measures to prevent and treat osteoporosis among the elders.
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Metadata
Title
Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis
Authors
Nader Salari
Niloofar Darvishi
Yalda Bartina
Mojdeh Larti
Aliakbar Kiaei
Mahvan Hemmati
Shamarina Shohaimi
Masoud Mohammadi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2021
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-021-02821-8

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