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Published in: Journal of Orthopaedic Surgery and Research 1/2016

Open Access 01-12-2016 | Research article

Analysis of the independent risk factors of neurologic deficit after thoracolumbar burst fracture

Authors: Peifu Tang, Anhua Long, Tao Shi, Licheng Zhang, Lihai Zhang

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2016

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Abstract

Background

The objective of this study is to identify the independent risk factors of neurologic deficit after thoracolumbar burst fracture. Traumatic fractures of the thoracolumbar spine are the most common type of spinal column fractures. Many studies have attempted to determine whether neurologic deficit in such fractures is related to spinal canal stenosis or other parameters observed on axial computed tomography. However, this relationship remains controversial.

Methods

A review of the clinical data and axial computed tomography (CT) for 105 patients was performed. Neurologic deficit was classified according to the American Spinal Injury Association (ASIA) classification. Various preoperative CT parameters, including vertebral body compression, canal stenosis, sagittal alignment, and fragment reverse, were analyzed using ordinal logistic regression analysis.

Results

Arbeitsgemeinschaft für Osteosynthesefragen (AO) classification, canal volume, transverse canal diameter, median sagittal diameter, Cobb angle, compression ratio of the sagittal diameter, compression ratio of the cross-sectional area, and compression ratios of the anterior vertebral height (AVH), middle vertebral height (MVH), and posterior vertebral height (PVH) were significantly associated with severity of nerve injury (P < 0.05). However, flip angle and rotation angle of bony fragments were unrelated to severity of nerve damage. Multivariate logistic regression identified AO classification, compression ratio of median sagittal diameter, anterior vertebral compression ratio, and distance from the posterior margin to the vertebral body above to be independent variables associated with neurologic deficit.

Conclusions

The four CT parameters most strongly associated with neurologic deficit in thoracolumbar burst fractures are AO classification, compression ratio of median sagittal diameter, anterior vertebral compression ratio, and distance from the posterior margin to the vertebral body above.
Literature
1.
go back to reference Denis F. The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983;8(8):817–31.CrossRefPubMed Denis F. The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983;8(8):817–31.CrossRefPubMed
2.
go back to reference Trafton PG, Boyd Jr CA. Computed tomography of thoracic and lumbar spine injuries. J Trauma. 1984;24(6):506–15.CrossRefPubMed Trafton PG, Boyd Jr CA. Computed tomography of thoracic and lumbar spine injuries. J Trauma. 1984;24(6):506–15.CrossRefPubMed
3.
go back to reference Vaccaro AR, Nachwalter RS, Klein GR, Sewards JM, Albert TJ, Garfin SR. The significance of thoracolumbar spinal canal size in spinal cord injury patients. Spine. 2001;26(4):371–6.CrossRefPubMed Vaccaro AR, Nachwalter RS, Klein GR, Sewards JM, Albert TJ, Garfin SR. The significance of thoracolumbar spinal canal size in spinal cord injury patients. Spine. 2001;26(4):371–6.CrossRefPubMed
4.
go back to reference Fontijne WP, de Klerk LW, Braakman R, Stijnen T, Tanghe HL, Steenbeek R, van Linge B. CT scan prediction of neurological deficit in thoracolumbar burst fractures. J Bone Joint Surg Br Vol. 1992;74(5):683–5. Fontijne WP, de Klerk LW, Braakman R, Stijnen T, Tanghe HL, Steenbeek R, van Linge B. CT scan prediction of neurological deficit in thoracolumbar burst fractures. J Bone Joint Surg Br Vol. 1992;74(5):683–5.
5.
go back to reference HASHIMOTO T, KANEDA K, ABUMI K. Relationship between traumatic spinal canal stenosis and neurologic deficits in thoracolumbar burst fractures. Spine. 1988;13(11):1268–72.CrossRefPubMed HASHIMOTO T, KANEDA K, ABUMI K. Relationship between traumatic spinal canal stenosis and neurologic deficits in thoracolumbar burst fractures. Spine. 1988;13(11):1268–72.CrossRefPubMed
6.
go back to reference Kim NH, Lee HM, Chun IM. Neurologic injury and recovery in patients with burst fracture of the thoracolumbar spine. Spine. 1999;24(3):290–3. discussion 4.CrossRefPubMed Kim NH, Lee HM, Chun IM. Neurologic injury and recovery in patients with burst fracture of the thoracolumbar spine. Spine. 1999;24(3):290–3. discussion 4.CrossRefPubMed
7.
go back to reference Meves R, Avanzi O. Correlation among canal compromise, neurologic deficit, and injury severity in thoracolumbar burst fractures. Spine. 2006;31(18):2137–41.CrossRefPubMed Meves R, Avanzi O. Correlation among canal compromise, neurologic deficit, and injury severity in thoracolumbar burst fractures. Spine. 2006;31(18):2137–41.CrossRefPubMed
8.
go back to reference Meves R, Avanzi O. Correlation between neurological deficit and spinal canal compromise in 198 patients with thoracolumbar and lumbar fractures. Spine. 2005;30(7):787–91.CrossRefPubMed Meves R, Avanzi O. Correlation between neurological deficit and spinal canal compromise in 198 patients with thoracolumbar and lumbar fractures. Spine. 2005;30(7):787–91.CrossRefPubMed
9.
go back to reference Mohanty S, Bhat N, Abraham R, Keerthi CI. Neurological deficit and canal compromise in thoracolumbar and lumbar burst fractures. J Orthop Surg. 2008;16(1):20–3.CrossRef Mohanty S, Bhat N, Abraham R, Keerthi CI. Neurological deficit and canal compromise in thoracolumbar and lumbar burst fractures. J Orthop Surg. 2008;16(1):20–3.CrossRef
10.
go back to reference Yugue I, Aono K, Shiba K, Ueta T, Maeda T, Mori E, Kawano O. Analysis of the risk factors for severity of neurologic status in 216 patients with thoracolumbar and lumbar burst fractures. Spine. 2011;36(19):1563–9.CrossRefPubMed Yugue I, Aono K, Shiba K, Ueta T, Maeda T, Mori E, Kawano O. Analysis of the risk factors for severity of neurologic status in 216 patients with thoracolumbar and lumbar burst fractures. Spine. 2011;36(19):1563–9.CrossRefPubMed
11.
go back to reference Isomi T, Panjabi MM, Kato Y, Wang JL. Radiographic parameters for evaluating the neurological spaces in experimental thoracolumbar burst fractures. J Spinal Disord. 2000;13(5):404–11.CrossRefPubMed Isomi T, Panjabi MM, Kato Y, Wang JL. Radiographic parameters for evaluating the neurological spaces in experimental thoracolumbar burst fractures. J Spinal Disord. 2000;13(5):404–11.CrossRefPubMed
12.
go back to reference Keynan O, Fisher CG, Vaccaro A, Fehlings MG, Oner FC, Dietz J, Kwon B, Rampersaud R, Bono C, France J, Dvorak M. Radiographic measurement parameters in thoracolumbar fractures: a systematic review and consensus statement of the spine trauma study group. Spine. 2006;31(5):E156–65.CrossRefPubMed Keynan O, Fisher CG, Vaccaro A, Fehlings MG, Oner FC, Dietz J, Kwon B, Rampersaud R, Bono C, France J, Dvorak M. Radiographic measurement parameters in thoracolumbar fractures: a systematic review and consensus statement of the spine trauma study group. Spine. 2006;31(5):E156–65.CrossRefPubMed
13.
go back to reference Vaccaro AR, Rihn JA, Saravanja D, Anderson DG, Hilibrand AS, Albert TJ, Fehlings MG, Morrison W, Flanders AE, France JC, Arnold P, Anderson PA, Friel B, Malfair D, Street J, Kwon B, Paquette S, Boyd M, Dvorak MF, Fisher C. Injury of the posterior ligamentous complex of the thoracolumbar spine: a prospective evaluation of the diagnostic accuracy of magnetic resonance imaging. Spine. 2009;34(23):E841–7.CrossRefPubMed Vaccaro AR, Rihn JA, Saravanja D, Anderson DG, Hilibrand AS, Albert TJ, Fehlings MG, Morrison W, Flanders AE, France JC, Arnold P, Anderson PA, Friel B, Malfair D, Street J, Kwon B, Paquette S, Boyd M, Dvorak MF, Fisher C. Injury of the posterior ligamentous complex of the thoracolumbar spine: a prospective evaluation of the diagnostic accuracy of magnetic resonance imaging. Spine. 2009;34(23):E841–7.CrossRefPubMed
14.
go back to reference Mavrogenis A, Tsibidakis H, Papagelopoulos P, Antonopoulos D, Papathanasiou J, Korres D, Pneumaticos S. Posterior transpedicular decompression for thoracolumbar burst fractures. Folia Med (Plovdiv). 2010;52(4):39–47. Mavrogenis A, Tsibidakis H, Papagelopoulos P, Antonopoulos D, Papathanasiou J, Korres D, Pneumaticos S. Posterior transpedicular decompression for thoracolumbar burst fractures. Folia Med (Plovdiv). 2010;52(4):39–47.
15.
go back to reference Alpantaki K, Bano A, Pasku D, Mavrogenis AF, Papagelopoulos PJ, Sapkas GS, Korres DS, Katonis P. Thoracolumbar burst fractures: a systematic review of management. Orthopedics. 2010;33(6):422–9.CrossRefPubMed Alpantaki K, Bano A, Pasku D, Mavrogenis AF, Papagelopoulos PJ, Sapkas GS, Korres DS, Katonis P. Thoracolumbar burst fractures: a systematic review of management. Orthopedics. 2010;33(6):422–9.CrossRefPubMed
16.
go back to reference Katonis P, Pasku D, Alpantaki K, Mavrogenis AF, Korres DS, Sapkas GS, Papagelopoulos PJ. Combination of the AO-Magerl and load-sharing classifications for the management of thoracolumbar burst fractures. Orthopedics. 2010;33(3). doi:10.3928/01477447-20100129-07. Epub 2010 Mar 10. Katonis P, Pasku D, Alpantaki K, Mavrogenis AF, Korres DS, Sapkas GS, Papagelopoulos PJ. Combination of the AO-Magerl and load-sharing classifications for the management of thoracolumbar burst fractures. Orthopedics. 2010;33(3). doi:10.​3928/​01477447-20100129-07. Epub 2010 Mar 10.
17.
go back to reference Willen J, Anderson J, Toomoka K, Singer K. The natural history of burst fractures at the thoracolumbar junction. J Spinal Disord Tech. 1990;3(1):39–46. Willen J, Anderson J, Toomoka K, Singer K. The natural history of burst fractures at the thoracolumbar junction. J Spinal Disord Tech. 1990;3(1):39–46.
18.
go back to reference RASMUSSEN PA, RABIN MH, MANN DC, PERL JR, LORENZ MA, VRBOS LA. Reduced transverse spinal area secondary to burst fractures: is there a relationship to neurologic injury? J Neurotrauma. 1994;11(6):711–20.CrossRefPubMed RASMUSSEN PA, RABIN MH, MANN DC, PERL JR, LORENZ MA, VRBOS LA. Reduced transverse spinal area secondary to burst fractures: is there a relationship to neurologic injury? J Neurotrauma. 1994;11(6):711–20.CrossRefPubMed
19.
go back to reference Leferink VJ, Nijboer JM, Zimmerman KW, Veldhuis EF, ten Vergert EM, ten Duis HJ. Burst fractures of the thoracolumbar spine: changes of the spinal canal during operative treatment and follow-up. Eur Spine J. 2003;12(3):255–60.PubMed Leferink VJ, Nijboer JM, Zimmerman KW, Veldhuis EF, ten Vergert EM, ten Duis HJ. Burst fractures of the thoracolumbar spine: changes of the spinal canal during operative treatment and follow-up. Eur Spine J. 2003;12(3):255–60.PubMed
20.
go back to reference Bridwell KH, Kuklo TR, Lewis SJ, Sweet FA, Lenke LG, Baldus C. String test measurement to assess the effect of spinal deformity correction on spinal canal length. Spine. 2001;26(18):2013–9.CrossRefPubMed Bridwell KH, Kuklo TR, Lewis SJ, Sweet FA, Lenke LG, Baldus C. String test measurement to assess the effect of spinal deformity correction on spinal canal length. Spine. 2001;26(18):2013–9.CrossRefPubMed
21.
go back to reference Verlaan JJ, van de Kraats EB, van Walsum T, Dhert WJ, Oner FC, Niessen WJ. Three-dimensional rotational X-ray imaging for spine surgery: a quantitative validation study comparing reconstructed images with corresponding anatomical sections. Spine. 2005;30(5):556–61.CrossRefPubMed Verlaan JJ, van de Kraats EB, van Walsum T, Dhert WJ, Oner FC, Niessen WJ. Three-dimensional rotational X-ray imaging for spine surgery: a quantitative validation study comparing reconstructed images with corresponding anatomical sections. Spine. 2005;30(5):556–61.CrossRefPubMed
22.
go back to reference Beck M, Mittlmeier T, Gierer P, Rotter R, Harms C, Gradl G. Which is the ideal point of time to perform intraoperative 3D imaging in dorsal stabilisation of thoracolumbar spine fractures? A matched pair analysis. Injury. 2010;41(10):996–1001.CrossRefPubMed Beck M, Mittlmeier T, Gierer P, Rotter R, Harms C, Gradl G. Which is the ideal point of time to perform intraoperative 3D imaging in dorsal stabilisation of thoracolumbar spine fractures? A matched pair analysis. Injury. 2010;41(10):996–1001.CrossRefPubMed
23.
go back to reference Hott JS, Papadopoulos SM, Theodore N, Dickman CA, Sonntag VK. Intraoperative Iso-C C-arm navigation in cervical spinal surgery: review of the first 52 cases. Spine. 2004;29(24):2856–60.CrossRefPubMed Hott JS, Papadopoulos SM, Theodore N, Dickman CA, Sonntag VK. Intraoperative Iso-C C-arm navigation in cervical spinal surgery: review of the first 52 cases. Spine. 2004;29(24):2856–60.CrossRefPubMed
24.
go back to reference Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian S. A comprehensive classification of thoracic and lumbar injuries. Eur Spine J. 1994;3(4):184–201.CrossRefPubMed Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian S. A comprehensive classification of thoracic and lumbar injuries. Eur Spine J. 1994;3(4):184–201.CrossRefPubMed
25.
go back to reference Maynard Jr FM, Bracken MB, Creasey G, Ditunno Jr JF, Donovan WH, Ducker TB, Garber SL, Marino RJ, Stover SL, Tator CH, Waters RL, Wilberger JE, Young W. International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association. Spinal cord May. 1997;35(5):266–74.CrossRef Maynard Jr FM, Bracken MB, Creasey G, Ditunno Jr JF, Donovan WH, Ducker TB, Garber SL, Marino RJ, Stover SL, Tator CH, Waters RL, Wilberger JE, Young W. International Standards for Neurological and Functional Classification of Spinal Cord Injury. American Spinal Injury Association. Spinal cord May. 1997;35(5):266–74.CrossRef
26.
go back to reference Guerra Jr J, Garfin SR, Resnick D. Vertebral burst fractures: CT analysis of the retropulsed fragment. Radiology. 1984;153(3):769–72.CrossRefPubMed Guerra Jr J, Garfin SR, Resnick D. Vertebral burst fractures: CT analysis of the retropulsed fragment. Radiology. 1984;153(3):769–72.CrossRefPubMed
27.
go back to reference Cobb J. The American Academy of Orthopedic Surgeons Instructional Course Lectures. Ann Arbor: Edwards; 1948. Cobb J. The American Academy of Orthopedic Surgeons Instructional Course Lectures. Ann Arbor: Edwards; 1948.
Metadata
Title
Analysis of the independent risk factors of neurologic deficit after thoracolumbar burst fracture
Authors
Peifu Tang
Anhua Long
Tao Shi
Licheng Zhang
Lihai Zhang
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2016
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-016-0448-0

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