Skip to main content
Top
Published in: World Journal of Emergency Surgery 1/2017

Open Access 01-12-2017 | Research article

Low values of central venous oxygen saturation (ScvO2) during surgery and anastomotic leak of abdominal trauma patients

Authors: Andres Isaza-Restrepo, Jose F. Moreno-Mejia, Juan S. Martin-Saavedra, Milciades Ibañez-Pinilla

Published in: World Journal of Emergency Surgery | Issue 1/2017

Login to get access

Abstract

Background

There is a well known relationship between hypoperfusion and postoperative complications like anastomotic leak. No studies have been done addressing this relationship in the context of abdominal trauma surgery. Central venous oxygen saturation is an important hypoperfusion marker of potential use in abdominal trauma surgery for identifying the risk of anastomotic leak development. The purpose of this study was to identify the relationship between low values of central venous oxygen saturation and anastomotic leak of gastrointestinal sutures in the postoperative period in abdominal trauma surgery.

Methods

A cross-sectional prospective study was performed. Patients over 14 years old who required surgical gastrointestinal repair secondary to abdominal trauma were included. Anastomotic leak diagnosis was confirmed through clinical manifestations and diagnostic images or secondary surgery when needed. Central venous oxygen blood saturation was measured at the beginning of surgery through a central catheter. Demographic data, trauma mechanism, anatomic site of trauma, hemoglobin levels, abdominal trauma index, and comorbidities were assessed as secondary variables.

Results

Patients who developed anastomotic leak showed lower mean central venous oxygen saturation levels (60.0% ± 2.94%) than those who did not (69.89% ± 7.21%) (p = 0.010).

Conclusions

Central venous oxygen saturation <65% was associated with the development of gastrointestinal leak during postoperative time of patients who underwent surgery secondary to abdominal trauma.
Literature
1.
go back to reference Kingham TP, Pachter HL. Colonic anastomotic leak: risk factors, diagnosis, and treatment. J Am Coll Surg. 2009;208(2):269–78.CrossRefPubMed Kingham TP, Pachter HL. Colonic anastomotic leak: risk factors, diagnosis, and treatment. J Am Coll Surg. 2009;208(2):269–78.CrossRefPubMed
2.
go back to reference Paterno F, Longo WE. The etiology and pathogenesis of vascular disorders of the intestine. Radiol Clin N Am. 2008;46:877–85.CrossRefPubMed Paterno F, Longo WE. The etiology and pathogenesis of vascular disorders of the intestine. Radiol Clin N Am. 2008;46:877–85.CrossRefPubMed
3.
go back to reference Vignali A, Gianotti L, Braga M, Radaelli G, Malvezzi L, Di Carlo V. Altered microperfusion at the rectal stump is predictive for rectal anastomotic leak. Dis Colon Rectum. 2000;43(1):76–82.CrossRefPubMed Vignali A, Gianotti L, Braga M, Radaelli G, Malvezzi L, Di Carlo V. Altered microperfusion at the rectal stump is predictive for rectal anastomotic leak. Dis Colon Rectum. 2000;43(1):76–82.CrossRefPubMed
4.
go back to reference Scalea TM, Holman M, Fuortes M, Baron BJ, Phillips TF, Goldstein AS, et al. Central venous blood oxygen saturation: an early, accurate measurement of volume during hemorrhage. J Trauma. 1988;28(6):725–32.CrossRefPubMed Scalea TM, Holman M, Fuortes M, Baron BJ, Phillips TF, Goldstein AS, et al. Central venous blood oxygen saturation: an early, accurate measurement of volume during hemorrhage. J Trauma. 1988;28(6):725–32.CrossRefPubMed
5.
go back to reference Scalea TM, Hartnett RW, Duncan AO, Atweh NA, Phillips TF, Sclafani SJ, et al. Central venous oxygen saturation: a useful clinical tool in trauma patients. J Trauma. 1990;30(12):1539–43.CrossRefPubMed Scalea TM, Hartnett RW, Duncan AO, Atweh NA, Phillips TF, Sclafani SJ, et al. Central venous oxygen saturation: a useful clinical tool in trauma patients. J Trauma. 1990;30(12):1539–43.CrossRefPubMed
6.
go back to reference Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345(19):1368–77.CrossRefPubMed Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345(19):1368–77.CrossRefPubMed
8.
go back to reference Teboul JL, Hamzaoui O, Monnet X. SvO2 to monitor resuscitation of septic patients: let’s just understand the basic physiology. Crit Care. 2011;15:1005. England.CrossRefPubMedPubMedCentral Teboul JL, Hamzaoui O, Monnet X. SvO2 to monitor resuscitation of septic patients: let’s just understand the basic physiology. Crit Care. 2011;15:1005. England.CrossRefPubMedPubMedCentral
9.
go back to reference Permpikul C, Sringam P, Tongyoo S. Therapeutic goal achievements during severe sepsis and septic shock resuscitation and their association with patients’ outcomes. J Med Assoc Thai. 2014;97 Suppl 3:S176–83.PubMed Permpikul C, Sringam P, Tongyoo S. Therapeutic goal achievements during severe sepsis and septic shock resuscitation and their association with patients’ outcomes. J Med Assoc Thai. 2014;97 Suppl 3:S176–83.PubMed
10.
go back to reference Mohajeri G, Tabatabaei A, Hashemi M, Bistgani MM. Relationship of venous blood gas with cervical esophagogastric anastomotic leak. Asian Cardiovasc Thorac Ann. 2012;20:566–9. England.CrossRefPubMed Mohajeri G, Tabatabaei A, Hashemi M, Bistgani MM. Relationship of venous blood gas with cervical esophagogastric anastomotic leak. Asian Cardiovasc Thorac Ann. 2012;20:566–9. England.CrossRefPubMed
11.
go back to reference Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED. Changes in central venous saturation after major surgery, and association with outcome. Crit Care. 2005;9(6):R694–9.CrossRefPubMedPubMedCentral Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED. Changes in central venous saturation after major surgery, and association with outcome. Crit Care. 2005;9(6):R694–9.CrossRefPubMedPubMedCentral
12.
go back to reference Giraud R, Siegenthaler N, Gayet-Ageron A, Combescure C, Romand JA, Bendjelid K. ScvO(2) as a marker to define fluid responsiveness. J Trauma. 2011;70(4):802–7.CrossRefPubMed Giraud R, Siegenthaler N, Gayet-Ageron A, Combescure C, Romand JA, Bendjelid K. ScvO(2) as a marker to define fluid responsiveness. J Trauma. 2011;70(4):802–7.CrossRefPubMed
13.
go back to reference Reinhart K, Rudolph T, Bredle DL, Hannemann L, Cain SM. Comparison of central-venous to mixed-venous oxygen saturation during changes in oxygen supply/demand. Chest. 1989;95(6):1216–21.CrossRefPubMed Reinhart K, Rudolph T, Bredle DL, Hannemann L, Cain SM. Comparison of central-venous to mixed-venous oxygen saturation during changes in oxygen supply/demand. Chest. 1989;95(6):1216–21.CrossRefPubMed
14.
15.
go back to reference Hosking C, Wilander P, Goosen J, Jacobson H, Moeng M, Boffard K, et al. Low central venous oxygen saturation in haemodynamically stabilized trauma patients is associated with poor outcome. Acta Anaesthesiol Scand. 2011;55(6):713–21.CrossRefPubMed Hosking C, Wilander P, Goosen J, Jacobson H, Moeng M, Boffard K, et al. Low central venous oxygen saturation in haemodynamically stabilized trauma patients is associated with poor outcome. Acta Anaesthesiol Scand. 2011;55(6):713–21.CrossRefPubMed
16.
go back to reference Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J. Lactate clearance and survival following injury. J Trauma. 1993;35(4):584–8. discussion 8-9.CrossRefPubMed Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J. Lactate clearance and survival following injury. J Trauma. 1993;35(4):584–8. discussion 8-9.CrossRefPubMed
17.
go back to reference Husain FA, Martin MJ, Mullenix PS, Steele SR, Elliott DC. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg. 2003;185(5):485–91.CrossRefPubMed Husain FA, Martin MJ, Mullenix PS, Steele SR, Elliott DC. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg. 2003;185(5):485–91.CrossRefPubMed
18.
go back to reference Rixen D, Siegel JH. Bench-to-bedside review: oxygen debt and its metabolic correlates as quantifiers of the severity of hemorrhagic and post-traumatic shock. Crit Care. 2005;9(5):441–53.CrossRefPubMedPubMedCentral Rixen D, Siegel JH. Bench-to-bedside review: oxygen debt and its metabolic correlates as quantifiers of the severity of hemorrhagic and post-traumatic shock. Crit Care. 2005;9(5):441–53.CrossRefPubMedPubMedCentral
19.
go back to reference Winters ME, McCurdy MT, Zilberstein J. Monitoring the critically ill emergency department patient. Emerg Med Clin North Am. 2008;26(3):741–57. ix.CrossRefPubMed Winters ME, McCurdy MT, Zilberstein J. Monitoring the critically ill emergency department patient. Emerg Med Clin North Am. 2008;26(3):741–57. ix.CrossRefPubMed
20.
go back to reference Kusano C, Baba M, Takao S, Sane S, Shimada M, Shirao K, et al. Oxygen delivery as a factor in the development of fatal postoperative complications after oesophagectomy. Br J Surg. 1997;84(2):252–7.CrossRefPubMed Kusano C, Baba M, Takao S, Sane S, Shimada M, Shirao K, et al. Oxygen delivery as a factor in the development of fatal postoperative complications after oesophagectomy. Br J Surg. 1997;84(2):252–7.CrossRefPubMed
21.
go back to reference Bland RD, Shoemaker WC, Abraham E, Cobo JC. Hemodynamic and oxygen transport patterns in surviving and nonsurviving postoperative patients. Crit Care Med. 1985;13(2):85–90.CrossRefPubMed Bland RD, Shoemaker WC, Abraham E, Cobo JC. Hemodynamic and oxygen transport patterns in surviving and nonsurviving postoperative patients. Crit Care Med. 1985;13(2):85–90.CrossRefPubMed
22.
go back to reference Peerless JR, Alexander JJ, Pinchak AC, Piotrowski JJ, Malangoni MA. Oxygen delivery is an important predictor of outcome in patients with ruptured abdominal aortic aneurysms. Ann Surg. 1998;227(5):726–32. discussion 32-4.CrossRefPubMedPubMedCentral Peerless JR, Alexander JJ, Pinchak AC, Piotrowski JJ, Malangoni MA. Oxygen delivery is an important predictor of outcome in patients with ruptured abdominal aortic aneurysms. Ann Surg. 1998;227(5):726–32. discussion 32-4.CrossRefPubMedPubMedCentral
23.
go back to reference Poeze M, Ramsay G, Greve JW, Singer M. Prediction of postoperative cardiac surgical morbidity and organ failure within 4 hours of intensive care unit admission using esophageal Doppler ultrasonography. Crit Care Med. 1999;27(7):1288–94.CrossRefPubMed Poeze M, Ramsay G, Greve JW, Singer M. Prediction of postoperative cardiac surgical morbidity and organ failure within 4 hours of intensive care unit admission using esophageal Doppler ultrasonography. Crit Care Med. 1999;27(7):1288–94.CrossRefPubMed
24.
go back to reference Shoemaker WC, Montgomery ES, Kaplan E, Elwyn DH. Physiologic patterns in surviving and nonsurviving shock patients. Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg. 1973;106(5):630–6.CrossRefPubMed Shoemaker WC, Montgomery ES, Kaplan E, Elwyn DH. Physiologic patterns in surviving and nonsurviving shock patients. Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg. 1973;106(5):630–6.CrossRefPubMed
25.
go back to reference Futier E, Constantin JM, Petit A, Chanques G, Kwiatkowski F, Flamein R, et al. Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: a prospective randomized trial. Arch Surg. 2010;145:1193–200. United States.CrossRefPubMed Futier E, Constantin JM, Petit A, Chanques G, Kwiatkowski F, Flamein R, et al. Conservative vs restrictive individualized goal-directed fluid replacement strategy in major abdominal surgery: a prospective randomized trial. Arch Surg. 2010;145:1193–200. United States.CrossRefPubMed
26.
go back to reference Schmelzer TM, Perron AD, Thomason MH, Sing RF. A comparison of central venous and arterial base deficit as a predictor of survival in acute trauma. Am J Emerg Med. 2008;26(2):119–23.CrossRefPubMed Schmelzer TM, Perron AD, Thomason MH, Sing RF. A comparison of central venous and arterial base deficit as a predictor of survival in acute trauma. Am J Emerg Med. 2008;26(2):119–23.CrossRefPubMed
27.
go back to reference Hwang RF, Schwartz RW. Enterocutaneous fistulas: current diagnosis and management. Curr Surg. 2000;57(5):443–5.CrossRefPubMed Hwang RF, Schwartz RW. Enterocutaneous fistulas: current diagnosis and management. Curr Surg. 2000;57(5):443–5.CrossRefPubMed
28.
go back to reference Dudrick SJ, Wilmore DW, Vars HM, Rhoads JE. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance. Surgery. 1968;64(1):134–42.PubMed Dudrick SJ, Wilmore DW, Vars HM, Rhoads JE. Long-term total parenteral nutrition with growth, development, and positive nitrogen balance. Surgery. 1968;64(1):134–42.PubMed
30.
go back to reference Terzi C, Egeli T, Canda AE, Arslan NC. Management of enteroatmospheric fistulae. Int Wound J. 2014;11 Suppl 1:17–21.CrossRefPubMed Terzi C, Egeli T, Canda AE, Arslan NC. Management of enteroatmospheric fistulae. Int Wound J. 2014;11 Suppl 1:17–21.CrossRefPubMed
31.
go back to reference Mayorga M. Estrategias para mejorar la sobrevivencia de los pacientes con sepsis severa/Strategies for improving survival in patients with severe sepsis. Lima: Colegio Médico del Perú; 2010. p. 302. Mayorga M. Estrategias para mejorar la sobrevivencia de los pacientes con sepsis severa/Strategies for improving survival in patients with severe sepsis. Lima: Colegio Médico del Perú; 2010. p. 302.
32.
go back to reference Cecconi M, Corredor C, Arulkumaran N, Abuella G, Ball J, Grounds RM, et al. Clinical review: goal-directed therapy-what is the evidence in surgical patients? The effect on different risk groups. Crit Care. 2013;17:209. England.CrossRefPubMedPubMedCentral Cecconi M, Corredor C, Arulkumaran N, Abuella G, Ball J, Grounds RM, et al. Clinical review: goal-directed therapy-what is the evidence in surgical patients? The effect on different risk groups. Crit Care. 2013;17:209. England.CrossRefPubMedPubMedCentral
35.
Metadata
Title
Low values of central venous oxygen saturation (ScvO2) during surgery and anastomotic leak of abdominal trauma patients
Authors
Andres Isaza-Restrepo
Jose F. Moreno-Mejia
Juan S. Martin-Saavedra
Milciades Ibañez-Pinilla
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2017
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-017-0139-0

Other articles of this Issue 1/2017

World Journal of Emergency Surgery 1/2017 Go to the issue