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Published in: Radiation Oncology 1/2016

Open Access 01-12-2016 | Review

Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors

Authors: Lu Guo, Gang Wang, Yuanming Feng, Tonggang Yu, Yu Guo, Xu Bai, Zhaoxiang Ye

Published in: Radiation Oncology | Issue 1/2016

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Abstract

Accurate target volume delineation is crucial for the radiotherapy of tumors. Diffusion and perfusion magnetic resonance imaging (MRI) can provide functional information about brain tumors, and they are able to detect tumor volume and physiological changes beyond the lesions shown on conventional MRI. This review examines recent studies that utilized diffusion and perfusion MRI for tumor volume definition in radiotherapy of brain tumors, and it presents the opportunities and challenges in the integration of multimodal functional MRI into clinical practice. The results indicate that specialized and robust post-processing algorithms and tools are needed for the precise alignment of targets on the images, and comprehensive validations with more clinical data are important for the improvement of the correlation between histopathologic results and MRI parameter images.
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Metadata
Title
Diffusion and perfusion weighted magnetic resonance imaging for tumor volume definition in radiotherapy of brain tumors
Authors
Lu Guo
Gang Wang
Yuanming Feng
Tonggang Yu
Yu Guo
Xu Bai
Zhaoxiang Ye
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2016
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/s13014-016-0702-y

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