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Radiation Oncology
Published in: Radiation Oncology 1/2015

Open Access 01-12-2015 | Research

Three-dimensional verification of 125I seed stability after permanent implantation in the parotid gland and periparotid region

Authors: Yi Fan, Ming-Wei Huang, Lei Zheng, Yi-Jiao Zhao, Jian-Guo Zhang

Published in: Radiation Oncology | Issue 1/2015

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Abstract

Objective

To evaluate seed stability after permanent implantation in the parotid gland and periparotid region via a three-dimensional reconstruction of CT data.

Material and methods

Fifteen patients treated from June 2008 to June 2012 at Peking University School and Hospital of Stomatology for parotid gland tumors with postoperative adjunctive 125I interstitial brachytherapy were retrospectively reviewed in this study. Serial CT data were obtained during follow-up. Mimics and Geomagic Studio software were used for seed reconstruction and stability analysis, respectively.

Results

Seed loss and/or migration outside of the treated area were absent in all patients during follow-up (23–71 months). Total seed cluster volume was maximized on day 1 post-implantation due to edema and decreased significantly by an average of 13.5 % (SD = 9.80 %; 95 % CI, 6.82–17.68 %) during the first two months and an average of 4.5 % (SD = 3.60 %; 95 % CI, 2.29–6.29 %) during the next four months. Volume stabilized over the subsequent six months.

Conclusions

125I seed number and location were stable with a general volumetric shrinkage tendency in the parotid gland and periparotid region. Three-dimensional seed reconstruction of CT images is feasible for visualization and verification of implanted seeds in parotid brachytherapy.
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Metadata
Title
Three-dimensional verification of 125I seed stability after permanent implantation in the parotid gland and periparotid region
Authors
Yi Fan
Ming-Wei Huang
Lei Zheng
Yi-Jiao Zhao
Jian-Guo Zhang
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2015
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/s13014-015-0552-z

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