Skip to main content
Top
Published in: Implementation Science 1/2015

Open Access 01-12-2016 | Systematic review

Barriers and enablers to guideline implementation strategies to improve obstetric care practice in low- and middle-income countries: a systematic review of qualitative evidence

Authors: Tim Stokes, Elizabeth J. Shaw, Janette Camosso-Stefinovic, Mari Imamura, Lovney Kanguru, Julia Hussein

Published in: Implementation Science | Issue 1/2015

Login to get access

Abstract

Background

Maternal mortality remains a major international health problem in low- and middle-income countries (LMIC), and most could have been prevented by quality improvement interventions already demonstrated to be effective, such as clinical guideline implementation strategies. The aim of this systematic review was to synthesise qualitative evidence on guideline implementation strategies to improve obstetric care practice in LMIC in order to identify barriers and enablers to their successful implementation.

Methods

We searched MEDLINE and CINAHL databases for articles reporting research findings on barriers and enablers to guideline implementation strategies in obstetric care practice in LMIC. We conducted a “best fit” framework synthesis of the included studies. We used an organisational “stages of change” model as our a priori framework for the synthesis.

Results

Nine studies were included: all were based in Sub-Saharan Africa and in hospital health care facilities. The majority of studies (seven) evaluated one particular guideline implementation strategy: clinical audit and feedback (both criterion-based audit and maternal death reviews), and a minority (two) evaluated educational interventions. A range of barriers and enablers to successful guideline implementation was identified. A key finding of the framework synthesis was that “high” and “low” intrinsic health care professional motivation are overall enablers and barriers, respectively, of successful guideline implementation. We developed a modified “stages of change” model to take account of these findings.

Conclusion

We have identified a number of quality improvement processes that are amenable to change at limited or no additional cost, although some identified barriers may be difficult to address without increased resources. We note the pathways to implementation may be complex and require further research to develop our understanding of individual and organisational behaviours and motivation in LMIC settings.

Trial registration

Appendix
Available only for authorised users
Literature
1.
go back to reference World Health Organisation (WHO). The World Bank. Trends in maternal mortality: 1990-2013. Geneva: WHO; 2014. World Health Organisation (WHO). The World Bank. Trends in maternal mortality: 1990-2013. Geneva: WHO; 2014.
2.
go back to reference Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay CR, Vale L, et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess. 2004;8:iii–iv.CrossRefPubMed Grimshaw JM, Thomas RE, MacLennan G, Fraser C, Ramsay CR, Vale L, et al. Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess. 2004;8:iii–iv.CrossRefPubMed
3.
go back to reference Althabe F, Bergel E, Cafferata ML, Gibbons L, Ciapponi A, Aleman A, et al. Strategies for improving the quality of health care in maternal and child health in low- and middle-income countries: an overview of systematic reviews. Paediatr Perinat Epidemiol. 2008;22 Suppl 1:42–60.CrossRefPubMed Althabe F, Bergel E, Cafferata ML, Gibbons L, Ciapponi A, Aleman A, et al. Strategies for improving the quality of health care in maternal and child health in low- and middle-income countries: an overview of systematic reviews. Paediatr Perinat Epidemiol. 2008;22 Suppl 1:42–60.CrossRefPubMed
4.
go back to reference Dumont A, Fournier P, Abrahamowicz M, Traore M, Haddad S, Fraser WD. Quality of care, risk management, and technology in obstetrics to reduce hospital-based maternal mortality in Senegal and Mali (QUARITE): a cluster-randomised trial. Lancet. 2013;382:146–57.CrossRefPubMed Dumont A, Fournier P, Abrahamowicz M, Traore M, Haddad S, Fraser WD. Quality of care, risk management, and technology in obstetrics to reduce hospital-based maternal mortality in Senegal and Mali (QUARITE): a cluster-randomised trial. Lancet. 2013;382:146–57.CrossRefPubMed
5.
go back to reference Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, et al. Tailored interventions to address determinants of practice. Cochrane Database Syst Rev. 2015;4:CD005470. Baker R, Camosso-Stefinovic J, Gillies C, Shaw EJ, Cheater F, Flottorp S, et al. Tailored interventions to address determinants of practice. Cochrane Database Syst Rev. 2015;4:CD005470.
6.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:a1655.CrossRefPubMedPubMedCentral Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:a1655.CrossRefPubMedPubMedCentral
7.
go back to reference Glenton C, Colvin CJ, Carlsen B, Swartz A, Lewin S, Noyes J, et al. Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis. Cochrane Database Syst Rev. 2013;10:CD010414. Glenton C, Colvin CJ, Carlsen B, Swartz A, Lewin S, Noyes J, et al. Barriers and facilitators to the implementation of lay health worker programmes to improve access to maternal and child health: qualitative evidence synthesis. Cochrane Database Syst Rev. 2013;10:CD010414.
8.
go back to reference Booth A, Carroll C. How to build up the actionable knowledge base: the role of ‘best fit’ framework synthesis for studies of improvement in healthcare. BMJ Quality Safety. 2015;24:700–8.CrossRefPubMedPubMedCentral Booth A, Carroll C. How to build up the actionable knowledge base: the role of ‘best fit’ framework synthesis for studies of improvement in healthcare. BMJ Quality Safety. 2015;24:700–8.CrossRefPubMedPubMedCentral
9.
go back to reference Colvin CJ, de Heer J, Winterton L, Mellenkamp M, Glenton C, Noyes J, et al. A systematic review of qualitative evidence on barriers and facilitators to the implementation of task-shifting in midwifery services. Midwifery. 2013;29:1211–21.CrossRefPubMed Colvin CJ, de Heer J, Winterton L, Mellenkamp M, Glenton C, Noyes J, et al. A systematic review of qualitative evidence on barriers and facilitators to the implementation of task-shifting in midwifery services. Midwifery. 2013;29:1211–21.CrossRefPubMed
10.
go back to reference Imamura MK, Penfold S, Stokes T. Camosso-Stefinovic, J. Shaw, EJ. Hussein, J. A systematic review of implementation strategies to deliver guidelines on obstetric care practice in low- and middle-income countries. Int J Gynaecol Obstet. 2016; in press: Imamura MK, Penfold S, Stokes T. Camosso-Stefinovic, J. Shaw, EJ. Hussein, J. A systematic review of implementation strategies to deliver guidelines on obstetric care practice in low- and middle-income countries. Int J Gynaecol Obstet. 2016; in press:
11.
go back to reference Carroll C, Booth A, Cooper K. A worked example of “best fit” framework synthesis: a systematic review of views concerning the taking of some potential chemopreventive agents. BMC Med Res Methodol. 2011;11:29.CrossRefPubMedPubMedCentral Carroll C, Booth A, Cooper K. A worked example of “best fit” framework synthesis: a systematic review of views concerning the taking of some potential chemopreventive agents. BMC Med Res Methodol. 2011;11:29.CrossRefPubMedPubMedCentral
13.
go back to reference Snilstveit S, Oliver S, Vojtkova M. Narrative approaches to systematic review and synthesis of evidence for international development policy and practice. J Dev Eff. 2012;4:409–29. Snilstveit S, Oliver S, Vojtkova M. Narrative approaches to systematic review and synthesis of evidence for international development policy and practice. J Dev Eff. 2012;4:409–29.
14.
go back to reference The Supporting the Use of Research Evidence (SURE) Collaboration. SURE guides for preparing and using evidence-based policy briefs: 5. Identifying and addressing barriers to implementing policy options. 2011. Available from: www.who.int/evidence/sure/guides. Accessed 18 Oct 2016. The Supporting the Use of Research Evidence (SURE) Collaboration. SURE guides for preparing and using evidence-based policy briefs: 5. Identifying and addressing barriers to implementing policy options. 2011. Available from: www.​who.​int/​evidence/​sure/​guides. Accessed 18 Oct 2016.
15.
go back to reference Belizan M, Bergh AM, Cilliers C, Pattinson RC, Voce A, Group. S, et al. Stages of change: a qualitative study on the implementation of a perinatal audit programme in South Africa. BMC Health Serv Res. 2011;11:243.CrossRefPubMedPubMedCentral Belizan M, Bergh AM, Cilliers C, Pattinson RC, Voce A, Group. S, et al. Stages of change: a qualitative study on the implementation of a perinatal audit programme in South Africa. BMC Health Serv Res. 2011;11:243.CrossRefPubMedPubMedCentral
16.
go back to reference Wilczynski NL, Marks S, Haynes RB. Search strategies for identifying qualitative studies in CINAHL. Qual Health Res. 2007;17:705–10.CrossRefPubMed Wilczynski NL, Marks S, Haynes RB. Search strategies for identifying qualitative studies in CINAHL. Qual Health Res. 2007;17:705–10.CrossRefPubMed
17.
go back to reference Wong SS, Wilczynski NL, Haynes RB. Developing optimal search strategies for detecting clinically relevant qualitative studies in MEDLINE. Stud Health Technol Inform. 2004;107:311–6.PubMed Wong SS, Wilczynski NL, Haynes RB. Developing optimal search strategies for detecting clinically relevant qualitative studies in MEDLINE. Stud Health Technol Inform. 2004;107:311–6.PubMed
18.
go back to reference World Health Organisation (WHO). Kangaroo mother care: a practical guide. Geneva: WHO; 2003. World Health Organisation (WHO). Kangaroo mother care: a practical guide. Geneva: WHO; 2003.
19.
go back to reference Bergh AM, Arsalo I, Malan AF, Patrick M, Pattinson RC, Phillips N. Measuring implementation progress in kangaroo mother care. Acta Paediatr. 2005;94:1102–8.CrossRefPubMed Bergh AM, Arsalo I, Malan AF, Patrick M, Pattinson RC, Phillips N. Measuring implementation progress in kangaroo mother care. Acta Paediatr. 2005;94:1102–8.CrossRefPubMed
20.
go back to reference Belizan M, Meier A, Althabe F, Codazzi A, Colomar M, Buekens P, et al. Facilitators and barriers to adoption of evidence-based perinatal care in Latin American hospitals: a qualitative study. Health Educ Res. 2007;22:839–53.CrossRefPubMed Belizan M, Meier A, Althabe F, Codazzi A, Colomar M, Buekens P, et al. Facilitators and barriers to adoption of evidence-based perinatal care in Latin American hospitals: a qualitative study. Health Educ Res. 2007;22:839–53.CrossRefPubMed
21.
go back to reference Dumont A, Fournier P, Fraser W, Haddad S, Traore M, Diop I, et al. QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali. Trials. 2009;10:85.CrossRefPubMedPubMedCentral Dumont A, Fournier P, Fraser W, Haddad S, Traore M, Diop I, et al. QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali. Trials. 2009;10:85.CrossRefPubMedPubMedCentral
22.
go back to reference Okello DR, Gilson L. Exploring the influence of trust relationships on motivation in the health sector: a systematic review. Hum Resour Health. 2015;13:16.CrossRefPubMedPubMedCentral Okello DR, Gilson L. Exploring the influence of trust relationships on motivation in the health sector: a systematic review. Hum Resour Health. 2015;13:16.CrossRefPubMedPubMedCentral
23.
go back to reference Hannes K, Booth A, Harris J, Noyes J. Celebrating methodological challenges and changes: reflecting on the emergence and importance of the role of qualitative evidence in Cochrane reviews. Syst Rev. 2013;2:84.CrossRefPubMedPubMedCentral Hannes K, Booth A, Harris J, Noyes J. Celebrating methodological challenges and changes: reflecting on the emergence and importance of the role of qualitative evidence in Cochrane reviews. Syst Rev. 2013;2:84.CrossRefPubMedPubMedCentral
24.
go back to reference Dumont A, Tourigny C, Fournier P, Dumont A, Tourigny C, Fournier P. Improving obstetric care in low-resource settings: implementation of facility-based maternal death reviews in five pilot hospitals in Senegal. Hum Resour Health. 2009;7:61.CrossRefPubMedPubMedCentral Dumont A, Tourigny C, Fournier P, Dumont A, Tourigny C, Fournier P. Improving obstetric care in low-resource settings: implementation of facility-based maternal death reviews in five pilot hospitals in Senegal. Hum Resour Health. 2009;7:61.CrossRefPubMedPubMedCentral
25.
go back to reference Glenton C, Lewin S, Scheel IB. Still too little qualitative research to shed light on results from reviews of effectiveness trials: a case study of a Cochrane review on the use of lay health workers. Implement Sci. 2011;6:53.CrossRefPubMedPubMedCentral Glenton C, Lewin S, Scheel IB. Still too little qualitative research to shed light on results from reviews of effectiveness trials: a case study of a Cochrane review on the use of lay health workers. Implement Sci. 2011;6:53.CrossRefPubMedPubMedCentral
26.
go back to reference Hardre PL. Beyond two decades of motivation: a review of the research and practice in instructional design and human performance technology. Hum Resour Dev Rev. 2003;2:54–81.CrossRef Hardre PL. Beyond two decades of motivation: a review of the research and practice in instructional design and human performance technology. Hum Resour Dev Rev. 2003;2:54–81.CrossRef
27.
go back to reference Willis-Shattuck M, Bidwell P, Thomas S, Wyness L, Blaauw D, Ditlopo P. Motivation and retention of health workers in developing countries: a systematic review. BMC Health Serv Res. 2008;8:247.CrossRefPubMedPubMedCentral Willis-Shattuck M, Bidwell P, Thomas S, Wyness L, Blaauw D, Ditlopo P. Motivation and retention of health workers in developing countries: a systematic review. BMC Health Serv Res. 2008;8:247.CrossRefPubMedPubMedCentral
28.
go back to reference Kok MC, Kane SS, Tulloch O, Ormel H, Theobald S, Dieleman M, et al. How does context influence performance of community health workers in low- and middle-income countries? Evidence from the literature. Health Res Policy Syst/BioMed Central. 2015;13:13.CrossRef Kok MC, Kane SS, Tulloch O, Ormel H, Theobald S, Dieleman M, et al. How does context influence performance of community health workers in low- and middle-income countries? Evidence from the literature. Health Res Policy Syst/BioMed Central. 2015;13:13.CrossRef
29.
go back to reference Combs Thorsen V, Sundby J, Meguid T, Malata A. Easier said than done!: methodological challenges with conducting maternal death review research in Malawi. BMC Med Res Methodol. 2014;14:29.CrossRefPubMedPubMedCentral Combs Thorsen V, Sundby J, Meguid T, Malata A. Easier said than done!: methodological challenges with conducting maternal death review research in Malawi. BMC Med Res Methodol. 2014;14:29.CrossRefPubMedPubMedCentral
30.
go back to reference Armstrong CE, Lange IL, Magoma M, Ferla C, Filippi V, Ronsmans C. Strengths and weaknesses in the implementation of maternal and perinatal death reviews in Tanzania: perceptions, processes and practice. Tropical Med Int Health. 2014;19:1087–95.CrossRef Armstrong CE, Lange IL, Magoma M, Ferla C, Filippi V, Ronsmans C. Strengths and weaknesses in the implementation of maternal and perinatal death reviews in Tanzania: perceptions, processes and practice. Tropical Med Int Health. 2014;19:1087–95.CrossRef
31.
go back to reference Braddick L, Tuckey V, Abbas Z, Lissauer D, Ismail K, Manaseki-Holland S, et al. A mixed-methods study of barriers and facilitators to the implementation of postpartum hemorrhage guidelines in Uganda. Int J Gynaecol Obstet. 2016;132:89–93.CrossRefPubMed Braddick L, Tuckey V, Abbas Z, Lissauer D, Ismail K, Manaseki-Holland S, et al. A mixed-methods study of barriers and facilitators to the implementation of postpartum hemorrhage guidelines in Uganda. Int J Gynaecol Obstet. 2016;132:89–93.CrossRefPubMed
32.
go back to reference Ferlie EB, Shortell SM. Improving the quality of health care in the United Kingdom and the United States: a framework for change. Milbank Q. 2001;79:281–315.CrossRefPubMedPubMedCentral Ferlie EB, Shortell SM. Improving the quality of health care in the United Kingdom and the United States: a framework for change. Milbank Q. 2001;79:281–315.CrossRefPubMedPubMedCentral
33.
go back to reference Iwelunmor J, Blackstone S, Veira D, Nwaozuru U, Airhihenbuwa C, Munodawafa D, et al. Toward the sustainability of health interventions implemented in sub-Saharan Africa: a systematic review and conceptual framework. Implement Sci. 2016;11:43.CrossRefPubMedPubMedCentral Iwelunmor J, Blackstone S, Veira D, Nwaozuru U, Airhihenbuwa C, Munodawafa D, et al. Toward the sustainability of health interventions implemented in sub-Saharan Africa: a systematic review and conceptual framework. Implement Sci. 2016;11:43.CrossRefPubMedPubMedCentral
34.
go back to reference Daniels K, Loewenson R, George A, Howard N, Koleva G, Lewin S, et al. Fair publication of qualitative research in health systems: a call by health policy and systems researchers. Int J Equity Health. 2016;15:98.CrossRefPubMedPubMedCentral Daniels K, Loewenson R, George A, Howard N, Koleva G, Lewin S, et al. Fair publication of qualitative research in health systems: a call by health policy and systems researchers. Int J Equity Health. 2016;15:98.CrossRefPubMedPubMedCentral
35.
go back to reference Ameh C, Adegoke A, Hofman J, Ismail FM, Ahmed FM, van den Broek N, et al. The impact of emergency obstetric care training in Somaliland, Somalia. Int J Gynaecol Obstet. 2012;117:283–7.CrossRefPubMed Ameh C, Adegoke A, Hofman J, Ismail FM, Ahmed FM, van den Broek N, et al. The impact of emergency obstetric care training in Somaliland, Somalia. Int J Gynaecol Obstet. 2012;117:283–7.CrossRefPubMed
36.
go back to reference World Health Organisation (WHO). Beyond the numbers: reviewing maternal deaths and complications to make pregnancy safer. Geneva: WHO; 2004. World Health Organisation (WHO). Beyond the numbers: reviewing maternal deaths and complications to make pregnancy safer. Geneva: WHO; 2004.
37.
go back to reference Maaloe N, Sorensen BL, Onesmo R, Secher NJ, Bygbjerg IC, Maaloe N, et al. Prolonged labour as indication for emergency caesarean section: a quality assurance analysis by criterion-based audit at two Tanzanian rural hospitals. BJOG. 2012;119:605–13.CrossRefPubMed Maaloe N, Sorensen BL, Onesmo R, Secher NJ, Bygbjerg IC, Maaloe N, et al. Prolonged labour as indication for emergency caesarean section: a quality assurance analysis by criterion-based audit at two Tanzanian rural hospitals. BJOG. 2012;119:605–13.CrossRefPubMed
38.
go back to reference Nyamtema AS, Urassa DP, Pembe AB, Kisanga F, van Roosmalen J, et al. Factors for change in maternal and perinatal audit systems in Dar es Salaam hospitals, Tanzania. BMC Pregnancy Childbirth. 2010;10:29.CrossRefPubMedPubMedCentral Nyamtema AS, Urassa DP, Pembe AB, Kisanga F, van Roosmalen J, et al. Factors for change in maternal and perinatal audit systems in Dar es Salaam hospitals, Tanzania. BMC Pregnancy Childbirth. 2010;10:29.CrossRefPubMedPubMedCentral
39.
go back to reference Richard F, Ouedraogo C, Zongo V, Ouattara F, Zongo S, Gruenais ME, et al. The difficulty of questioning clinical practice: experience of facility-based case reviews in Ouagadougou, Burkina Faso. BJOG. 2009;116:38–44.CrossRefPubMed Richard F, Ouedraogo C, Zongo V, Ouattara F, Zongo S, Gruenais ME, et al. The difficulty of questioning clinical practice: experience of facility-based case reviews in Ouagadougou, Burkina Faso. BJOG. 2009;116:38–44.CrossRefPubMed
40.
go back to reference Smith H, Brown H, Hofmeyr GJ, Garner P, Smith H, Brown H, et al. Evidence-based obstetric care in South Africa—influencing practice through the ‘Better Births Initiative’. S Afr Med J. 2004;94:117–20.PubMed Smith H, Brown H, Hofmeyr GJ, Garner P, Smith H, Brown H, et al. Evidence-based obstetric care in South Africa—influencing practice through the ‘Better Births Initiative’. S Afr Med J. 2004;94:117–20.PubMed
41.
go back to reference Smith H, Brown H, Hofmeyr J, Dickson-Tetteh K, Garner P, Rees H. Better births initiative: making childbirth better. Johannesburg: Reproductive Health Research Unit, Department of Obstetrics and Gynaecology Chris Hani Baragwanath Hospital; 2001. Smith H, Brown H, Hofmeyr J, Dickson-Tetteh K, Garner P, Rees H. Better births initiative: making childbirth better. Johannesburg: Reproductive Health Research Unit, Department of Obstetrics and Gynaecology Chris Hani Baragwanath Hospital; 2001.
42.
go back to reference van Hamersveld KT, den Bakker E, Nyamtema AS, van den Akker T, Mfinanga EH, van Elteren M, et al. Barriers to conducting effective obstetric audit in Ifakara: a qualitative assessment in an under-resourced setting in Tanzania. Tropical Med Int Health. 2012;17:652–7.CrossRef van Hamersveld KT, den Bakker E, Nyamtema AS, van den Akker T, Mfinanga EH, van Elteren M, et al. Barriers to conducting effective obstetric audit in Ifakara: a qualitative assessment in an under-resourced setting in Tanzania. Tropical Med Int Health. 2012;17:652–7.CrossRef
43.
go back to reference Hutchinson C, Lange I, Kanhonou L, Filippi V, Borchert M, Hutchinson C, et al. Exploring the sustainability of obstetric near-miss case reviews: a qualitative study in the South of Benin. Midwifery. 2010;26:537–43.CrossRefPubMed Hutchinson C, Lange I, Kanhonou L, Filippi V, Borchert M, Hutchinson C, et al. Exploring the sustainability of obstetric near-miss case reviews: a qualitative study in the South of Benin. Midwifery. 2010;26:537–43.CrossRefPubMed
Metadata
Title
Barriers and enablers to guideline implementation strategies to improve obstetric care practice in low- and middle-income countries: a systematic review of qualitative evidence
Authors
Tim Stokes
Elizabeth J. Shaw
Janette Camosso-Stefinovic
Mari Imamura
Lovney Kanguru
Julia Hussein
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Implementation Science / Issue 1/2015
Electronic ISSN: 1748-5908
DOI
https://doi.org/10.1186/s13012-016-0508-1

Other articles of this Issue 1/2015

Implementation Science 1/2015 Go to the issue