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Published in: International Breastfeeding Journal 1/2019

Open Access 01-12-2019 | Research

Donated human milk use and subsequent feeding pattern in neonatal units

Authors: Wesam Alyahya, Debbie Barnett, Andrew Cooper, Ada L. Garcia, Christine A. Edwards, David Young, Judith H. Simpson

Published in: International Breastfeeding Journal | Issue 1/2019

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Abstract

Background

Donated human milk (DHM) is a safe alternative in the absence of mother’s own milk (MOM); however, specific clinical indications for DHM use and its impact on subsequent feeding practice remain unclear. We aimed to audit local DHM use and explore the impact of the introduction of DHM as the first enteral feed on subsequent MOM availability.

Methods

We retrospectively audited DHM recipients nursed in Royal Hospital for Children, Glasgow from 2014 to 2016 against local guidelines. Data were collected from an operational electronic database. Descriptive data analysis was performed to describe DHM use. To explore the association between the first human milk feed with subsequent MOM availability Kruskal Wallis test was used. Adjustments for confounding variables were performed using analysis of variance (ANOVA).

Results

A total of 165 recipients of DHM (5.3% of all admission to RHC) were identified. The majority of recipients (69%) were born < 32 weeks of gestation. The main indication for DHM was prematurity, other indications included congenital anomalies of bowel and heart. The local guideline was adhered to in 87% of cases. The median interquartile range (IQR) at DHM introduction was 6 days (3, 17) and the duration of use was 12 days (6, 22). In those born < 32 weeks of gestation the type of human milk (DHM and/ or MOM) used as first feed did not influence the subsequent median IQR days of feeding with any MOM [DHM 40 (9, 51); MOM 28 (17, 49), MOM & DHM 17 (10, 26) p value = 0.465] after adjusting for birthweight and length of hospital stay.

Conclusions

In our unit, DHM is mainly used in preterm neonates in accordance with existing local guidance. Using DHM as first milk feed did not affect subsequent MOM availability.
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Literature
2.
go back to reference Eidelman AL, Schanler RJ, Johnston M. Section on breastfeeding. Breastfeeding and the use of human milk. Pediatrics. 2012;129:e827–41.CrossRef Eidelman AL, Schanler RJ, Johnston M. Section on breastfeeding. Breastfeeding and the use of human milk. Pediatrics. 2012;129:e827–41.CrossRef
3.
go back to reference Arslanoglu S, Corpeleijn W, Moro G, Braegger C, Campoy C, Colomb V, et al. Donor human milk for preterm infants: current evidence and research directions. J Pediatr Gastroenterol Nutr. 2013;57(4):535–42.CrossRef Arslanoglu S, Corpeleijn W, Moro G, Braegger C, Campoy C, Colomb V, et al. Donor human milk for preterm infants: current evidence and research directions. J Pediatr Gastroenterol Nutr. 2013;57(4):535–42.CrossRef
4.
go back to reference Cooper AR, Barnett D, Gentles E, Cairns L, Simpson JH. Macronutrient content of donor human breast milk. Arch Dis Child Fetal Neonatal Ed. 2013;98(6):F539–41.CrossRef Cooper AR, Barnett D, Gentles E, Cairns L, Simpson JH. Macronutrient content of donor human breast milk. Arch Dis Child Fetal Neonatal Ed. 2013;98(6):F539–41.CrossRef
5.
go back to reference Wojcik KY, Rechtman DT, Lee ML, Montoya A, Medo ET. Macronutrient analysis of a nationwide sample of donor breast milk. J Am Diet Assoc. 2009;109(1):137–40.CrossRef Wojcik KY, Rechtman DT, Lee ML, Montoya A, Medo ET. Macronutrient analysis of a nationwide sample of donor breast milk. J Am Diet Assoc. 2009;109(1):137–40.CrossRef
6.
go back to reference Wardle SP, Hughes A, Chen S, Shaw NJ. Randomised controlled trial of oral vitamin a supplementation in preterm infants to prevent chronic lung disease. Arch Dis Child Fetal Neonatal Ed. 2001;84(1):F9–F13.CrossRef Wardle SP, Hughes A, Chen S, Shaw NJ. Randomised controlled trial of oral vitamin a supplementation in preterm infants to prevent chronic lung disease. Arch Dis Child Fetal Neonatal Ed. 2001;84(1):F9–F13.CrossRef
7.
go back to reference Valentine CJ, Morrow G, Fernandez S, Gulati P, Bartholomew D, Long D. Docosahexaenoic acid and amino acid contents in pasteurized donor milk are low for preterm infants. J Pediatr. 2010;157(6):906–10.CrossRef Valentine CJ, Morrow G, Fernandez S, Gulati P, Bartholomew D, Long D. Docosahexaenoic acid and amino acid contents in pasteurized donor milk are low for preterm infants. J Pediatr. 2010;157(6):906–10.CrossRef
8.
go back to reference Ewaschuk JB, Unger S, O'Connor DL, Stone D, Harvey S, Clandinin MT, et al. Effect of pasteurization on selected immune components of donated human breast milk. J Perinatol. 2011;31(9):593–8.CrossRef Ewaschuk JB, Unger S, O'Connor DL, Stone D, Harvey S, Clandinin MT, et al. Effect of pasteurization on selected immune components of donated human breast milk. J Perinatol. 2011;31(9):593–8.CrossRef
9.
go back to reference Cristofalo EA, Schanler RJ, Blanco CL, Sullivan S, Trawoeger R, Kiechl-Kohlendorfer U. Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants. J Pediatr. 2013;163(6):1592–5.CrossRef Cristofalo EA, Schanler RJ, Blanco CL, Sullivan S, Trawoeger R, Kiechl-Kohlendorfer U. Randomized trial of exclusive human milk versus preterm formula diets in extremely premature infants. J Pediatr. 2013;163(6):1592–5.CrossRef
10.
go back to reference Quigley M, Embleton N, McGuire W. Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev. 2018;(7):CD002971. Quigley M, Embleton N, McGuire W. Formula versus donor breast milk for feeding preterm or low birth weight infants. Cochrane Database Syst Rev. 2018;(7):CD002971.
11.
go back to reference Henry MC, Moss RL. Neonatal necrotizing enterocolitis. Semin Pediatr Surg. 2008;17(2):98–109.CrossRef Henry MC, Moss RL. Neonatal necrotizing enterocolitis. Semin Pediatr Surg. 2008;17(2):98–109.CrossRef
12.
go back to reference Rees CM, Pierro A, Eaton S. Neurodevelopmental outcomes of neonates with medically and surgically treated necrotizing enterocolitis. Arch Dis Child Fetal Neonatal Ed. 2007;92(3):F193–8.CrossRef Rees CM, Pierro A, Eaton S. Neurodevelopmental outcomes of neonates with medically and surgically treated necrotizing enterocolitis. Arch Dis Child Fetal Neonatal Ed. 2007;92(3):F193–8.CrossRef
13.
go back to reference Pike K, Brocklehurst P, Jones D, Kenyon S, Salt A, Taylor D, et al. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: the ORACLE children study. Arch Dis Child Fetal Neonatal Ed. 2012;97(5):F318–22.CrossRef Pike K, Brocklehurst P, Jones D, Kenyon S, Salt A, Taylor D, et al. Outcomes at 7 years for babies who developed neonatal necrotising enterocolitis: the ORACLE children study. Arch Dis Child Fetal Neonatal Ed. 2012;97(5):F318–22.CrossRef
15.
go back to reference Williams T, Nair H, Simpson J, Embleton N. Use of donor human milk and maternal breastfeeding rates: a systematic review. J Hum Lact. 2016;32(2):212–20.CrossRef Williams T, Nair H, Simpson J, Embleton N. Use of donor human milk and maternal breastfeeding rates: a systematic review. J Hum Lact. 2016;32(2):212–20.CrossRef
17.
go back to reference Menon G, Williams TC. Human milk for preterm infants: why, what, when and how? Arch Dis Child Fetal Neonatal Ed. 2013;98(6):F559–62.CrossRef Menon G, Williams TC. Human milk for preterm infants: why, what, when and how? Arch Dis Child Fetal Neonatal Ed. 2013;98(6):F559–62.CrossRef
18.
go back to reference Parker MG, Barrero-Castillero A, Corwin BK, Kavanagh PL, Belfort MB, Wang CJ. Pasteurized human donor milk use among US level 3 neonatal intensive care units. J Hum Lact. 2013;29(3):381–9.CrossRef Parker MG, Barrero-Castillero A, Corwin BK, Kavanagh PL, Belfort MB, Wang CJ. Pasteurized human donor milk use among US level 3 neonatal intensive care units. J Hum Lact. 2013;29(3):381–9.CrossRef
19.
go back to reference Power BD, O’Dea MI, O’Grady MJ. Donor human milk use in neonatal units: practice and opinions in the Republic of Ireland. Ir J Med Sci. 2018;188(2):601–5.CrossRef Power BD, O’Dea MI, O’Grady MJ. Donor human milk use in neonatal units: practice and opinions in the Republic of Ireland. Ir J Med Sci. 2018;188(2):601–5.CrossRef
20.
go back to reference Weaver G. Under the spotlight: queen Charlotte’s hospital milk bank at 75. Midirs Midwifery Digest. 2015;25(4):494. Weaver G. Under the spotlight: queen Charlotte’s hospital milk bank at 75. Midirs Midwifery Digest. 2015;25(4):494.
21.
go back to reference Battersby C, Mousinho RM, Marciano Alves M, Longford N, Modi N. UK Neonatal Collaborative Necrotising (UKNC-NEC) Study Group. Use of pasteurised human donor milk across neonatal networks in England. Early Hum Dev. 2018;118:32–6.CrossRef Battersby C, Mousinho RM, Marciano Alves M, Longford N, Modi N. UK Neonatal Collaborative Necrotising (UKNC-NEC) Study Group. Use of pasteurised human donor milk across neonatal networks in England. Early Hum Dev. 2018;118:32–6.CrossRef
22.
go back to reference Parker MG, Burnham L, Mao W, Philipp BL, Merewood A. Implementation of a donor milk program is associated with greater consumption of mothers’ own milk among VLBW infants in a US, level 3 NICU. J Hum Lact. 2016;32(2):221–8.CrossRef Parker MG, Burnham L, Mao W, Philipp BL, Merewood A. Implementation of a donor milk program is associated with greater consumption of mothers’ own milk among VLBW infants in a US, level 3 NICU. J Hum Lact. 2016;32(2):221–8.CrossRef
23.
go back to reference Kantorowska A, Wei JC, Cohen RS, Lawrence RA, Gould JB, Lee HC. Impact of donor milk availability on breast milk use and necrotizing enterocolitis rates. Pediatrics. 2016;137(3):e20153123.CrossRef Kantorowska A, Wei JC, Cohen RS, Lawrence RA, Gould JB, Lee HC. Impact of donor milk availability on breast milk use and necrotizing enterocolitis rates. Pediatrics. 2016;137(3):e20153123.CrossRef
24.
go back to reference Torres MI, López CM, Román SV, Díaz CA, Cruz-Rojo J, Cooke EF, et al. Does opening a milk bank in a neonatal unit change infant feeding practices? A before and after study. Int Breastfeed J. 2010;5:4.CrossRef Torres MI, López CM, Román SV, Díaz CA, Cruz-Rojo J, Cooke EF, et al. Does opening a milk bank in a neonatal unit change infant feeding practices? A before and after study. Int Breastfeed J. 2010;5:4.CrossRef
25.
go back to reference Ehrenkranz RA, Das A, Wrage LA, Poindexter BB, Higgins RD, Stoll BJ, et al. Early nutrition mediates the influence of severity of illness on extremely LBW infants. Pediatr Res. 2011;69(6):522.CrossRef Ehrenkranz RA, Das A, Wrage LA, Poindexter BB, Higgins RD, Stoll BJ, et al. Early nutrition mediates the influence of severity of illness on extremely LBW infants. Pediatr Res. 2011;69(6):522.CrossRef
26.
go back to reference Belfort MB, Drouin K, Riley JF, Gregory KE, Philipp BL, Parker MG, et al. Prevalence and trends in donor milk use in the well-baby nursery: a survey of Northeast United States birth hospitals. Breastfeed Med. 2018;13(1):34–41.CrossRef Belfort MB, Drouin K, Riley JF, Gregory KE, Philipp BL, Parker MG, et al. Prevalence and trends in donor milk use in the well-baby nursery: a survey of Northeast United States birth hospitals. Breastfeed Med. 2018;13(1):34–41.CrossRef
27.
go back to reference Kair LR, Flaherman VJ, Colaizy TT. Effect of donor milk supplementation on breastfeeding outcomes in term newborns: a randomized controlled trial. Clin Pediatr. 2019;58(5):534–40.CrossRef Kair LR, Flaherman VJ, Colaizy TT. Effect of donor milk supplementation on breastfeeding outcomes in term newborns: a randomized controlled trial. Clin Pediatr. 2019;58(5):534–40.CrossRef
Metadata
Title
Donated human milk use and subsequent feeding pattern in neonatal units
Authors
Wesam Alyahya
Debbie Barnett
Andrew Cooper
Ada L. Garcia
Christine A. Edwards
David Young
Judith H. Simpson
Publication date
01-12-2019
Publisher
BioMed Central
Published in
International Breastfeeding Journal / Issue 1/2019
Electronic ISSN: 1746-4358
DOI
https://doi.org/10.1186/s13006-019-0233-x

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