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Published in: Diagnostic Pathology 1/2021

Open Access 01-12-2021 | Malnutrition | Commentary

Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action

Authors: Amira Mohammed Ali, Hiroshi Kunugi

Published in: Diagnostic Pathology | Issue 1/2021

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Abstract

Proteins represent the major building blocks of body tissues, and they regulate signaling involved in most cellular activities. Coronavirus disease 2019 (COVID-19) infection has been associated with high fatality, especially among older adults. The main cause of death is pulmonary tissue damage and multiple organ failure. The disease is associated with a hypercatabolic state that entails excessive protein loss. This review commentary sheds the light on hypoproteinemia in symptomatic/hospitalized COVID-19 with a special emphasis on its pathophysiology, screening, as well as its contribution to disease severity and adverse effects.
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Metadata
Title
Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action
Authors
Amira Mohammed Ali
Hiroshi Kunugi
Publication date
01-12-2021
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2021
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/s13000-021-01092-5

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