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Diagnostic Pathology

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Open Access 01-12-2017 | Case report

Renal cell -like carcinoma of the nasal cavity: a case report and review of the literature

Authors: Zhenwei-Chen, Zhaoming-Wang, Hongqi-Shi, Qinwei-Liu

Published in: Diagnostic Pathology | Issue 1/2017

Abstract

Background

Sinonasal renal cell-like carcinoma (SRCLC) is an extremely rare low malignant tumor arising in the sinonasal tract, with histological mimicry of renal cell carcinoma.

Case presentation

We present a case of sinonasal renal cell-like carcinoma in a 63-year-old male patient. Computer tomography(CT) scanning revealed a soft tissue mass at the left nasal cavity and choana. Histologically, the predominant tumor architecture was follicular to glandular with intervening fibrous septa. The tumor cells were uniform cuboidal to polyhedral with abundant clear or eosinophilic cytoplasm. Immunohistochemically, the tumor cells were strongly positive for CK7, EMA, vimentin, SOX10, S-100, and focally positive for CA9. During 6 months of follow-up, there was no clinical or radiological evidence of recurrence or metastasis.

Conclusion

SRCLC has microscopic features which overlap with tumors that contain clear cells. Thus, several other tumors must be considered in the differential diagnosis of a tumor of the sinonasal region with clear cells, especially metastatic renal clear cell carcinoma. SRCLC is an indolent tumor and none of the reported SRCLC patients had metastatic disease.

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Title: Renal cell -like carcinoma of the nasal cavity: a case report and review of the literature
Authors: Zhenwei-Chen
Zhaoming-Wang
Hongqi-Shi
Qinwei-Liu
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Diagnostic Pathology / Issue 1/2017
Electronic ISSN: 1746-1596
DOI: https://doi.org/10.1186/s13000-017-0660-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Renal cell -like carcinoma of the nasal cavity: a case report and review of the literature

Abstract

Background

Case presentation

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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