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Published in: Annals of General Psychiatry 1/2018

Open Access 01-12-2018 | Primary research

Suicide ideation and attempts among people with epilepsy in Addis Ababa, Ethiopia

Authors: Kelelemua Haile, Tadesse Awoke, Getinet Ayano, Minale Tareke, Andargie Abate, Mulugeta Nega

Published in: Annals of General Psychiatry | Issue 1/2018

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Abstract

Background

Suicidal ideation and attempts are more frequent in people with epilepsy than in general population and suicide attempt increases the chance of later completed suicide. The aim of this study was to assess the prevalence and associated factors of suicidal ideation and attempt among people with epilepsy in Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.

Methods

Institution-based cross-sectional study was conducted from May to June 2014 at Amanuel Mental Specialized Hospital among people with epilepsy. The pre-tested semi-structured questionnaire was used for interviewing the study participants. Logistic regression analysis was used to assess predictors of suicidal ideation and attempt.

Results

The study indicated that the prevalence of suicidal ideation and attempt among people with epilepsy were 29.8 and 14.1%, respectively. Poor social support, drug treatment for mental illness, had co-morbid depression, no seizure free within 1 year and family history committed suicide were significantly associated with suicidal ideation and attempt.

Conclusion

The prevalence of suicidal ideation and attempt in people with epilepsy found to be higher when compared to general population. Therefore, screening all epilepsy patients should be done for early diagnosis and treatment.
Literature
1.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.CrossRef American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.CrossRef
2.
go back to reference Sadock BJ, Sadock VA. Kaplan & Sadock’s synopsis of psychiatry: behavioral sciences/clinical psychiatry. 11th ed. Alphen aan den Rijn: Wolters Kluwer; 2015. Sadock BJ, Sadock VA. Kaplan & Sadock’s synopsis of psychiatry: behavioral sciences/clinical psychiatry. 11th ed. Alphen aan den Rijn: Wolters Kluwer; 2015.
3.
go back to reference World Health Organization. Preventing suicide. A global imperative. Geneva: World Health Organization; 2014. p. 7–12. World Health Organization. Preventing suicide. A global imperative. Geneva: World Health Organization; 2014. p. 7–12.
4.
5.
go back to reference World Health Organization. Epilepsy in the WHO eastern Mediterranean region: bridging the gap. Geneva: World Health Organization; 2010. World Health Organization. Epilepsy in the WHO eastern Mediterranean region: bridging the gap. Geneva: World Health Organization; 2010.
6.
go back to reference Mazza M, Bria P, Mazza S. Depression and suicide in epilepsy: a fact or artifact? J Neurol Sci. 2007;260:300–1.CrossRefPubMed Mazza M, Bria P, Mazza S. Depression and suicide in epilepsy: a fact or artifact? J Neurol Sci. 2007;260:300–1.CrossRefPubMed
7.
go back to reference Alsaadi T, Zamel K, Sameer A, Fathalla W, Koudier I. Depressive disorders in patients with epilepsy: why should neurologists care? Health. 2013;5(6A1):14–20.CrossRef Alsaadi T, Zamel K, Sameer A, Fathalla W, Koudier I. Depressive disorders in patients with epilepsy: why should neurologists care? Health. 2013;5(6A1):14–20.CrossRef
8.
go back to reference Thompson AW, Miller JW, Katon W, Chayto N, Ciechanowski P. Sociodemographic and clinical factors associated with depression in epilepsy. Epilepsy Behav. 2009;14(4):655–60.CrossRefPubMedPubMedCentral Thompson AW, Miller JW, Katon W, Chayto N, Ciechanowski P. Sociodemographic and clinical factors associated with depression in epilepsy. Epilepsy Behav. 2009;14(4):655–60.CrossRefPubMedPubMedCentral
11.
go back to reference Jones JE, Hermann BP, Barry JJ, Gilliam FG, Kanner AM, Meador KJ. Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy. Epilepsy Behav. 2003;4:31–8.CrossRef Jones JE, Hermann BP, Barry JJ, Gilliam FG, Kanner AM, Meador KJ. Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy. Epilepsy Behav. 2003;4:31–8.CrossRef
14.
go back to reference Christensen J, Vestergaard M, Mortensen P, Sidenius P, Agerbo E. Epilepsy and risk of suicide: a population-based case–control study. Lancet Neurol. 2007;6:693–8.CrossRefPubMed Christensen J, Vestergaard M, Mortensen P, Sidenius P, Agerbo E. Epilepsy and risk of suicide: a population-based case–control study. Lancet Neurol. 2007;6:693–8.CrossRefPubMed
15.
go back to reference Kanner AM. Suicidality and epilepsy: a complex relationship that remains misunderstood and underestimated. Curr Rev Clin Sci. 2009;9(3):63–6. Kanner AM. Suicidality and epilepsy: a complex relationship that remains misunderstood and underestimated. Curr Rev Clin Sci. 2009;9(3):63–6.
16.
go back to reference CDC. Suicide rate is 22% higher among people with epilepsy than the general population. Epilepsy Behav. 2016;61:210–7.CrossRef CDC. Suicide rate is 22% higher among people with epilepsy than the general population. Epilepsy Behav. 2016;61:210–7.CrossRef
17.
go back to reference Kessler RC, Üstün TB. The world mental health (WMH) survey initiative version of the world health organization (WHO) composite international diagnostic interview (CIDI). Int J Methods Psychiatr Res. 2004;13(2):93–121.CrossRefPubMed Kessler RC, Üstün TB. The world mental health (WMH) survey initiative version of the world health organization (WHO) composite international diagnostic interview (CIDI). Int J Methods Psychiatr Res. 2004;13(2):93–121.CrossRefPubMed
18.
go back to reference Gelaye B, Williams MA, Lemma S, Deyessa N, Bahretibeb Y, Shibre T, Wondimagegn D, Lemenhe A, Fann JR, Vander Stoep A. Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa. Psychiatry Res. 2013;210(2):653–61.CrossRefPubMed Gelaye B, Williams MA, Lemma S, Deyessa N, Bahretibeb Y, Shibre T, Wondimagegn D, Lemenhe A, Fann JR, Vander Stoep A. Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa. Psychiatry Res. 2013;210(2):653–61.CrossRefPubMed
19.
go back to reference Bitew T, Hanlon C, Kebede E, Honikman S, Fekadu A. Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia. BMC Psychiatry. 2017;17(1):301.CrossRefPubMedPubMedCentral Bitew T, Hanlon C, Kebede E, Honikman S, Fekadu A. Antenatal depressive symptoms and perinatal complications: a prospective study in rural Ethiopia. BMC Psychiatry. 2017;17(1):301.CrossRefPubMedPubMedCentral
20.
go back to reference Meltzer H. Development of a common instrument for mental health. In: Nosikov A, Gudex C, editors. EUROHIS: developing common instruments for health surveys. Amsterdam: IOS Press Google Scholar; 2003. Meltzer H. Development of a common instrument for mental health. In: Nosikov A, Gudex C, editors. EUROHIS: developing common instruments for health surveys. Amsterdam: IOS Press Google Scholar; 2003.
21.
go back to reference Hecimovic H, Santos JM, Carter J, Attarian HP, Fessler AJ, Vahle V, Gilliam F. Depression but not seizure factors or quality of life predicts suicidality in epilepsy. Epilepsy Behav. 2012;24(4):426–9.CrossRefPubMedPubMedCentral Hecimovic H, Santos JM, Carter J, Attarian HP, Fessler AJ, Vahle V, Gilliam F. Depression but not seizure factors or quality of life predicts suicidality in epilepsy. Epilepsy Behav. 2012;24(4):426–9.CrossRefPubMedPubMedCentral
22.
go back to reference Andrijić NL, Alajbegović A, Zec SL, Loga S. Suicidal ideation and thoughts of death in epilepsy patients. Psychiatr Danub. 2014;26(1):52–5.PubMed Andrijić NL, Alajbegović A, Zec SL, Loga S. Suicidal ideation and thoughts of death in epilepsy patients. Psychiatr Danub. 2014;26(1):52–5.PubMed
23.
go back to reference Stefanello S, Marín-Léon L, Fernandes PT, Li LM, Botega NJ. Psychiatric comorbidity and suicidal behavior in epilepsy: a community-based case–control study. Epilepsia. 2010;51(7):1120–5.CrossRefPubMed Stefanello S, Marín-Léon L, Fernandes PT, Li LM, Botega NJ. Psychiatric comorbidity and suicidal behavior in epilepsy: a community-based case–control study. Epilepsia. 2010;51(7):1120–5.CrossRefPubMed
24.
go back to reference Espinosa AG, Machado RA, González SB, González ME, Montoto AP, Sotomayor GT. Wisconsin Card Sorting Test performance and impulsivity in patients with temporal lobe epilepsy: suicidal risk and suicide attempts. Epilepsy Behav. 2010;17:39–45.CrossRef Espinosa AG, Machado RA, González SB, González ME, Montoto AP, Sotomayor GT. Wisconsin Card Sorting Test performance and impulsivity in patients with temporal lobe epilepsy: suicidal risk and suicide attempts. Epilepsy Behav. 2010;17:39–45.CrossRef
25.
go back to reference Buljan R, Šantić AM. Suicide attempts in hospital-treated epilepsy patients. Acta Clin Croat. 2011;50(4):485–9.PubMed Buljan R, Šantić AM. Suicide attempts in hospital-treated epilepsy patients. Acta Clin Croat. 2011;50(4):485–9.PubMed
26.
go back to reference Salgado PCB, Nogueira MH, Yasuda CL, Cendes F. Screening symptoms of depression and suicidal ideation in people with epilepsy using the beck depression inventory. J Epilepsy Clin Neurophysiol. 2012;18(3):85–91.CrossRef Salgado PCB, Nogueira MH, Yasuda CL, Cendes F. Screening symptoms of depression and suicidal ideation in people with epilepsy using the beck depression inventory. J Epilepsy Clin Neurophysiol. 2012;18(3):85–91.CrossRef
27.
go back to reference Seo JG, Lee JJ, Cho YW, Lee SJ, Kim JE, Moon HJ, Park SP. Suicidality and its risk factors in Korean people with epilepsy: a MEPSY study. J Clin Neurol. 2015;11(1):32–41.CrossRefPubMedPubMedCentral Seo JG, Lee JJ, Cho YW, Lee SJ, Kim JE, Moon HJ, Park SP. Suicidality and its risk factors in Korean people with epilepsy: a MEPSY study. J Clin Neurol. 2015;11(1):32–41.CrossRefPubMedPubMedCentral
28.
go back to reference Hara E, Akanuma N, Adachi N, Hara K, Koutroumanidis M. Suicide attempts in adult patients with idiopathic generalized epilepsy. Psychiatry Clin Neurosci. 2009;63:225–9.CrossRefPubMed Hara E, Akanuma N, Adachi N, Hara K, Koutroumanidis M. Suicide attempts in adult patients with idiopathic generalized epilepsy. Psychiatry Clin Neurosci. 2009;63:225–9.CrossRefPubMed
29.
go back to reference Ajdacic-Gross V, Weiss MG, Ring M, Hepp U, Bopp M, Gutzwiller F, Rössler W. Methods of suicide: international suicide patterns derived from the WHO mortality database. Bull World Health Organ. 2008;86(9):726–32.CrossRefPubMedPubMedCentral Ajdacic-Gross V, Weiss MG, Ring M, Hepp U, Bopp M, Gutzwiller F, Rössler W. Methods of suicide: international suicide patterns derived from the WHO mortality database. Bull World Health Organ. 2008;86(9):726–32.CrossRefPubMedPubMedCentral
30.
go back to reference Tegegne MT, Mossie TB, Awoke AA, Assaye AM, Gebrie BT, Eshetu DA. Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia. BMC Psychiatry. 2015;15(210):210.CrossRefPubMedPubMedCentral Tegegne MT, Mossie TB, Awoke AA, Assaye AM, Gebrie BT, Eshetu DA. Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia. BMC Psychiatry. 2015;15(210):210.CrossRefPubMedPubMedCentral
31.
go back to reference Tegegne MT, Awoke AA. Perception of stigma and associated factors in people with epilepsy at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia. Int J Psychiatry Clin Pract. 2016;21(1):58–63. Tegegne MT, Awoke AA. Perception of stigma and associated factors in people with epilepsy at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia. Int J Psychiatry Clin Pract. 2016;21(1):58–63.
32.
go back to reference World Health Organization. Suicide huge but preventable public health problem. Geneva: World Health Organization; 2004. World Health Organization. Suicide huge but preventable public health problem. Geneva: World Health Organization; 2004.
33.
go back to reference Christensen J, Vestergaard M, Mortensen PB, Sidenius P, Agerbo E. Epilepsy and risk of suicide: a population-based case–control study. Lancet Neurol. 2007;6(8):693–8.CrossRefPubMed Christensen J, Vestergaard M, Mortensen PB, Sidenius P, Agerbo E. Epilepsy and risk of suicide: a population-based case–control study. Lancet Neurol. 2007;6(8):693–8.CrossRefPubMed
34.
go back to reference Nilsson L, Ahlbom A, Farahmand BY, Asberg M, Tomson T. Risk factors for suicide in epilepsy: a case control study. Epilepsia. 2002;43(6):644–51.CrossRefPubMed Nilsson L, Ahlbom A, Farahmand BY, Asberg M, Tomson T. Risk factors for suicide in epilepsy: a case control study. Epilepsia. 2002;43(6):644–51.CrossRefPubMed
35.
go back to reference Qin P, Agerbo E, Mortensen PB. Suicide risk in relation to family history of completed suicide and psychiatric disorders: a nested case–control study based on longitudinal registers. Lancet. 2002;360:1126–30.CrossRefPubMed Qin P, Agerbo E, Mortensen PB. Suicide risk in relation to family history of completed suicide and psychiatric disorders: a nested case–control study based on longitudinal registers. Lancet. 2002;360:1126–30.CrossRefPubMed
36.
go back to reference Mainio A, Alamäki K, Karvonen K, Hakko H, Särkioja T, Räsänen P. Depression and suicide in epileptic victims: a population-based study of suicide victims during the years 1988–2002 in northern Finland. Epilepsy Behav. 2007;11:389–93.CrossRefPubMed Mainio A, Alamäki K, Karvonen K, Hakko H, Särkioja T, Räsänen P. Depression and suicide in epileptic victims: a population-based study of suicide victims during the years 1988–2002 in northern Finland. Epilepsy Behav. 2007;11:389–93.CrossRefPubMed
38.
go back to reference Hawton K, i Comabella CC, Haw C, Saunders K. Risk factors for suicide in individuals with depression: a systematic review. J Affect Disord. 2013;147(1):17–28.CrossRefPubMed Hawton K, i Comabella CC, Haw C, Saunders K. Risk factors for suicide in individuals with depression: a systematic review. J Affect Disord. 2013;147(1):17–28.CrossRefPubMed
39.
go back to reference Spina E, Trifirò G, Caputi AP. Pharmacovigilance in psychiatry: an introduction. In: Pharmacovigilance in psychiatry. Springer; 2016. p. 3–7. Spina E, Trifirò G, Caputi AP. Pharmacovigilance in psychiatry: an introduction. In: Pharmacovigilance in psychiatry. Springer; 2016. p. 3–7.
40.
go back to reference Pompili M, Vanacore N, Macone S, Amore M, Perticoni G, Tonna M, Sasso E, Lester D, Innamorati M, Gazzella S, et al. Depression, hopelessness and suicide risk among patients suffering from epilepsy. Ann Ist super sAnItà 2007. 2007;43(4):425–9. Pompili M, Vanacore N, Macone S, Amore M, Perticoni G, Tonna M, Sasso E, Lester D, Innamorati M, Gazzella S, et al. Depression, hopelessness and suicide risk among patients suffering from epilepsy. Ann Ist super sAnItà 2007. 2007;43(4):425–9.
Metadata
Title
Suicide ideation and attempts among people with epilepsy in Addis Ababa, Ethiopia
Authors
Kelelemua Haile
Tadesse Awoke
Getinet Ayano
Minale Tareke
Andargie Abate
Mulugeta Nega
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2018
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/s12991-018-0174-6

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