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BMC Psychiatry
Published in: BMC Psychiatry 1/2015

Open Access 01-12-2015 | Research article

Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia

Authors: Minale Tareke Tegegne, Tilahun Belete Mossie, Andargie Abate Awoke, Ashagre Molla Assaye, Belete Temitm Gebrie, Desalegn Asmare Eshetu

Published in: BMC Psychiatry | Issue 1/2015

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Abstract

Background

Although depression and anxiety disorders are very common in people with epilepsy; there are no studies that assessed the magnitude and associated factors among epileptic people in Ethiopia. Therefore, this study determined prevalence and associated factors of depression and anxiety disorders in people with epilepsy.

Method

An institution based cross-sectional study was conducted from April to May, 2013, among 423 people with epilepsy from the outpatient department of Amanuel Mental Specialized Hospital. Depression and anxiety were assessed using the Hospital Anxiety and Depression Scale. Logistic regression analysis was used to assess predictors of depression and anxiety.

Results

The prevalence of anxiety and depression among epileptic people were 33.5 and 32.8 %, respectively. Monthly income, frequency of seizure and side effects of anti convulsants were found to be significantly associated with both depression and anxiety. Being divorced/widowed was associated with anxiety while using poly-therapy of anti convulsants, perceived stigma, and inability to read or write were associated with depression.

Conclusion

The prevalence of co-morbid anxiety and depression was found to be high among people with epilepsy. Early identification of co-morbid depression and anxiety in people with epilepsy and managing epilepsy to become seizure free should be of great concern for health care providers.
Literature
1.
WHO. Epilepsy in the WHO eastern Mediterranean region: Bridging the gap. 2010.
2.
3.
4.
Kaplan & Sadock. Synopsis of Psychiatry, 2007; 10th edition. 527–528 and 580–582
5.
Sadock BJ, Sadock VA, Ruiz P. Kaplan and Sadock's Comprehensive Textbook of Psychiatry, 9th Edition. 2009. p. 1840–4.
6.
7.
Epilepsy Action Australia. Seizure Smart - a question of risk: life, death and epilepsy. 2011. Available at www.​epilepsy.​org.​au. (accessed on September, 2014)
8.
Ekinci O, Titus J, Rodopman A, Berkem M, Trevathan E. Depression and anxiety in children and adolescents with epilepsy: prevalence, risk factors, and treatment. Epilepsy Behav. 2009;14:8–18.CrossRefPubMed
9.
10.
Phabphal K, Sattawatcharawanich S, Sathirapunya P, Limapichart K. Anxiety and depression in Thai epileptic patients. J Med Assoc Thai. 2007;90(10):2010–5.PubMed
11.
Arora H, Kaur R. Prevalence of depression in epileptic patients. Delhi Psychiatry J. 2009;12(2):231–3.
12.
Stefanello S, Marín-Léon L, Fernandes PT, Li L, Botega NJ. Depression and anxiety in a community sample with epilepsy in Brazil. Arq Neuropsiquiatr. 2011;69(2-B):342–8.CrossRefPubMed
13.
Pedroso de Souza EA, Salgado PB. A psychosocial view of anxiety and depression in epilepsy. Science Direct. Epilepsy Behav. 2006;8:232–8.CrossRef
14.
Kwan P, Yu E, Leung H, Leon T, Mychaskiw MA. Association of subjective anxiety, depression and sleep disturbance with quality of life in adults with epilepsy. Eilepsia. 2009;50(5):1059–66.CrossRef
15.
Yousafzai AR, Yousafzai AW, Taj R. Frequency of depression in epilepsy: a hospital based study. J Ayub Med Coll Abbottabad. 2009;21(2):73–5.PubMed
16.
Hamed SA, Metwaly NH, Hassan MM, Mohamed KA, Ahmed MA, Soliman AA, et al. Depression in adults with epilepsy: Relationship to psychobiological variables. World J Neurol. 2012;2(1):1–10.CrossRef
17.
Marsh L, Rao V. Psychiatric complications in patients with epilepsy: a review. Epilepsy Res. 2002;49:11–33.CrossRefPubMed
18.
Federal Ministry of Health. Health and health related indicators of 2012/2013, Version 2. 2014.
19.
Reda AA. Reliability and validity of the Ethiopian version of the Hospital Anxiety and Depression Scale (HADS) in HIV infected patients. PLoS One. 2011;6(1), e16049.CrossRefPubMedPubMedCentral
20.
Baskind R, Birbeck GL. Epilepsy-associated stigma in sub-Saharan Africa: the social landscape of a disease. Epilepsy Behav. 2005;7:68–73.CrossRefPubMed
21.
Asadi-Pooya AA, Sperling MR. Depression and anxiety in patients with epilepsy, with or without other chronic disorders. Iran Red Crescent Med J. 2011;13(2):112–6.PubMedPubMedCentral
22.
Prina AM, Ferri CP, Guerra M, Brayne C, Prince M. Co-occurrence of anxiety and depression amongst older adults in low- and middle-income countries: findings from the 10/66 study. Psychol Med. 2011;41(10):2047–56.CrossRefPubMed
23.
Lemstra M, Neudorf C, D’Arcy C, Kunst A, Warren LM, Bennett NR. A systematic review of depressed mood and anxiety by SES in youth aged 10–15 years. Can J Public Health. 2008;99:125–9.PubMed
24.
Tsegabrhan H, Negash A, Tesfay K, Abera M. Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia. Neurol India. 2015;62:649–55.
25.
Joseph N, Ray A, Reshma BK, Bhat S, Herady M, Kumar A. Assessment of quality of life, stigma associated and self-management practices among patients suffering from epileptic seizures: a cross sectional study. J Neurosci Behav Health. 2011;3(7):91–8.
Metadata
Title
Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia
Authors
Minale Tareke Tegegne
Tilahun Belete Mossie
Andargie Abate Awoke
Ashagre Molla Assaye
Belete Temitm Gebrie
Desalegn Asmare Eshetu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2015
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-015-0589-4

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