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Annals of General Psychiatry
Published in: Annals of General Psychiatry 1/2016

Open Access 01-12-2016 | Primary research

A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis

Authors: Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin, Dominique Malauzat

Published in: Annals of General Psychiatry | Issue 1/2016

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Abstract

Background

The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clinical outcome and care consumption over the 2 years following the request.

Methods

The visits were conducted at baseline (M0) and at 6, 12, 18 and 24 months (M6, M12, M18, M24). Demographic, clinical and psychometric data [Beck Depression Inventory (BDI), AUDIT questionnaire, Global Assessment of Functioning (GAF) scale], and information regarding the use of psychiatric care and therapeutics were collected.

Results

The 330 subjects included were mostly male, aged 45.2 ± 10.2 years with an employment rate of 55.4 %, living alone (69.1 %), with a psychiatric comorbidity (60.9 %), especially depressive, and with few somatic complications. Their global functioning was poor (GAF score 49.14 ± 15.6), and less than 10 % were addicted to another substance. The abstinence rate at 24 months was 41.4 %, but only 23 % (20) abstained continuously between M0 and M24, and 66.7 % (58) intermittently. The likelihood of abstinence at M24 was greater for females aged over 60 years. The BDI score decreased significantly between M0 and M24. In all, 56.2 % of the participants were re-hospitalized after weaning, but were not integrated in long-term medical care.

Conclusions

Abstinence after alcohol withdrawal fluctuated over time indicating the need for long-term support. The treatment of AUD should not target total, continuous abstinence. Prognostic profiles combining socio-demographic, clinical and biological indicators must be established.
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Metadata
Title
A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis
Authors
Philippe Nubukpo
Murielle Girard
Jean-Marie Sengelen
Sophie Bonnefond
Aurélien Varnoux
Benoît Marin
Dominique Malauzat
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2016
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/s12991-016-0111-5

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