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Open Access 01-12-2021 | Coronavirus | Short report

Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean

Authors: Axel O. G. Hoarau, Steven M. Goodman, Dana Al Halabi, Beza Ramasindrazana, Erwan Lagadec, Gildas Le Minter, Marie Köster, Andréa Dos Santos, M. Corrie Schoeman, Eduardo S. Gudo, Patrick Mavingui, Camille Lebarbenchon

Published in: Virology Journal | Issue 1/2021

Abstract

Co-infections have a key role in virus transmission in wild reservoir hosts. We investigated the simultaneous presence of astroviruses, coronaviruses, and paramyxoviruses in bats from Madagascar, Mayotte, Mozambique, and Reunion Island. A total of 871 samples from 28 bat species representing 8 families were tested by polymerase chain reactions (PCRs) targeting the RNA-dependent RNA-polymerase genes. Overall, 2.4% of bats tested positive for the presence of at least two viruses, only on Madagascar and in Mozambique. Significant variation in the proportion of co-infections was detected among bat species, and some combinations of co-infection were more common than others. Our findings support that co-infections of the three targeted viruses occur in bats in the western Indian Ocean region, although further studies are needed to assess their epidemiological consequences.

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Title: Investigation of astrovirus, coronavirus and paramyxovirus co-infections in bats in the western Indian Ocean
Authors: Axel O. G. Hoarau
Steven M. Goodman
Dana Al Halabi
Beza Ramasindrazana
Erwan Lagadec
Gildas Le Minter
Marie Köster
Andréa Dos Santos
M. Corrie Schoeman
Eduardo S. Gudo
Patrick Mavingui
Camille Lebarbenchon
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Coronavirus
Polymerase Chain Reaction
Published in: Virology Journal / Issue 1/2021
Electronic ISSN: 1743-422X
DOI: https://doi.org/10.1186/s12985-021-01673-2

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