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Journal of the International Society of Sports Nutrition

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Open Access 01-12-2015 | Review

International society of sports nutrition position stand: Beta-Alanine

Authors: Eric T. Trexler, Abbie E. Smith-Ryan, Jeffrey R. Stout, Jay R. Hoffman, Colin D. Wilborn, Craig Sale, Richard B. Kreider, Ralf Jäger, Conrad P. Earnest, Laurent Bannock, Bill Campbell, Douglas Kalman, Tim N. Ziegenfuss, Jose Antonio

Published in: Journal of the International Society of Sports Nutrition | Issue 1/2015

Abstract

Position statement

The International Society of Sports Nutrition (ISSN) provides an objective and critical review of the mechanisms and use of beta-alanine supplementation. Based on the current available literature, the conclusions of the ISSN are as follows: 1) Four weeks of beta-alanine supplementation (4–6 g daily) significantly augments muscle carnosine concentrations, thereby acting as an intracellular pH buffer; 2) Beta-alanine supplementation currently appears to be safe in healthy populations at recommended doses; 3) The only reported side effect is paraesthesia (tingling), but studies indicate this can be attenuated by using divided lower doses (1.6 g) or using a sustained-release formula; 4) Daily supplementation with 4 to 6 g of beta-alanine for at least 2 to 4 weeks has been shown to improve exercise performance, with more pronounced effects in open end-point tasks/time trials lasting 1 to 4 min in duration; 5) Beta-alanine attenuates neuromuscular fatigue, particularly in older subjects, and preliminary evidence indicates that beta-alanine may improve tactical performance; 6) Combining beta-alanine with other single or multi-ingredient supplements may be advantageous when supplementation of beta-alanine is high enough (4–6 g daily) and long enough (minimum 4 weeks); 7) More research is needed to determine the effects of beta-alanine on strength, endurance performance beyond 25 min in duration, and other health-related benefits associated with carnosine.

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Title: International society of sports nutrition position stand: Beta-Alanine
Authors: Eric T. Trexler
Abbie E. Smith-Ryan
Jeffrey R. Stout
Jay R. Hoffman
Colin D. Wilborn
Craig Sale
Richard B. Kreider
Ralf Jäger
Conrad P. Earnest
Laurent Bannock
Bill Campbell
Douglas Kalman
Tim N. Ziegenfuss
Jose Antonio
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of the International Society of Sports Nutrition / Issue 1/2015
Electronic ISSN: 1550-2783
DOI: https://doi.org/10.1186/s12970-015-0090-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

International society of sports nutrition position stand: Beta-Alanine

Abstract

Position statement

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Position statement

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