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Journal of Cardiovascular Magnetic Resonance
Published in: Journal of Cardiovascular Magnetic Resonance 1/2015

Open Access 01-12-2015 | Review

Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide

Authors: Shirjel R. Alam, Colin Stirrat, Jennifer Richards, Saeed Mirsadraee, Scott I. K. Semple, George Tse, Peter Henriksen, David E. Newby

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2015

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Abstract

Cardiovascular Magnetic Resonance (CMR) has become a primary tool for non-invasive assessment of cardiovascular anatomy, pathology and function. Existing contrast agents have been utilised for the identification of infarction, fibrosis, perfusion deficits and for angiography. Novel ultrasmall superparamagnetic particles of iron oxide (USPIO) contrast agents that are taken up by inflammatory cells can detect cellular inflammation non-invasively using CMR, potentially aiding the diagnosis of inflammatory medical conditions, guiding their treatment and giving insight into their pathophysiology. In this review we describe the utilization of USPIO as a novel contrast agent in vascular disease.
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Metadata
Title
Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide
Authors
Shirjel R. Alam
Colin Stirrat
Jennifer Richards
Saeed Mirsadraee
Scott I. K. Semple
George Tse
Peter Henriksen
David E. Newby
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Cardiovascular Magnetic Resonance / Issue 1/2015
Electronic ISSN: 1532-429X
DOI
https://doi.org/10.1186/s12968-015-0183-4

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