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Journal of Translational Medicine
Published in: Journal of Translational Medicine 1/2018

Open Access 01-12-2018 | Review

The role of HIV Tat protein in HIV-related cardiovascular diseases

Authors: Yanan Jiang, Lu Chai, Moyondafoluwa Blessing Fasae, Yunlong Bai

Published in: Journal of Translational Medicine | Issue 1/2018

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Abstract

The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which not only promotes the transcription of HIV, but it is also involved in the pathogenesis of HIV-related complications. This review is aimed at summarizing the current understanding of Tat in HIV-related cardiovascular diseases.
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Metadata
Title
The role of HIV Tat protein in HIV-related cardiovascular diseases
Authors
Yanan Jiang
Lu Chai
Moyondafoluwa Blessing Fasae
Yunlong Bai
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue 1/2018
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/s12967-018-1500-0

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