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Published in: Population Health Metrics 1/2017

Open Access 01-12-2017 | Research

Tuberculosis and HIV are the leading causes of adult death in northwest Ethiopia: evidence from verbal autopsy data of Dabat health and demographic surveillance system, 2007–2013

Authors: Yigzaw Kebede, Gashaw Andargie, Abebaw Gebeyehu, Tadesse Awoke, Mezgebu Yitayal, Solomon Mekonnen, Mamo Wubshet, Temesgen Azmeraw, Yihunie Lakew, Kassahun Alemu

Published in: Population Health Metrics | Issue 1/2017

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Abstract

Background

Reliable data on causes of death form the basis for building evidence on health policy, planning, monitoring, and evaluation. In Ethiopia, the majority of deaths occur at home and civil registration systems are not yet functional. The main objective of verbal autopsy (VA) is to describe the causes of death at the community or population level where civil registration and death certification systems are weak and where most people die at home without having had contact with the health system.

Methods

Causes of death were classified and prepared based on the International Classification of Diseases (ICD-10). The cause of a death was ascertained based on an interview with next of kin or other caregivers using a standardized questionnaire that draws information on signs, symptoms, medical history, and circumstances preceding death. The cause of death, or the sequence of causes that led to death, is assigned based on the data collected by the questionnaire. The complete VA questionnaires were given to two blinded physicians and reviewed independently. A third physician was assigned to review the case when disagreements in diagnosis arose.

Results

Communicable diseases (519 deaths [48.0%]), non-communicable diseases (377 deaths [34.8%]), and external causes (113 deaths [10.4%]) were the main causes of death between 2007 and 2013. Of communicable diseases, tuberculosis (207 deaths [19.7%]), HIV/AIDS (96 deaths [8.9%]) and meningitis (76 deaths [7.0%]) were the most common causes of death.

Conclusion

Tuberculosis, HIV/AIDS, and meningitis were the most common causes of deaths among adults. Death due to non-communicable diseases showed an increasing trend. Increasing community awareness of infections and their interrelationships, tuberculosis case finding, effective local TB programs, successful treatment, and interventions for HIV are supremely important.
Literature
1.
go back to reference Rao C, Lopez AD, Hemed Y. Disease and mortality in sub-Saharan Africa. In: Jamison DT, ed. Causes of death. 2nd ed. Washington (DC): World Bank; 2006. Rao C, Lopez AD, Hemed Y. Disease and mortality in sub-Saharan Africa. In: Jamison DT, ed. Causes of death. 2nd ed. Washington (DC): World Bank; 2006.
2.
go back to reference Lopez AD, Mathers CD. Measuring the global burden of disease and epidemiological transitions: 2002–2030. Ann Trop Med Parasitol. 2006;100(5–6):481–99.CrossRefPubMed Lopez AD, Mathers CD. Measuring the global burden of disease and epidemiological transitions: 2002–2030. Ann Trop Med Parasitol. 2006;100(5–6):481–99.CrossRefPubMed
3.
go back to reference Mathers CD. Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ. 2005;83(3):171–7.PubMedPubMedCentral Mathers CD. Counting the dead and what they died from: an assessment of the global status of cause of death data. Bull World Health Organ. 2005;83(3):171–7.PubMedPubMedCentral
4.
go back to reference Thatte N, Kalter HD, Baqui AH, Williams EM, Darmstadt GL. Ascertaining causes of neonatal deaths using verbal autopsy: current methods and challenges. J Perinatol 2009;29:187–94. Thatte N, Kalter HD, Baqui AH, Williams EM, Darmstadt GL. Ascertaining causes of neonatal deaths using verbal autopsy: current methods and challenges. J Perinatol 2009;29:187–94.
5.
go back to reference Gore FMBP, Patton GC, Ferguson J, Joseph V, et al. Global burden of disease in young people aged 10-24 years: a systematic analysis. Lancet. 2011;377:2093–102.CrossRefPubMed Gore FMBP, Patton GC, Ferguson J, Joseph V, et al. Global burden of disease in young people aged 10-24 years: a systematic analysis. Lancet. 2011;377:2093–102.CrossRefPubMed
6.
go back to reference van’t Hoog AWJ, Sewe M, Mboya P, Odeny L. Risk factors for excess mortality and death in adults with tuberculosis in western Kenya. Int J TB Lung Dis. 2012;8:231–321. van’t Hoog AWJ, Sewe M, Mboya P, Odeny L. Risk factors for excess mortality and death in adults with tuberculosis in western Kenya. Int J TB Lung Dis. 2012;8:231–321.
7.
go back to reference Melaku YA, Sahle BW, Tesfay FH, Bezabih AM, Aregay A, Abera SF. Causes of death among adults in northern Ethiopia: evidence from verbal autopsy data in health and demographic surveillance system. PLoS One. 2014;9(9). doi:10.1371/journal.pone.0106781. Melaku YA, Sahle BW, Tesfay FH, Bezabih AM, Aregay A, Abera SF. Causes of death among adults in northern Ethiopia: evidence from verbal autopsy data in health and demographic surveillance system. PLoS One. 2014;9(9). doi:10.​1371/​journal.​pone.​0106781.
8.
go back to reference EPHA. Ethiopian Universities Health and Demographic Surveillance System Network Data Sharing and Release Policy. 2013. EPHA. Ethiopian Universities Health and Demographic Surveillance System Network Data Sharing and Release Policy. 2013.
9.
go back to reference Patton GCCC, Sawyer SM, Viner RM, Haller DM, et al. Global patterns of mortality in young people: a systematic analysis of population health data. Lancet. 2009;374:881–92.CrossRefPubMed Patton GCCC, Sawyer SM, Viner RM, Haller DM, et al. Global patterns of mortality in young people: a systematic analysis of population health data. Lancet. 2009;374:881–92.CrossRefPubMed
10.
go back to reference WHO, International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) Version for 2010. 2010. WHO, International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) Version for 2010. 2010.
11.
go back to reference WHO. WHO, Verbal autopsy standards: The 2007 WHO ascertaining and attributing causes of death. Geneva: World Health Organization; 2007. p. 112. ISBN 978 92 4 154721. WHO. WHO, Verbal autopsy standards: The 2007 WHO ascertaining and attributing causes of death. Geneva: World Health Organization; 2007. p. 112. ISBN 978 92 4 154721.
12.
go back to reference Fottrell E, Kahn K, Ng N, Sartorius B, Huong DL, Minh HV, et al. Mortality measurement in transition: proof of principle for standardised multi-country comparisons. Trop Med Int Health. 2010;15(10):1256–65.CrossRefPubMedPubMedCentral Fottrell E, Kahn K, Ng N, Sartorius B, Huong DL, Minh HV, et al. Mortality measurement in transition: proof of principle for standardised multi-country comparisons. Trop Med Int Health. 2010;15(10):1256–65.CrossRefPubMedPubMedCentral
14.
go back to reference WHO. International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) Version for 2010. 2010. WHO. International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) Version for 2010. 2010.
17.
go back to reference Alexander SA, Sengupta P, Benjamin AI. Causes of Adult deaths by verbal autopsy in an urban slum of Ludhiana. Indian J Clin Prac. 2013;24(7):623–5. Alexander SA, Sengupta P, Benjamin AI. Causes of Adult deaths by verbal autopsy in an urban slum of Ludhiana. Indian J Clin Prac. 2013;24(7):623–5.
18.
go back to reference Kyobutungi CZA, Ezeh A, Ye Y. The burden of disease profile of residents of Nairobi's slums: results from a demographic surveillance system. Popul Health Metr. 2008:6(1). Kyobutungi CZA, Ezeh A, Ye Y. The burden of disease profile of residents of Nairobi's slums: results from a demographic surveillance system. Popul Health Metr. 2008:6(1).
19.
go back to reference Viner RMCC, Mathers C, Bloem P, Costello A, et al. 50-year mortality trends in children and young people: a study of 50 low-income, middle-income, and high-income countries. Lancet. 2011;377:1162–74.CrossRefPubMed Viner RMCC, Mathers C, Bloem P, Costello A, et al. 50-year mortality trends in children and young people: a study of 50 low-income, middle-income, and high-income countries. Lancet. 2011;377:1162–74.CrossRefPubMed
20.
go back to reference Conti SFG, Prati S. AIDS as a leading cause of death among young adults in Italy. Eur J Epidemiol. 1994;10(6):669–73.CrossRefPubMed Conti SFG, Prati S. AIDS as a leading cause of death among young adults in Italy. Eur J Epidemiol. 1994;10(6):669–73.CrossRefPubMed
21.
go back to reference April KKR. AIDS--a leading cause of death among young people in Switzerland. Schweiz Med Wochenschr. 1994;124(47):2119–22.PubMed April KKR. AIDS--a leading cause of death among young people in Switzerland. Schweiz Med Wochenschr. 1994;124(47):2119–22.PubMed
22.
go back to reference Herbst AJ, Mafojane T, Newell M-L. Verbal autopsy-based cause-specific mortality trends in rural KwaZulu-Natal, South Africa, 2000-2009. Popul Health Metr. 2011;9:47.CrossRefPubMedPubMedCentral Herbst AJ, Mafojane T, Newell M-L. Verbal autopsy-based cause-specific mortality trends in rural KwaZulu-Natal, South Africa, 2000-2009. Popul Health Metr. 2011;9:47.CrossRefPubMedPubMedCentral
23.
go back to reference Weisfelt M. Beek Dvd, Spanjaard L, Reitsma JB, Gans Jd. Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol. 2006;5:123–9.CrossRefPubMed Weisfelt M. Beek Dvd, Spanjaard L, Reitsma JB, Gans Jd. Clinical features, complications, and outcome in adults with pneumococcal meningitis: a prospective case series. Lancet Neurol. 2006;5:123–9.CrossRefPubMed
24.
go back to reference Blessing Mberu MW. Samuel Oti, and Catherine Kyobutungi. Trends in causes of Adult deaths among the urban poor: evidence from Nairobi urban health and demographic surveillance system, 2003–2012. Bull N Y Acad Med. 2015. Blessing Mberu MW. Samuel Oti, and Catherine Kyobutungi. Trends in causes of Adult deaths among the urban poor: evidence from Nairobi urban health and demographic surveillance system, 2003–2012. Bull N Y Acad Med. 2015.
25.
go back to reference LA PH, Portos JL. Cardiovascular diseases in aged subjects. Results of a morbidity survey in an old age home. Sem Hop. 1965:141(51). LA PH, Portos JL. Cardiovascular diseases in aged subjects. Results of a morbidity survey in an old age home. Sem Hop. 1965:141(51).
26.
go back to reference Stahelin HBE-FD, Meier D. Cardiovascular diseases, cognitive abilities and quality of life in old age. Praxis. 1995;84(44):1256–8.PubMed Stahelin HBE-FD, Meier D. Cardiovascular diseases, cognitive abilities and quality of life in old age. Praxis. 1995;84(44):1256–8.PubMed
27.
go back to reference Mendis S DS, Norrving B. Organizational update: the world health organization global status report on noncommunicable diseases 2014; one more landmark step in the combat against stroke and vascular disease. Stroke. 2015;46(5). Mendis S DS, Norrving B. Organizational update: the world health organization global status report on noncommunicable diseases 2014; one more landmark step in the combat against stroke and vascular disease. Stroke. 2015;46(5).
28.
go back to reference Bygbjerg IC. Double burden of noncommunicable and infectious diseases in developing countries. Science. 2012;337(6101):1499–501.CrossRefPubMed Bygbjerg IC. Double burden of noncommunicable and infectious diseases in developing countries. Science. 2012;337(6101):1499–501.CrossRefPubMed
30.
go back to reference Boutayeb A. The double burden of communicable and non-communicable diseases in developing countries. Trans R Soc Trop Med Hyg. 2006;100(3):191–9.CrossRefPubMed Boutayeb A. The double burden of communicable and non-communicable diseases in developing countries. Trans R Soc Trop Med Hyg. 2006;100(3):191–9.CrossRefPubMed
31.
go back to reference Narh-Bana SACT, Mwanyangala MA, Nathan R. Adult deaths and the future: a cause-specific analysis of adult deaths from a longitudinal study in rural Tanzania 2003-2007. Trop Med Int Health. 2012;17(11):1396–404.CrossRefPubMed Narh-Bana SACT, Mwanyangala MA, Nathan R. Adult deaths and the future: a cause-specific analysis of adult deaths from a longitudinal study in rural Tanzania 2003-2007. Trop Med Int Health. 2012;17(11):1396–404.CrossRefPubMed
32.
go back to reference Palanivel CYK, Gupta V, Rai SK, Misra P, Krishnan A. Causes of death in rural adult population of North India (2002-2007), using verbal autopsy tool. Indian J Public Health. 2013;57(2):78–83.CrossRefPubMed Palanivel CYK, Gupta V, Rai SK, Misra P, Krishnan A. Causes of death in rural adult population of North India (2002-2007), using verbal autopsy tool. Indian J Public Health. 2013;57(2):78–83.CrossRefPubMed
33.
go back to reference Fujihara JKT, Agusa T, Yasuda T, Iida R, Fujii Y, Takeshita H. Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method. Toxicol Appl Pharmacol. 2007;225(3):251–4.CrossRefPubMed Fujihara JKT, Agusa T, Yasuda T, Iida R, Fujii Y, Takeshita H. Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method. Toxicol Appl Pharmacol. 2007;225(3):251–4.CrossRefPubMed
34.
go back to reference Sang WKIT, Yamamoto H, Saidi SM, Yoh M, Waiyaki PG, Ezaki T, et al. Prevalence of diarrhoeagenic Escherichia coli in Kenyan children. J Diarrhoeal Dis Res. 1996;14(3):216–7. Sang WKIT, Yamamoto H, Saidi SM, Yoh M, Waiyaki PG, Ezaki T, et al. Prevalence of diarrhoeagenic Escherichia coli in Kenyan children. J Diarrhoeal Dis Res. 1996;14(3):216–7.
35.
go back to reference Weldearegawi B, Ashebir Y, Gebeye E, Gebregziabiher T, Yohannes M, et al. Emerging chronic non-communicable diseases in rural communities of Northern Ethiopia: evidence using population-based verbal autopsy method in Kilite Awlaelo surveillance site. Health Policy Plan. 2013;28:891–8.CrossRefPubMed Weldearegawi B, Ashebir Y, Gebeye E, Gebregziabiher T, Yohannes M, et al. Emerging chronic non-communicable diseases in rural communities of Northern Ethiopia: evidence using population-based verbal autopsy method in Kilite Awlaelo surveillance site. Health Policy Plan. 2013;28:891–8.CrossRefPubMed
36.
go back to reference Misganaw A, Araya T, Ayele K. Patterns of mortality in public and private hospitals of Addis Ababa, Ethiopia. 2012;12:1007. Epub 2012/11/22. BMC Public Health. 2012;1007 Epub 2012/11/22 Misganaw A, Araya T, Ayele K. Patterns of mortality in public and private hospitals of Addis Ababa, Ethiopia. 2012;12:1007. Epub 2012/11/22. BMC Public Health. 2012;1007 Epub 2012/11/22
37.
go back to reference Franca E, Campos D, Guimaraes MD, Souza MF. Use of verbal autopsy in a national health information system: effects of the investigation of ill-defined causes of death on proportional mortality due to injury in small municipalities in Brazil. Popul Health Metr. 2011;9:39.CrossRefPubMedPubMedCentral Franca E, Campos D, Guimaraes MD, Souza MF. Use of verbal autopsy in a national health information system: effects of the investigation of ill-defined causes of death on proportional mortality due to injury in small municipalities in Brazil. Popul Health Metr. 2011;9:39.CrossRefPubMedPubMedCentral
38.
go back to reference Baqui AH, Black RE, Arifeen SE, Hill K, Mitra SN. Al Sabir a. Causes of childhood deaths in Bangladesh: results of a nationwide verbal autopsy study. Bull World Health Organ. 1998;76(2):161–71.PubMedPubMedCentral Baqui AH, Black RE, Arifeen SE, Hill K, Mitra SN. Al Sabir a. Causes of childhood deaths in Bangladesh: results of a nationwide verbal autopsy study. Bull World Health Organ. 1998;76(2):161–71.PubMedPubMedCentral
39.
go back to reference Dharmaratne SD, Jayasuriya RJ, Perera BY, Gunesekera EM, Sathasivayyar A. Opportunities and challenges for verbal autopsy in the national death registration system in Sri Lanka: past and future. Popul Health Metr. 2011;9(21). doi:10.1186/478-7954-9-21. Dharmaratne SD, Jayasuriya RJ, Perera BY, Gunesekera EM, Sathasivayyar A. Opportunities and challenges for verbal autopsy in the national death registration system in Sri Lanka: past and future. Popul Health Metr. 2011;9(21). doi:10.​1186/​478-7954-9-21.
40.
go back to reference Mbofana F. Lewis R WL, Mazive E, Cummings S, Mswia R. Using verbal autopsy in a post-census mortality survey to capture causes of death in Mozambique, 2006–2007. Bali: Global Congress on Verbal Autopsy. State of Science; 2011. Mbofana F. Lewis R WL, Mazive E, Cummings S, Mswia R. Using verbal autopsy in a post-census mortality survey to capture causes of death in Mozambique, 2006–2007. Bali: Global Congress on Verbal Autopsy. State of Science; 2011.
41.
go back to reference Misganaw A, Mariam DH, Araya T, Aneneh A. Validity of verbal autopsy method to determine causes of death among adults in the urban setting of Ethiopia. BMC Med Res Methodol. 2012;12(1):1.CrossRef Misganaw A, Mariam DH, Araya T, Aneneh A. Validity of verbal autopsy method to determine causes of death among adults in the urban setting of Ethiopia. BMC Med Res Methodol. 2012;12(1):1.CrossRef
Metadata
Title
Tuberculosis and HIV are the leading causes of adult death in northwest Ethiopia: evidence from verbal autopsy data of Dabat health and demographic surveillance system, 2007–2013
Authors
Yigzaw Kebede
Gashaw Andargie
Abebaw Gebeyehu
Tadesse Awoke
Mezgebu Yitayal
Solomon Mekonnen
Mamo Wubshet
Temesgen Azmeraw
Yihunie Lakew
Kassahun Alemu
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Population Health Metrics / Issue 1/2017
Electronic ISSN: 1478-7954
DOI
https://doi.org/10.1186/s12963-017-0139-z

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