Skip to main content
Top
Published in: Cost Effectiveness and Resource Allocation 1/2018

Open Access 01-12-2018 | Research

Brief interventions to address substance use among patients presenting to emergency departments in resource poor settings: a cost-effectiveness analysis

Authors: Rebecca Dwommoh, Katherine Sorsdahl, Bronwyn Myers, Kwaku Poku Asante, Tracey Naledi, Dan J. Stein, Susan Cleary

Published in: Cost Effectiveness and Resource Allocation | Issue 1/2018

Login to get access

Abstract

Background

There are limited data describing the cost-effectiveness of brief interventions for substance use in resource-poor settings. Using a patient and provider perspective, this study investigates the cost-effectiveness of a brief motivational interviewing (MI) intervention versus a combined intervention of MI and problem solving therapy (MI-PST) for reducing substance use among patients presenting to emergency departments, in comparison to a control group.

Methods

Effectiveness data were extracted from Project STRIVE (Substance use and Trauma InterVention) conducted in South Africa. Patients were randomised to either receive 1 session of MI (n = 113) or MI in addition to four sessions of PST (n = 109) or no intervention [control (n = 110)]. Costs included the direct health care costs associated with the interventions. Patient costs included out of pocket payments incurred accessing the MI-PST intervention. Outcome measures were patients’ scores on the Alcohol, Smoking and Substance Use Involvement Screening Test (ASSIST) and the Centre for Epidemiological Studies Depression Scale (CES-D).

Results

Cost per patient was low in all three groups; US$16, US$33 and US$11, and for MI, MI-PST and control respectively. Outcomes were 0.92 (MI), 1.06 (MI-PST) and 0.88 (control) for ASSIST scores; and 0.74 (MI), 1.27 (MI-PST) and 0.53 (control) for CES-D scores. In comparison to the control group, the MI intervention costs an additional US$119 per unit reduction in ASSIST score, (US$20 for CES-D); MI-PST in comparison to MI costs US$131 or US$33 per unit reduction in ASSIST or CES-D scores respectively. The sensitivity analyses showed that increasing the number of patients who screened positive and thus received the intervention could improve the effectiveness and cost-effectiveness of the interventions.

Conclusion

MI or MI-PST interventions delivered by lay counsellors have the potential to be cost-effective strategies for the reduction of substance use disorder and depressive symptoms among patients presenting at emergency departments in resource poor settings. Given the high economic, social and health care cost of substance use disorders in South Africa, these results suggest that these interventions should be carefully considered for future implementation.
Trial registration This study is part of a trial registered with the Pan African Clinical Trial Registry (PACTR201308000591418)
Literature
1.
go back to reference World Health Organization. Atlas on substance Use (2010): Resources for the prevention and treatment of substance use disorders. World Heal Organ. 2010:156. World Health Organization. Atlas on substance Use (2010): Resources for the prevention and treatment of substance use disorders. World Heal Organ. 2010:156.
3.
go back to reference Stein DJ, Seedat S, Herman A, Moomal H, Heeringa SG, Kessler RC, et al. Lifetime prevalence of psychiatric disorders in South Africa. Br J Psychiatry. 2008;192:112–7.CrossRefPubMedPubMedCentral Stein DJ, Seedat S, Herman A, Moomal H, Heeringa SG, Kessler RC, et al. Lifetime prevalence of psychiatric disorders in South Africa. Br J Psychiatry. 2008;192:112–7.CrossRefPubMedPubMedCentral
4.
go back to reference Meade CS, Towe SL, Watt MH, Lion RR, Myers B, Skinner D, et al. Addiction and treatment experiences among active methamphetamine users recruited from a township community in Cape Town, South Africa: a mixed-methods study. Drug Alcohol Depend. 2015;152:79–86.CrossRefPubMedPubMedCentral Meade CS, Towe SL, Watt MH, Lion RR, Myers B, Skinner D, et al. Addiction and treatment experiences among active methamphetamine users recruited from a township community in Cape Town, South Africa: a mixed-methods study. Drug Alcohol Depend. 2015;152:79–86.CrossRefPubMedPubMedCentral
5.
go back to reference Myers B, Kline TL, Doherty IA, Carney T, Wechsberg WM. Perceived need for substance use treatment among young women from disadvantaged communities in Cape Town, South Africa. BMC Psychiatry. 2014;14:100.CrossRefPubMedPubMedCentral Myers B, Kline TL, Doherty IA, Carney T, Wechsberg WM. Perceived need for substance use treatment among young women from disadvantaged communities in Cape Town, South Africa. BMC Psychiatry. 2014;14:100.CrossRefPubMedPubMedCentral
6.
go back to reference Perngparn U, Assanangkornchai S, Pilley C, Aramrattana A. Drug and alcohol services in middle-income countries. Curr Opin Psychiatry. 2008;21:229–33.CrossRefPubMed Perngparn U, Assanangkornchai S, Pilley C, Aramrattana A. Drug and alcohol services in middle-income countries. Curr Opin Psychiatry. 2008;21:229–33.CrossRefPubMed
7.
go back to reference Myers B, Sorsdahl K. Addressing substance use within primary health care settings in South Africa: opportunities and challenges. Addicta Turk J Addict. 2014;1:80–94. Myers B, Sorsdahl K. Addressing substance use within primary health care settings in South Africa: opportunities and challenges. Addicta Turk J Addict. 2014;1:80–94.
8.
go back to reference Schermer CR. Feasibility of alcohol screening and brief intervention. J Trauma Acute Care Surg. 2005;59:S119–23.CrossRef Schermer CR. Feasibility of alcohol screening and brief intervention. J Trauma Acute Care Surg. 2005;59:S119–23.CrossRef
9.
go back to reference Gentilello LM, Ebel BE, Wickizer TM, Salkever DS, Rivara FP. Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysis. Ann Surg. 2005;241:541.CrossRefPubMedPubMedCentral Gentilello LM, Ebel BE, Wickizer TM, Salkever DS, Rivara FP. Alcohol interventions for trauma patients treated in emergency departments and hospitals: a cost benefit analysis. Ann Surg. 2005;241:541.CrossRefPubMedPubMedCentral
10.
go back to reference Nilsen P, Baird J, Mello MJ, Nirenberg T, Woolard R, Bendtsen P, et al. A systematic review of emergency care brief alcohol interventions for injury patients. J Subst Abuse Treat. 2008;35:184–201.CrossRefPubMed Nilsen P, Baird J, Mello MJ, Nirenberg T, Woolard R, Bendtsen P, et al. A systematic review of emergency care brief alcohol interventions for injury patients. J Subst Abuse Treat. 2008;35:184–201.CrossRefPubMed
11.
go back to reference Herman AA, Stein DJ, Seedat S, Heeringa SG, Moomal H, Williams DR. The South African Stress and Health (SASH) study: 12-month and lifetime prevalence of common mental disorders. South Afr Med J (SAMJ). 2009;99:339–44. Herman AA, Stein DJ, Seedat S, Heeringa SG, Moomal H, Williams DR. The South African Stress and Health (SASH) study: 12-month and lifetime prevalence of common mental disorders. South Afr Med J (SAMJ). 2009;99:339–44.
12.
go back to reference Sorsdahl K, Stein DJ, Corrigall J, Cuijpers P, Smits N, Naledi T, et al. The efficacy of a blended motivational interviewing and problem solving therapy intervention to reduce substance use among patients presenting for emergency services in South Africa: a randomized controlled trial. Subst Abuse Treat Prev Policy. 2015;10:46.CrossRefPubMedPubMedCentral Sorsdahl K, Stein DJ, Corrigall J, Cuijpers P, Smits N, Naledi T, et al. The efficacy of a blended motivational interviewing and problem solving therapy intervention to reduce substance use among patients presenting for emergency services in South Africa: a randomized controlled trial. Subst Abuse Treat Prev Policy. 2015;10:46.CrossRefPubMedPubMedCentral
13.
go back to reference Drummond MF, Sculpher MJ, Torrance GW, O’Brien BJ, Stoddart GL. Methods for the economic evaluation of health care programmes. Oxford: Oxford University Press; 2005. Drummond MF, Sculpher MJ, Torrance GW, O’Brien BJ, Stoddart GL. Methods for the economic evaluation of health care programmes. Oxford: Oxford University Press; 2005.
16.
go back to reference Western Cape Crime Overview 2014/15 Analysis of Crime Statistics as released by the South African Police Service on 29th of September 2015. 2015. Western Cape Crime Overview 2014/15 Analysis of Crime Statistics as released by the South African Police Service on 29th of September 2015. 2015.
17.
go back to reference Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385–401.CrossRef Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385–401.CrossRef
18.
go back to reference Myers B, Stein DJ, Mtukushe B, Sorsdahl K. Feasibility and acceptability of screening and brief interventions to address alcohol and other drug use among patients presenting for emergency services in Cape Town, South Africa. Adv Prev Med. 2012;2012:569153.CrossRefPubMedPubMedCentral Myers B, Stein DJ, Mtukushe B, Sorsdahl K. Feasibility and acceptability of screening and brief interventions to address alcohol and other drug use among patients presenting for emergency services in Cape Town, South Africa. Adv Prev Med. 2012;2012:569153.CrossRefPubMedPubMedCentral
19.
go back to reference Organization WH. The alcohol, smoking and substance involvement screening test (ASSIST): manual for use in primary care. Geneva: World Heal Organ; 2010. Organization WH. The alcohol, smoking and substance involvement screening test (ASSIST): manual for use in primary care. Geneva: World Heal Organ; 2010.
20.
go back to reference D’Zurilla TJ, Nezu AM. Problem-solving therapy. Handb Cogn Ther. 2010;3:197–225. D’Zurilla TJ, Nezu AM. Problem-solving therapy. Handb Cogn Ther. 2010;3:197–225.
21.
go back to reference D’zurilla TJ, Goldfried MR. Problem solving and behavior modification. J Abnorm Psychol. 1971;78:107.CrossRefPubMed D’zurilla TJ, Goldfried MR. Problem solving and behavior modification. J Abnorm Psychol. 1971;78:107.CrossRefPubMed
23.
go back to reference Karnon J, Brown J. Selecting a decision model for economic evaluation: a case study and review. Health Care Manag Sci. 1998;1:133–40.CrossRefPubMed Karnon J, Brown J. Selecting a decision model for economic evaluation: a case study and review. Health Care Manag Sci. 1998;1:133–40.CrossRefPubMed
24.
go back to reference Briggs A. Handling uncertainty in the results of economic evaluation. OHE Brief. 1995;32:1–12. Briggs A. Handling uncertainty in the results of economic evaluation. OHE Brief. 1995;32:1–12.
26.
go back to reference Buttorff C, Hock RS, Weiss HA, Naik S, Araya R, Kirkwood BR, et al. Economic evaluation of a task-shifting intervention for common mental disorders in India. Bull World Health Organ. 2012;90:813–21.CrossRefPubMedPubMedCentral Buttorff C, Hock RS, Weiss HA, Naik S, Araya R, Kirkwood BR, et al. Economic evaluation of a task-shifting intervention for common mental disorders in India. Bull World Health Organ. 2012;90:813–21.CrossRefPubMedPubMedCentral
27.
go back to reference Kakuma R, Minas H, van Ginneken N, Dal Poz MR, Desiraju K, Morris JE, et al. Human resources for mental health care: current situation and strategies for action. Lancet. 2011;378:1654–63.CrossRefPubMed Kakuma R, Minas H, van Ginneken N, Dal Poz MR, Desiraju K, Morris JE, et al. Human resources for mental health care: current situation and strategies for action. Lancet. 2011;378:1654–63.CrossRefPubMed
28.
go back to reference Petersen I, Lund C, Bhana A, Flisher AJ. A task shifting approach to primary mental health care for adults in South Africa: human resource requirements and costs for rural settings. Health Policy Plan. 2012;27:42–51.CrossRefPubMed Petersen I, Lund C, Bhana A, Flisher AJ. A task shifting approach to primary mental health care for adults in South Africa: human resource requirements and costs for rural settings. Health Policy Plan. 2012;27:42–51.CrossRefPubMed
29.
go back to reference Barrett B, Byford S, Crawford MJ, Patton R, Drummond C, Henry JA, et al. Cost-effectiveness of screening and referral to an alcohol health worker in alcohol misusing patients attending an accident and emergency department: a decision-making approach. Drug Alcohol Depend. 2006;81:47–54.CrossRefPubMed Barrett B, Byford S, Crawford MJ, Patton R, Drummond C, Henry JA, et al. Cost-effectiveness of screening and referral to an alcohol health worker in alcohol misusing patients attending an accident and emergency department: a decision-making approach. Drug Alcohol Depend. 2006;81:47–54.CrossRefPubMed
30.
go back to reference Kunz FM Jr, French MT, Bazargan-Hejazi S. Cost-effectiveness analysis of a brief intervention delivered to problem drinkers presenting at an inner-city hospital emergency department. J Stud Alcohol. 2004;65:363–70.CrossRefPubMed Kunz FM Jr, French MT, Bazargan-Hejazi S. Cost-effectiveness analysis of a brief intervention delivered to problem drinkers presenting at an inner-city hospital emergency department. J Stud Alcohol. 2004;65:363–70.CrossRefPubMed
31.
go back to reference Neighbors CJ, Barnett NP, Rohsenow DJ, Colby SM, Monti PM. Cost-effectiveness of a motivational lntervention for alcohol-involved youth in a hospital emergency department. J Stud Alcohol Drugs. 2010;71:384–94.CrossRefPubMedPubMedCentral Neighbors CJ, Barnett NP, Rohsenow DJ, Colby SM, Monti PM. Cost-effectiveness of a motivational lntervention for alcohol-involved youth in a hospital emergency department. J Stud Alcohol Drugs. 2010;71:384–94.CrossRefPubMedPubMedCentral
32.
go back to reference Birch S, Gafni A. Information created to evade reality (ICER). Pharmacoeconomics. 2006;24:1121–31.CrossRefPubMed Birch S, Gafni A. Information created to evade reality (ICER). Pharmacoeconomics. 2006;24:1121–31.CrossRefPubMed
33.
go back to reference Cowell AJ, Brown JM, Mills MJ, Bender RH, Wedehase BJ. Cost-effectiveness analysis of motivational interviewing with feedback to reduce drinking among a sample of college students. J Stud Alcohol Drugs. 2012;73:226–37.CrossRefPubMedPubMedCentral Cowell AJ, Brown JM, Mills MJ, Bender RH, Wedehase BJ. Cost-effectiveness analysis of motivational interviewing with feedback to reduce drinking among a sample of college students. J Stud Alcohol Drugs. 2012;73:226–37.CrossRefPubMedPubMedCentral
34.
go back to reference Cowell AJ, Bray JW, Mills MJ, Hinde JM. Conducting economic evaluations of screening and brief intervention for hazardous drinking: methods and evidence to date for informing policy. Drug Alcohol Rev. 2010;29:623–30.CrossRefPubMedPubMedCentral Cowell AJ, Bray JW, Mills MJ, Hinde JM. Conducting economic evaluations of screening and brief intervention for hazardous drinking: methods and evidence to date for informing policy. Drug Alcohol Rev. 2010;29:623–30.CrossRefPubMedPubMedCentral
35.
go back to reference Weinstein MC, Torrance G, McGuire A. QALYs: the basics. Value Heal. 2009;12:S5–9.CrossRef Weinstein MC, Torrance G, McGuire A. QALYs: the basics. Value Heal. 2009;12:S5–9.CrossRef
36.
go back to reference Matzopoulos RG, Truen S, Bowman B, Corrigall J. The cost of harmful alcohol use in South Africa. South Afr Med J (SAMJ). 2014;104:127–32.CrossRef Matzopoulos RG, Truen S, Bowman B, Corrigall J. The cost of harmful alcohol use in South Africa. South Afr Med J (SAMJ). 2014;104:127–32.CrossRef
Metadata
Title
Brief interventions to address substance use among patients presenting to emergency departments in resource poor settings: a cost-effectiveness analysis
Authors
Rebecca Dwommoh
Katherine Sorsdahl
Bronwyn Myers
Kwaku Poku Asante
Tracey Naledi
Dan J. Stein
Susan Cleary
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Cost Effectiveness and Resource Allocation / Issue 1/2018
Electronic ISSN: 1478-7547
DOI
https://doi.org/10.1186/s12962-018-0109-8

Other articles of this Issue 1/2018

Cost Effectiveness and Resource Allocation 1/2018 Go to the issue