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Reproductive Biology and Endocrinology
Published in: Reproductive Biology and Endocrinology 1/2017

Open Access 01-12-2017 | Commentary

Comment on "Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation"

Authors: Ospan A. Mynbaev, Antonio Malvasi, Sergei S. Simakov, Andrea Tinelli

Published in: Reproductive Biology and Endocrinology | Issue 1/2017

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Abstract

Background

The cause of contamination and dissemination of leiomyoma tissue particles and cells in the peritoneal cavity during myomectomy is a challenging issue for both clinicians and researchers. Therefore, the article by Huang et al. recently published in your journal is the subject of this letter.

Main body

We comment on the role of laparoscopic condition in xenograft implantation and also highlighted the shortcomings of this study. The surgical technique of intramural fibroid enucleation, cell spillage during morcellation and postsurgical hormonal impact on the development of parasitic myomas become evident, while the contribution of CO2 insufflation, the fibroid’s nature, mutations and pseudocapsule impacts on angiogenesis are not clear. In addition, an exploration of the exact origin of implanted fragments harvested from the fibroid tissue and their nature might play a significant role in the implantation and the angiogenesis induction ability of xenografts.

Conclusion

Taking into account the current literature in the scope of this study, we suggest that the factors involved in development of parasitic myomas can be classified as confirmed and doubtful contributions.
Literature
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Wright JD, Chen L, Burke WM, Hou JY, Tergas AI, Ananth CV, Hershman DL. Trends in use and outcomes of women undergoing hysterectomy with electric power Morcellation. JAMA. 2016 Aug 23–30;316(8):877–878.
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Metadata
Title
Comment on "Oestrogen-induced angiogenesis and implantation contribute to the development of parasitic myomas after laparoscopic morcellation"
Authors
Ospan A. Mynbaev
Antonio Malvasi
Sergei S. Simakov
Andrea Tinelli
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Reproductive Biology and Endocrinology / Issue 1/2017
Electronic ISSN: 1477-7827
DOI
https://doi.org/10.1186/s12958-017-0268-z

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