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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2017

Open Access 01-12-2017 | Case Report

Giant gastrointestinal stromal tumor with predominantly cystic changes: a case report and literature review

Authors: Liying Wang, Libin Liu, Zhaohui Liu, Yueli Tian, Zhe Lin

Published in: World Journal of Surgical Oncology | Issue 1/2017

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Abstract

Background

Gastrointestinal stromal tumors (GISTs) rarely present with predominantly cystic changes. Here, we report a case of giant GIST of the stomach with predominantly cystic changes in a 74-year-old female patient.

Case presentation

The tumor was 10 cm × 15 cm in size and positive for CD117, H-caldesmon, and DOG-1. Complete surgical resection was performed without regional lymphadenectomy. The patient recovered uneventfully and no recurrence occurred.

Conclusions

The case illustrates that GIST with cystic changes should be considered in the diagnoses of hepatic and pancreatic lesions. Furthermore, immunohistochemistry with CD117, DOG1, and other molecular markers is critical for diagnosis of GIST of the stomach and facilitates optimization of treatments for GIST.
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Metadata
Title
Giant gastrointestinal stromal tumor with predominantly cystic changes: a case report and literature review
Authors
Liying Wang
Libin Liu
Zhaohui Liu
Yueli Tian
Zhe Lin
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2017
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-017-1285-2

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